In fiecare colț al României, tradițiile noastre bogate sunt păstrate cu grijă, iar aromele caracteristice ale produselor locale ne amintesc de moștenirea culturală pe care o purtăm cu mândrie. De la brânzeturile artizanale la gemurile din fructe de pădure, fiecare produs are o poveste de spus și o experiență unică de oferit. Într-o lume care se schimbă rapid, este esențial să ne reconectăm cu aceste tradiții și să descoperim gusturile care ne definesc.

Pe blogul nostru romanesc, ne propunem să aducem în prim-plan aceste comori gastronomice prin recenzii detaliate și păreri autentice. Astfel, cititorii pot explora o varietate de produse românești, găsind inspirația necesară pentru a încorpora aromele tradiționale în viața de zi cu zi. Fie că ești un pasionat de gastronomie sau doar curios să încerci ceva nou, te invităm să ne însoțiți în această călătorie delicioasă a descoperirii aromelor tradițiilor noastre.

Produse Tradiționale Romanesti

Romania este cunoscută pentru diversitatea sa culinară, iar produsele tradiționale românești sunt un adevărat deliciu pentru simțuri. De la brânza de burduf, cu aroma sa intensă, până la zacusca de vinete, fiecare produs are o poveste și un gust unic. Aceste delicii reflectă bogăția ingredientelor locale și meșteșugul străvechi al alimentației românești, aducând împreună tradiții care au fost transmise din generație în generație.

Un alt produs emblematic este mămăliga, care a fost parte integrantă a mesei românești timp de secole. Preparată din mălai, mămăliga poate fi servită ca garnitură sau ca fel principal, alături de brânză, smântână sau carne. Este un simbol al ospitalității și al bucuriei de a împărtăși o masă cu cei dragi. Puterea mămăligii stă în simplitatea sa, dar și în versatilele combinații ce pot fi realizate.

Nu putem uita de vinurile românești, care sunt la fel de variate ca și peisajele țării. De la vinurile de la Cotnari sau Murfatlar, fiecare are caracteristici specifice, influențate de terroir-ul local. Degustarea vinului românesc este o călătorie în sine, ce ne îmbie să explorăm paleta bogată de arome și să ne bucurăm de tradițiile vinificației, transformând fiecare pahar într-o experiență memorabilă.

Recenzii și Păreri

Romania este cunoscută pentru bogăția sa în tradiții și gusturi autentice. Pe blogurile românești, părerile utilizatorilor despre diverse produse pot oferi revelații valoroase. De la brânzeturi făcute în casă la dulcețuri aromate, recenziile ascultă vocea iubitorilor de gastronomie care împărtășesc cât de mult le-a plăcut un produs sau cum s-a integrat acesta în cultura lor culinară.

Fie că este vorba despre un blog de produse care analizează fiecare aspect al ingredientelor, sau despre recenzii detaliate care discută despre modul în care un preparat tradițional mai poate fi reinventat, aceste feedback-uri sunt esențiale. Participanții la festuri de bloguri, cum ar fi Blogfest, au ocazia să împărtășească experiențele lor, creând o comunitate vibrantă în jurul pasiunii pentru produsele românești.

Nu doar că aceste recenzii informează, dar ele contribuie și la dezvoltarea unei culturi consumatoare mai conștiente. Citind păreri pe bloguri de specialitate, utilizatorii pot descoperi produse noi care să le încânte simțurile, promovând astfel nu doar produsele locale, ci și un stil de viață sănătos și sustenabil.

Importanța Blogurilor în Cultură

Blogurile joacă un rol esențial în promovarea și conservarea tradițiilor culturale. Ele oferă un spațiu unde pasionații de https://blogfest.ro/ împărtăși rețete tradiționale și povești legate de produsele românești. Prin intermediul acestor platforme, utilizatorii pot descoperi nu doar gusturile autentice, ci și semnificația culturală din spatele fiecărei preparate. În acest fel, blogurile devin un mediu de educație și conștientizare cu privire la bogata moștenire culinară românească.

