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Therapeutic proteins (Biologics/Biotherapeutics) are active biomolecules are derived from a biological source by production in microorganisms or cells (humans and animals) using biotechnology.

Protein therapeutics exhibit complex secondary and tertiary structures that must be maintained to exhibit the desired function. Protein therapeutics cannot be completely synthesized by chemical processes and have to be manufactured in living cells or organisms; consequently, the choices of the cell line, species origin, and culture conditions all affect the final product characteristics. Moreover, most biologically active proteins require posttranslational modifications that can be compromised when heterologous expression systems are used. Additionally, as the products are synthesized by cells or organisms, complex purification processes are involved. Furthermore, viral clearance processes such as removal of virus particles with filters or resins, as well as inactivation steps by changing pH or detergents, are implemented to prevent the serious safety issue of viral contamination of protein drug substances.
More info:https://therapeutic.creativebiomart.net/product-type.html

07/06/2023

Conjugation and Labeling Services market 2023 – Industry Growth by 2035

The complexities associated with conjugation of biomolecules and the need for click-chemistry expertise have prompted the pharmaceutical industry to rely on conjugation and labeling service providers

Roots Analysis is pleased to announce the publication of its recent study, titled, “Conjugation and Labeling Services Market, 2023-2035”

The study presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain, across different geographies. Amongst other elements, the report includes

 An executive summary of the insights captured during our research. It offers a high-level view on the current state of conjugation and labeling services market and its likely evolution in the mid-long term.
 A general overview of conjugation and labeling of biomolecules, highlighting the various advantages of biomolecule conjugation and labeling. It also provides details on the different types of biomolecular conjugates and labels.
 A detailed assessment of the overall market landscape of the companies offering conjugation and labeling services.
 A company competitiveness analysis of conjugation and labeling service providers.
 Elaborate profiles of prominent players offering conjugation and labeling services (shortlisted based on a proprietary criterion).
 A detailed analysis of the recent partnerships inked between stakeholders engaged in this domain, since 2018.
 A detailed analysis of recent events (webinars / conferences / seminars / meetings / symposiums / summits) that were organized for stakeholders in the bioconjugation domain.
 A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
 Type of Molecule
 Proteins
 Peptides
 Small Molecules
 Antibodies
 Other Molecules

 Type of Molecular Conjugate / Label
 Polymers
 Haptens
 Enzymes
 Fluorescent Tags
 Bead Coupling / Particle Conjugates
 Quantum Dots
 Isotopes
 Other Molecular Conjugates / Labels

 Key Geographical Regions
 North America
 Europe
 Asia-Pacific
 Middle East and North Africa
 Latin America

Key companies covered in the report
 AltaBioscience
 Bachem
 Bio-Synthesis
 Cayman Chemical
 CliniSciences
 Eurogentec
 GBI
 Mimotopes
 Peptide Institute
 piCHEM

For additional details, please visit https://www.rootsanalysis.com/reports/conjugation-and-labeling-services-market.html

News article
Biopharmaceutical Filtration Market

Learn from experts: do you know about these emerging industry trends?
T-cell Immunotherapies: The Future of Modern Cancer Treatments
Antiviral Drugs Development: Are we Prepared for the Next Viral Pandemic?

Learn from our recently published whitepaper: -
Next Generation Biomanufacturing – The Upcoming Era of Digital Transformation

About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Learn more about Roots Analysis consulting services:
Roots Analysis Consulting - the preferred research partner for global firms

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Conjugation services and Labeling Services Market, driven by the presence of nearly 250 companies registering ~30 M&As, is anticipated to grow at 10% CAGR in the coming decade

www.rootsanalysis.com

06/11/2023

Katherine Watt "Library" and Believe It or Not....
By Anna Von Reitz


There are certain of those among us whose work I follow, and Katherine Watt is one of them. She has been working tirelessly on issues that run a wide gamut of inter-related interest: church and state relations, the history and nature of the bioweapons recently deployed, and the legal matrix surrounding both.