De asemenea, blogurile contribuie la creșterea comunităților online, unde oamenii pot discuta despre experiențele lor, pot evalua produse și pot oferi recenzii. Aceasta interacțiune aduce un plus de valoare, deoarece specialiști în domeniu sau iubitori de gastronomie pot oferi perspective variate despre produsele românești. Astfel, utilizatorii pot lua decizii mai informate atunci când aleg să experimenteze diverse arome tradiționale.

În concluzie, blogurile nu doar că promovează produsele locale, dar și întăresc identitatea culturală a României. Ele funcționează ca un punte între generații, păstrând vii tradiții vechi și inspirând noi moduri de a le integra în viața de zi cu zi. Aceste platforme devin un instrument valoros pentru celebrarea diversității culinare și a tradițiilor românești.

Romania este o tara plina de traditii si gusturi autentice, iar produsele locale reprezinta o parte esentiala a identitatii noastre culturale. Fie ca este vorba despre branzeturi savuroase, mezeluri afumate sau dulceata facuta in casa, fiecare produs are o poveste care merita descoperita. In acest articol, ne propunem sa exploram impreuna cele mai delicioase produse romanesti, aducand in lumina reflectoarelor bloguri care se specializeaza in review-uri si recenzii, oferindu-ne pareri valoroase despre deliciile locale.

In cadrul blogului romanesc, gasim o multime de informatii utile despre produse traditionale, de la ingrediente si preparate la locuri de unde le putem achizitiona. Blogfest este un eveniment dedicat creatorilor de continut, iar participantii la aceasta manifestare aduc in prim-plan diverse perspective asupra gastronomiei romanesti. Prin intreaga sa varietate, blogul dedicat produselor ne invita sa ne conectam cu traditiile culinarilor noastre si sa apreciem valorile autentice ale gustului romanesc.

Cele Mai Populare Produse Locale

Romania este cunoscută pentru bogăția sa culinară, iar produsele locale sunt adevărate comori ale tradiției. Unul dintre cele mai reprezentative produse este brânza de burduf, un deliciu din lapte de oaie maturat în coji de brad. Aroma sa intensă și textura cremoasă o fac perfectă pentru a fi savurată alături de o țuică bună, ceva cu adevărat autentic românesc.

Un alt produs care nu poate lipsi dintr-o degustare românească este sarmalele. Acestea sunt preparate din carne tocată, orez și condimente, înfășurate în foi de varză sau viță de vie. Sarmalele sunt adesea servite cu smântână și mămăligă, devenind astfel un simbol al ospitalității românești, fiind preparate cu ocazia sărbătorilor și evenimentelor speciale.

Nu putem să nu menționăm și dulcețurile și conservele de fructe, care sunt parte integrantă a gastronomiei locale. Cele din mure și vișine sunt extrem de populare, aducând un gust vibrant și natural, perfect pentru a acompania o felie de pâine proaspătă sau pentru a îndulci o porție de clătite. Aceste produse reflectă nu doar bogăția fructelor de sezon, ci și tradiția preparării lor în gospodării.

Beneficiile Consumului de Produse Românești

Consumarea produselor românești contribuie la susținerea economiei locale. Atunci când alegem să cumpărăm de la fermieri, mici producători și comercianți locali, ajutăm la menținerea locurilor de muncă și la dezvoltarea comunităților noastre. Acest lucru nu numai că stimulează economia, dar și ajută la păstrarea tradițiilor și a culturii locale, care sunt esențiale pentru identitatea națională.

Un alt beneficiu important este calitatea superioară a produselor românești. Multe dintre acestea sunt cultivate sau produse folosind tehnici tradiționale, fără aditivi chimici sau conservanți. Astfel, consumatorii au parte de alimente proaspete, pline de nutrienți și gusturi autentice. Alegând să consumăm https://blogfest.ro/ , ne asigurăm că ceea ce mâncăm este nu doar sănătos, ci și plăcut pentru papilele noastre gustative.

In plus, produsele românești aduc o diversitate de arome și tradiții gastronomice, care reînvie cultura culinară a țării noastre. Există multe tipuri de bunuri, de la brânzeturi și mezeluri, la dulcețuri și vinuri, fiecare cu povestea și caracteristicile sale unice. Explorați aceste produse prin bloguri dedicate, recenzii și păreri, care ne ajută să descoperim și să apreciem gustul românesc.

Găsește Produse Locale Aproape de Tine

Pentru cei pasionați de gastronomie și dornici să descopere gustul românesc autentic, produsele locale reprezintă o adevărată comoară. Multe dintre acestea pot fi găsite în piețele tradiționale sau la magazinele de specialitate din orașele mari și din satele pitorești. De la brânzeturi fine, mezeluri artisanale și până la dulciuri preparate după rețete străvechi, fiecare produs spune o poveste despre zonele și comunitățile din care provine.

O modalitate excelentă de a descoperi aceste produse este să urmezi bloguri românești dedicare alimentelor locale. Blogurile de tip review oferă păreri detaliate despre diverse produse, recomandând cele mai bune locuri de unde poți achiziționa bunătățile autohtone. Participarea la evenimente precum BlogFest sau Blog Fest poate oferi oportunitatea de a interacționa direct cu producătorii și de a putea degustă o varietate de produse care reflectă diversitatea culinară a României.

Nu uita că multe dintre aceste produse pot fi comandate și online, datorită dezvoltării comerțului electronic. Căutând bloguri recenzii și păreri, vei găsi adesea informații utile despre livrare și disponibilitate, salvându-te de efortul de a te deplasa. Descoperind aceste comori locale, nu doar că îti satisfaci papilele gustative, dar și sprijini economia locală și tradițiile culinare din România.