For those of you who want a deep, incisive, and timely dive, go here:
https://substack.com/@bailiwicknews and start browsing. This is the free version link. There is also a paid version to help support her work.

Katherine describes herself as a "Gen-X Catholic" and so when she focuses on the history of religion, politics, etc., she comes at it from a Catholic background. Don't let that stop you. That is actually helpful, because so much of what we take for granted, both good and bad, has its genesis either in the Church or as a result of Church interactions with government or the Church acting as a government.

Katherine's writing won't be everyone's cup of tea. She's academic by nature and to the bone, so her approach is rigorous, her subject matter is daunting, and she is often at pains to provide what she called "orientation for new readers" --- trying to bring people up to speed.

Still, like a slice of mental cheesecake, you will be rewarded for making the effort to read Katherine's material. She never takes you on a wild goose chase and doesn't belabor her presentation.

I do not recommend John Curren Chapman's "work" overall, mainly because he so often gets lost in suppositions and arcana, but, at the same time, he occasionally digs up bones that are truly worthwhile.

Here's some meat from his fork, extracted:

Question: Do self-assembling nano-particles in the form of graphene exist?

Answer: Yes, self-assembling nanoparticles in the form of graphene do exist. For example, scientists have shown that colloidally synthesized zero-dimensional gold nanoparticles of various sizes can be deterministically self-assembled in highly-ordered, anisotropic, non-close-packed, multi-scale morphologies with templates designed from instability-driven, deformed 2D nanomaterials1. Another example is the ultra-fast self-assembly and stabilization of reactive nanoparticles in reduced graphene oxide films.

Question: Is it possible for nano particles to enter the body of an animal and affect/effect the RNA/DNA relationships of the animal?

Answer: Yes, it is possible for nanoparticles to enter the body of an animal and affect its RNA/DNA relationships. When nanoparticles come into the vicinity of the cellular system, chances of uptake become high due to their small size. This cellular uptake of nanoparticles enhances its interaction with DNA, leading to structural and functional modification into the DNA1. For example, nanomaterials for nucleic acid delivery offer an unprecedented opportunity to overcome drawbacks; owing to their tunability with diverse physico-chemical properties, they can readily be functionalized with any type of biomolecules/moieties for selective targeting.

Question: Is it possible for nanoparticles to be managed or manipulated through the use of 5G radio frequencies?

Answer: No information found.

Question: What outside energy can control the self assembly process of graphene nanoparticles?

Answer: One way to control the self-assembly process of graphene nanoparticles is through the use of an electric field. For example, an alternating-current electric field can be used to align stacks of graphene nanoparticles and identify the control parameters of chain-formation in an epoxy polymer1. Another way is through electrostatic interactions between nanoparticles, which can reinforce the superstructure and regulate the assembly in the form of attractive or repulsive force. The rational design and control of interparticle electrostatic forces can help achieve effective self-assembly.

[So, although there is no information available in the scientific literature databases he consulted on the effect of 5G on the self-assembly process of graphene nano-particles per se, there is plenty of information about more generalized electro-magnetic effects.]

Question: Is it scientifically possible for anyone to inject nano particles into a human bloodstream?

Answer: Yes, it is scientifically possible to inject nanoparticles into the human bloodstream. In fact, some vaccines rely on a nanoparticle delivery system 1. Injected nanoparticles usually end up in the organs that filter blood—liver, spleen, bone marrow and kidney 1. Nanoparticles can also be used for drug delivery and other medical applications.

Question: Does 5G technology generate an electric field?

Answer: Yes, 5G technology produces a type of energy called electromagnetic radiation which creates an area called an electromagnetic field (EMF)1. Electromagnetic field measurements in 5G networks are necessary to prove that the maximum radiation is below a certain country-specific threshold.
-------

End of quoted materials --- this last Answer (above) relates directly to my prior inserted comment. If electric fields in general can have effects on the self-assembly of graphene nano-particles, it is given that the electromagnetic field from 5G radiation could have an effect.