For ODMP, PO vs. PR, respectively, Cmax was 30.9 ± 10.4 vs. 8.8 ± 4.8, Tmax was 3.2 ± 1.6 vs. 1.7 ± 1.1, and t1/2 was 5.0 ± 2.7 vs. 8.3 ± 4.8, with AUC of 167.8 ± 36.2 vs. 50.1 ± 19.2 and F of 28 ± 6. The differences between PO and PR were significant (P less then 0.03) for AUC and Cmax for both PIM and ODMP. Conclusions and Clinical Relevance The pharmacokinetics of PIM and ODMP were described following PO and PR administration. The findings suggest that pimobendan PR might achieve effective concentrations and, as such, warrant future studies of clinical effectiveness in treating dogs with congestive heart failure and which are unable to receive medication PO.Over the last 20 years, substantial knowledge has been developed in Veterinary oncology, and tumors previously reported only in humans have been identified in animals. Primary paragangliomas of the tongue are extremely rare tumors in human beings and have never been reported in animals. A Chow Chow dog showed an ulcerated nodule at the lingual body, deeply infiltrated, which extended to the base of the tongue. A full clinical and pathological investigation was conducted, and a post-surgical follow-up of 6 months did not detect recurrence. Cytological, histological, and immunohistochemical features are presented and support the diagnosis of lingual paraganglioma. The paraganglioma of the tongue reported in this Chow Chow dog shares many similarities with the human counterpart.This study investigated the in vitro effects of Greek oregano and garlic essential oils on inhibition of Eimeria parasites and their in vivo effects on production performance, intestinal bacteria counts, and oocyst output. An inhibition assay was performed in vitro using Eimeria tenella Wisconsin strain sporozoites and Madin-Darby bovine kidney (MDBK) cells. Intracellular sporozoite invasion was quantified by detection of E. tenella DNA using qPCR from cell monolayers harvested at 2 and 24 h post-infection. Parasite invasion was inhibited by the oregano essential oil at the concentration of 100 μg/ml by 83 or 93% after 2 or 24 h, respectively. Garlic essential oil reached a maximum inhibition of 70% after 24 h with the 50 μg/ml concentration. Normal morphology was observed in MDBK cells exposed to concentrations of 100 μl/ml of garlic or oregano for over 24 h. In the in vivo trial, 180 male broiler chicks (45.3 ± 0.7 g) were allocated into two treatments (6 pens of 15 chicks per treatment). Control treatment 5 vs. 2.882 CFU/g; p less then 0.01). In conclusion, the combined supplementation of oregano and garlic essential oils had a potent anticoccidial effect in vitro and a growth-promoting effect in broilers reared in the absence of anticoccidial drugs.This study was conducted to evaluate effects of the single and combined use of curcumin (CUR) and piperine (PIP) on performance, intestinal barrier function, and antioxidant capacity of weaned piglets. A total of 50 Wuzhishan piglets weaned at 35 days of age were randomly assigned to five groups receiving a corn-soybean basal diet (CON), the basal diet supplemented with 50 mg/kg piperine, 200 mg/kg curcumin (low-CUR), 200 mg/kg curcumin + 50 mg/kg