So, connect the dots, folks.

He gave the following links as resources:

nature.com
nature.com
onlinelibrary.wiley.com
pubs.rsc.org
frontiersin.org
nature.com
nihrecord.nih.gov
pubs.acs.org
sciencedaily.com
arxiv.org
theverge.com
nature.com

----------------------------

See this article and over 4200 others on Anna's website here: www.annavonreitz.com

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People

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Posts

Therapeutic proteins (Biologics/Biotherapeutics) are active biomolecules are derived from a biological source by production in microorganisms or cells (humans and animals) using biotechnology.

Protein therapeutics exhibit complex secondary and tertiary structures that must be maintained to exhibit the desired function. Protein therapeutics cannot be completely synthesized by chemical processes and have to be manufactured in living cells or organisms; consequently, the choices of the cell line, species origin, and culture conditions all affect the final product characteristics. Moreover, most biologically active proteins require posttranslational modifications that can be compromised when heterologous expression systems are used. Additionally, as the products are synthesized by cells or organisms, complex purification processes are involved. Furthermore, viral clearance processes such as removal of virus particles with filters or resins, as well as inactivation steps by changing pH or detergents, are implemented to prevent the serious safety issue of viral contamination of protein drug substances.
More info:https://therapeutic.creativebiomart.net/product-type.html

07/06/2023

Conjugation and Labeling Services market 2023 – Industry Growth by 2035

The complexities associated with conjugation of biomolecules and the need for click-chemistry expertise have prompted the pharmaceutical industry to rely on conjugation and labeling service providers

Roots Analysis is pleased to announce the publication of its recent study, titled, “Conjugation and Labeling Services Market, 2023-2035”

The study presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain, across different geographies. Amongst other elements, the report includes

 An executive summary of the insights captured during our research. It offers a high-level view on the current state of conjugation and labeling services market and its likely evolution in the mid-long term.
 A general overview of conjugation and labeling of biomolecules, highlighting the various advantages of biomolecule conjugation and labeling. It also provides details on the different types of biomolecular conjugates and labels.
 A detailed assessment of the overall market landscape of the companies offering conjugation and labeling services.
 A company competitiveness analysis of conjugation and labeling service providers.
 Elaborate profiles of prominent players offering conjugation and labeling services (shortlisted based on a proprietary criterion).
 A detailed analysis of the recent partnerships inked between stakeholders engaged in this domain, since 2018.
 A detailed analysis of recent events (webinars / conferences / seminars / meetings / symposiums / summits) that were organized for stakeholders in the bioconjugation domain.
 A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
 Type of Molecule
 Proteins
 Peptides
 Small Molecules
 Antibodies
 Other Molecules

 Type of Molecular Conjugate / Label
 Polymers
 Haptens
 Enzymes
 Fluorescent Tags
 Bead Coupling / Particle Conjugates
 Quantum Dots
 Isotopes
 Other Molecular Conjugates / Labels

 Key Geographical Regions
 North America
 Europe
 Asia-Pacific
 Middle East and North Africa
 Latin America

Key companies covered in the report
 AltaBioscience
 Bachem
 Bio-Synthesis
 Cayman Chemical
 CliniSciences
 Eurogentec
 GBI
 Mimotopes
 Peptide Institute
 piCHEM

For additional details, please visit https://www.rootsanalysis.com/reports/conjugation-and-labeling-services-market.html

News article
Biopharmaceutical Filtration Market

Learn from experts: do you know about these emerging industry trends?
T-cell Immunotherapies: The Future of Modern Cancer Treatments
Antiviral Drugs Development: Are we Prepared for the Next Viral Pandemic?