piperine (PIP + CUR), and 300 mg/kg curcumin (high-CUR), respectively. The results showed that the feed/gain ratio (F/G) and plasma d-lactate and diamine oxidase activity (DAO) of the CUR + PIP and high-CUR groups were lower than those of the CON group (all P 0.05). In conclusion, the combination of CUR and PIP seemed to be as advantageous as high-CUR to piglets, but it was more effective than the single use of CUR and PIP. These data indicated that the basal diet supplemented with CUR + PIP or high-CUR could improve the intestinal permeability and suppress oxidative stress of weaned Wuzhishan piglets.Up to 60% of neonates can be affected by gastroenteritis due to specific pathogens or aspecific polymicrobial interactions. The present study evaluated if a dietary supplementation with MOS, FOS, E. faecium and L. acidophilus in pregnancy may reduce gastroenteritis in puppies. Fifteen Great Danes were divided in 3 groups. The control group (CG) ate a standard diet. In 2 study groups, the diet was supplemented with pre- and probiotics during the last (1WG) and the last 4 pregnancy weeks (4WG). Up to 9 weeks, puppies were checked daily to identify first- or second- presentation gastroenteritis. Data were processed by χ2 (P less then 0.05). First-presentation gastroenteritis was more frequent in CG than in 1WG than in 4WG. Second-presentation gastroenteritis was more frequent in CG than in 1 and 4WG. Puppies from pre- and probiotics supplemented bitches were less prone to gastroenteritis. 1 or 4WG equally reduced second-presentation gastroenteritis in puppies, but 4WG was better than 1WG on first-presentation gastroenteritis. By entero-mammary link, supplemented bitches produced higher immune quality colostrum, thus puppies faced immunitary challenges better; moreover, maternal microbiota, positively altered by supplementation, was transferred to newborns, becoming more resistant to gastroenteritis. This information can be useful in clinical practice with the goal of preventing gastroenteritis in puppies and reducing its prevalence and severity.The objective of this study was to compare virulence and resistance factors of mucosal and cutaneous staphylococci from dogs with pyoderma in the UK and Romania, two countries with different approaches to antimicrobial use in companion animals. Staphylococcal isolates (n = 166) identified to the species level as being Staphylococcus pseudintermedius or coagulase negative (CoNS) were analyzed for their antimicrobial resistance (AMR) profile and presence of resistance and virulence genes. Of the investigated isolates, 26 were methicillin-resistant S. pseudintermedius (MRSP), 89 were methicillin-susceptible S. pseudintermedius (MSSP) and 51 were coagulase negative staphylococci (CoNS). https://www.selleckchem.com/products/CP-690550.html A significantly larger number of isolates originating from Romania were resistant to clindamycin, tetracycline, and chloramphenicol compared to the UK isolates (P less then 0.05). Resistance to amoxicillin-clavulanic acid, gentamicin, and trimethoprim-sulphamethoxazole was more evident in UK isolates. Fusidic acid resistance was common in Staphylococcus spp.

The T329S mutation in flavin-containing monooxygenase 3 (FMO3) impairs the trimethylamine (TMA) metabolism in laying hens. The TMA metabolic pathway is closely linked to lipid metabolic diseases, such as atherosclerosis and fatty liver disease. We aimed to evaluate the effects of the T329S mutation in FMO3 on lipid metabolism in chickens during the late laying period. We selected 18 FMO3 genotyped individuals (consisting of six AA, six AT, and six TT hens) with similar body weight and production performance. The lipid metabolism and deposition characteristics of the laying hens with different genotypes were compared. The T329S mutation moderated the serum-lipid parameters in TT hens compared to those in AA and AT hens from 49 to 62 weeks. Furthermore, it reduced the serum trimethylamine N-oxide concentrations and increased the serum total bile acid (p less then 0.05) and related lipid transporter levels in TT hens. Moreover, it significantly (p less then 0.01) decreased atherosclerotic lesions and hepatic steatosis in TT hens compared to those in the AA and AT hens. Our findings may help improve the health status in laying hens during the late laying period.Free-range systems are considered to improve bird health and welfare, thereby satisfying consumer demands. Behavioral time budget, fear level and clinical welfare indicators were compared for two Turkish laying hen genotypes, Atak-S (brown) and Atabey (white), reared in a free-range system. A total of 420 laying hens (210 Atak-S, 210 Atabey) were studied between 19 and 72 weeks of age. Higher percentages of eating and drinking behavior, feather pecking, and explorative pecking were observed for Atak-S hens, whereas Atabey hens were preening, walking-standing, and resting more. The duration of tonic immobility was longer, and the number of inductions was lower in Atabey compared with Atak-S hens. Atabey hens had less keel bone damages and better plumage conditions on the breast, wing, and tail at 56 and 72 weeks of age than Atak-S hens. Footpad dermatitis was more common in Atabey hens at 40 weeks, whereas Atak-S hens had a higher prevalence of footpad dermatitis with moderate lesions at 72 weeks of age. These findings indicate that free-range Atak-S hens may be more prone to keel bone damage and development of feather pecking, but they showed less foot lesions and were less fearful.Recently developed myostatin (MSTN) mutant quail and chickens demonstrated similar effects of MSTN on muscle and fat developments between avian and mammalian species. However, the effect of MSTN mutation on the quality of eggshells, an important avian specific characteristic, has not yet been investigated although egg production traits of mutant quail have been studied. In this study, several parameters for eggshell quality, including eggshell size, eggshell weight, eggshell breaking strength (EBS), and eggshell thickness, were all compared between MSTN mutant and wild-type (WT) eggs. MSTN mutant eggs had greater height and width along with heavier eggshell weight compared to WT eggs, which shows proportional improvement in egg size as affected by the MSTN mutation. However, EBS and eggshell thickness were decreased in mutant eggs compared to WT eggs. https://www.selleckchem.com/products/pf-07220060.html In addition, the palisade layer, the thickest and most important layer for the strength of an eggshell, was also decreased without a change in the number of vesicular holes. These data indicated that decreases in the thickness of the eggshell and the palisade layer would be a main factor contributing to a lower EBS in mutant eggs. MSTN mutant quail provide a useful model to better understand the function of MSTN on avian uterine cell development and eggshell biomineralization.The goose is a popular poultry species, and in the past two decades the goose industry has become highly profitable across the globe. Ganders low reproductive performance remains a barrier to achieving high fertility and hatchability in subsequent flocks. To address the global demand for cheaper animal protein, various methodologies for improving avian (re)production should be explored. A large amount of literature is available on reproduction traits and techniques for commercial chicken breeder flocks, while research on improved reproduction in ganders has been carried out to a lesser extent. The present review aims to provide a comprehensive literature overview focusing on recent advancements/techniques used in improving gander reproductive efficacy in the context of ensuring a globally sustainable goose industry.Bacterial contamination of boar semen occurs with some frequency in artificial insemination centers and may have a negative effect on the quality of the semen as well as on the sows' reproductive capacity. Normally, the source of bacterial contamination in pig seminal doses is the own boar. However, distilled water or laboratory equipment used to elaborate the seminal doses can be an important source of bacterial contamination. This study focused on the identification of gram-negative bacteria in boar semen, and impact on the quality of ejaculates obtained from boar, as well as on the establishment of antimicrobial resistance patterns of isolated gram-negative bacteria. Semen samples were collected from 96 boars, ranging in age from 12-36 month, from three artificial insemination centers from the North-West of Romania. Bacterial species were identified by two methods matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and API 20 E (BioMerieux, France). The main bacteria isolated from the doses diluted semen were gram-negative bacteria (47.91%), with a majority of the contaminant bacteria belonging to the family Enterobacteriaceae Seratia marcescens 19.56%, Proteus mirabilis 15.21% and Escherichia coli 10.86% and to the family Pseudomonaceae Ralstonia picketii 17.39%, Burkholderia cepacia 10.86%, Pseudomonas aeruginosa 8.69%, and Pseudomonas fluorescens 4.34%, respectively. More than half of these isolates (56.52%) were resistant to gentamycin and 58.69% were resistant to penicillin. These antibiotics are very frequently added in sperm diluent in the centers for the processing of sperm from boars in Romania. Regular monitoring for bacterial contamination is an important aspect of a control program.Moringa is widely known as a plant with high medicinal properties. Therefore, moringa has a high potential for use as an immunostimulant in shrimp. This study investigated the effect of a moringa water extract on the immune response, resistance against V. alginolyticus, and growth performance of whiteleg shrimp. To perform the in vitro assay, hemocytes were incubated with different concentrations of the moringa extract. Furthermore, the moringa extract was incorporated at 0 (control), 1.25 g (ME1.25), 2.5 g (ME2.5), and 5.0 g (ME5.0) per kg of diet for the in vivo assay. During the rearing period, immune responses, namely the total hemocyte count (THC), phenoloxidase (PO) activity, phagocytosis activity, superoxide anion production, and immune-related gene expression were examined on days 0, 1, 2, 4, 7, 14, 21, and 28. Growth performance was measured 60 days after the feeding period. Furthermore, the shrimp were challenged with V. alginolyticus after being fed for different feeding durations. The results of tresistance against V. alginolyticus infection.Copy number variation (CNV) can affect gene function and even individual phenotypic traits by changing the transcription and translation level of related genes, and it also plays an important role in species evolution. Chloride voltage-gated channel 2 (CLCN2) encodes a voltage-gated chloride channel (CLC-2), which has a wide organ distribution and is ubiquitously expressed. Based on previous studies, we hypothesize that CLCN2 could be a candidate gene involved in cell volume regulation, transepithelial transport and cell proliferation. This study aimed to explore CNVs in the CLCN2 gene and investigate its association with growth traits in four Chinese cattle breeds (Yunling cattle, Xianan cattle, Qinchuan cattle and Pinan cattle). We identified there are two copy number variation regions (CNV1 3600 bp, including exon 2-11; CNV2 4800 bp, including exon 21-22) of the CLCN2 gene. The statistical analysis showed that the CNV1 mutation in the YL cattle population was significantly associated with cannon circumference (p less then 0.01). The CNV2 mutation in the XN cattle population had a significant effect on body slanting length, chest girth and body weight (p less then 0.05). In the YL cattle, the association analysis of CLCN2 gene CNV1 and CNV2 combination with cannon circumference was significant (p less then 0.01). Our results provide evidence that CNV1 and CNV2 in CLCN2 are associated with growth traits in two different cattle populations and could be used as candidate markers for cattle molecular breeding.The Murciano-Granadina goat breed has been described as a slow milking breed. As milking machine parameters can affect milk extraction in terms of yield and time employed, two experiments of one-month duration were performed with 88 goats in Latin square design to find the best combination of these parameters. One of them was carried out in a mid-line milking machine and one in a low-line milking machine. For each of them, two vacuum levels (36 and 40 kPa), two pulsation rates (90 and 120 cycles/min) and two pulsator ratios (50 and 60%) were used and milking efficiency, sanitary status of the mammary gland, milk cortisol, and teat end status were evaluated. Results showed that in milking machines installed in mid- and low-line, the use of 40 kPa system vacuum, 60% pulsator ratio and 90 or 120 cycles/min pulsation rate achieved optimum milking fractioning and efficiency. In the case of low-level milking machines, a similar combination with 36 kPa not only showed worse milking fractioning values, but also provided better values of teat end status and cortisol level.This study investigated the effects of Goji berry (Lycium barbarum) dietary supplementation during pregnancy on insulin sensitivity of rabbit does and their offspring. Starting from two months before the artificial insemination, 75 New Zealand White does were fed only commercial standard diet (C) or supplemented with 1% (G1) and 3% (G3) of Goji berries. Their offspring received a standard diet but kept the nomenclature of the mother's group. Fasting and intravenous glucose tolerance test-derived indices were estimated at 21 days of pregnancy on rabbit does and at 90 days of age on the offspring. No difference was found in the fasting indices, while the diet modulated the response to glucose load of rabbit does. In particular, G3 group had the lowest glucose concentrations 5 min after the bolus administration (p less then 0.05) and, as a result, differed in the parameters calculated during the elimination phase such as the elimination rate constant (Kel), the half-life of the exogenous glucose load (t1/2), and apparent volume of distribution (Vd; for all, p less then 0.05). The high dose of Goji supplementation could thus enhance the first-phase glucose-induced insulin secretion. Findings on the offspring were inconsistent and therefore a long-term effect of Goji supplementation during pregnancy could not be demonstrated. Further study on the effect of Goji on the secretory pathway of insulin could clarify its hypoglycaemic action, while different protocols are needed to investigate its potential effects on foetal programming.

Periodontal disease is an inflammatory, dysbiotic condition. Studies have shown that in the elderly, periodontal disease was associated with cognitive dysfunction and Alzheimer's disease.

To investigate whether young healthy subjects with periodontal disease have lower cognition compared to those without periodontal disease. The salivary cytokines (IL-1β, TNF-α) levels in relation to cognition were also tested.

In a monocenter, cross-sectional study, forty subjects [mean age (SD) = 34 (5) and 48% female] from western Romania were classified into periodontal disease conditions using radiographic assessment 10 subjects had aggressive periodontitis (AGG_P), 20 chronic mild-moderate periodontitis (CR_P), and 10 no periodontitis (NL_P). Neuropsychological assessment performed by standardized neurologists and psychologist included Rey Auditory Verbal Learning Test (RAVLT), Montreal Cognitive Assessment test (MOCA), Mini-Mental State Examination (MMSE), and Prague tests. Salivary cytokines levels were determined by ELISA.

RAVLT and MOCA delayed recall scores were lower in AGG_P group compared to NL_P and CR_P. The learning curve was also different with subjects with AGG_P showing reduced learning performance. Contrary to our hypothesis, salivary IL-1β associated with immediate but not delayed cognitive scores.

These results showed for the first time that subjects with AGG_P had cognitive dysfunction and IL-1β may play a role in this process.
These results showed for the first time that subjects with AGG_P had cognitive dysfunction and IL-1β may play a role in this process.Adolescent sleep research has focused heavily on duration and quality with less work examining chronotype, defined as individual differences in sleep-wake timings driven by the circadian rhythm. This study filled a gap in the literature by utilizing actigraphy-based sleep estimates in an accelerated longitudinal design in order to better understand the developmental trajectory and individual stability of chronotype during adolescence, as well as the associations between chronotype with risky behaviors, substance use, and depressive symptoms. A total of 329 adolescents (57% female; 21% Asian American, 31% European American, 41% Latino, 7% other ethnicity) provided actigraphy-based estimates of sleep and completed questionnaires at up to three time points, two years apart, beginning at 14-17 years of age. Multilevel modeling revealed a non-linear developmental trend in chronotype whereby eveningness increased from 14 to 19 years of age followed by a trend toward morningness. Individual differences in chronotype exhibited modest stability during adolescent development. Furthermore, greater evening chronotype was associated with more risky behaviors and substance use among males, and more substance use among older adolescents, whereas depressive symptoms were not associated with chronotype. The findings from this study may have practical implications for adolescent behavioral health interventions targeted at reducing risky behaviors and substance use among youth.Strong school engagement is crucial for school success among adolescents and particularly important for reducing recidivism. Yet, little is known about school engagement among youth serving probation while attending community schools. This study tested the multivariate associations between risk and promotive factors with three components of school engagement (behavioral, cognitive, and emotional). The study's sample was derived from 5,378 intake assessments (23.6% female) of youth entering juvenile probation in a Pacific Northwest county who were assessed as either moderate or high risk for recidivism. The racial composition of the sample was predominantly White or European American (56.0%) and Black or African American (24.2%) and ranged in age from 10 to 19 years old (M = 15.5, SD = 1.46). The results suggest that dimensions of school engagement can be strengthened by increased relational and skill-building supports throughout youth's social ecologies. https://www.selleckchem.com/products/danirixin.html The promotive factors of prosocial attitudes and prosocial community connections were significantly associated with increased school engagement. The implications of these findings are discussed regarding opportunities and strategies that promote school engagement for youth on probation.Limited research has investigated factors that shape White youth's civic action aimed at social change. Investigating the relation between Whiteness and civic action is an essential step toward identifying and cultivating environments that encourage White youth to use their racial privilege to combat inequality through civic engagement. To address this gap in the literature, across two distinct samples, this study investigates the role of White guilt in motivating civic action and the moderating role of civic beliefs. Participants included all young adults who self-identified as White from two online survey studies (Study 1, N = 219 college students, 71.9% Women, 28.1% Men, mean age = 19.6; Study 2, N = 185, 50% current college students, 54.6% Women, 45.4% Men, mean age = 23.9). In Study 1, White guilt related to more civic action. In the context of high social responsibility, White guilt related to more civic action; in the context of low social responsibility, White guilt corresponded with less civic action. In Study 2, White guilt also related to more civic action, and civic efficacy emerged as a potential moderator. Collectively, these results highlight the potential for White guilt to be turned into meaningful civic action, particularly when coupled with civic beliefs.Retinitis pigmentosa (RP) is a blinding eye disease affecting nearly two million people worldwide. Dogs are affected with a similar illness termed progressive retinal atrophy (PRA). Lapponian herders (LHs) are affected with several types of inherited retinal dystrophies, and variants in PRCD and BEST1 genes have been associated with generalized PRA and canine multifocal retinopathy 3 (cmr3), respectively. However, all retinal dystrophy cases in LHs are not explained by these variants, indicating additional genetic causes of disease in the breed. We collected DNA samples from 10 PRA affected LHs, with known PRCD and BEST1 variants excluded, and 34 unaffected LHs. A genome-wide association study identified a locus on CFA20 (praw = 2.4 × 10-7, pBonf = 0.035), and subsequent whole-genome sequencing of an affected LH revealed a missense variant, c.3176G>A, in the intraflagellar transport 122 (IFT122) gene. The variant was also found in Finnish Lapphunds, in which its clinical relevancy needs to be studied further.