Learn from our recently published whitepaper: -
Next Generation Biomanufacturing – The Upcoming Era of Digital Transformation

About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Learn more about Roots Analysis consulting services:
Roots Analysis Consulting - the preferred research partner for global firms

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

Conjugation services and Labeling Services Market, driven by the presence of nearly 250 companies registering ~30 M&As, is anticipated to grow at 10% CAGR in the coming decade

www.rootsanalysis.com

06/11/2023

Katherine Watt "Library" and Believe It or Not....
By Anna Von Reitz


There are certain of those among us whose work I follow, and Katherine Watt is one of them. She has been working tirelessly on issues that run a wide gamut of inter-related interest: church and state relations, the history and nature of the bioweapons recently deployed, and the legal matrix surrounding both.

For those of you who want a deep, incisive, and timely dive, go here:
https://substack.com/@bailiwicknews and start browsing. This is the free version link. There is also a paid version to help support her work.

Katherine describes herself as a "Gen-X Catholic" and so when she focuses on the history of religion, politics, etc., she comes at it from a Catholic background. Don't let that stop you. That is actually helpful, because so much of what we take for granted, both good and bad, has its genesis either in the Church or as a result of Church interactions with government or the Church acting as a government.

Katherine's writing won't be everyone's cup of tea. She's academic by nature and to the bone, so her approach is rigorous, her subject matter is daunting, and she is often at pains to provide what she called "orientation for new readers" --- trying to bring people up to speed.

Still, like a slice of mental cheesecake, you will be rewarded for making the effort to read Katherine's material. She never takes you on a wild goose chase and doesn't belabor her presentation.

I do not recommend John Curren Chapman's "work" overall, mainly because he so often gets lost in suppositions and arcana, but, at the same time, he occasionally digs up bones that are truly worthwhile.

Here's some meat from his fork, extracted:

Question: Do self-assembling nano-particles in the form of graphene exist?

Answer: Yes, self-assembling nanoparticles in the form of graphene do exist. For example, scientists have shown that colloidally synthesized zero-dimensional gold nanoparticles of various sizes can be deterministically self-assembled in highly-ordered, anisotropic, non-close-packed, multi-scale morphologies with templates designed from instability-driven, deformed 2D nanomaterials1. Another example is the ultra-fast self-assembly and stabilization of reactive nanoparticles in reduced graphene oxide films.

Question: Is it possible for nano particles to enter the body of an animal and affect/effect the RNA/DNA relationships of the animal?

Answer: Yes, it is possible for nanoparticles to enter the body of an animal and affect its RNA/DNA relationships. When nanoparticles come into the vicinity of the cellular system, chances of uptake become high due to their small size. This cellular uptake of nanoparticles enhances its interaction with DNA, leading to structural and functional modification into the DNA1. For example, nanomaterials for nucleic acid delivery offer an unprecedented opportunity to overcome drawbacks; owing to their tunability with diverse physico-chemical properties, they can readily be functionalized with any type of biomolecules/moieties for selective targeting.

Question: Is it possible for nanoparticles to be managed or manipulated through the use of 5G radio frequencies?

Answer: No information found.

Question: What outside energy can control the self assembly process of graphene nanoparticles?

Answer: One way to control the self-assembly process of graphene nanoparticles is through the use of an electric field. For example, an alternating-current electric field can be used to align stacks of graphene nanoparticles and identify the control parameters of chain-formation in an epoxy polymer1. Another way is through electrostatic interactions between nanoparticles, which can reinforce the superstructure and regulate the assembly in the form of attractive or repulsive force. The rational design and control of interparticle electrostatic forces can help achieve effective self-assembly.

[So, although there is no information available in the scientific literature databases he consulted on the effect of 5G on the self-assembly process of graphene nano-particles per se, there is plenty of information about more generalized electro-magnetic effects.]

Question: Is it scientifically possible for anyone to inject nano particles into a human bloodstream?

Answer: Yes, it is scientifically possible to inject nanoparticles into the human bloodstream. In fact, some vaccines rely on a nanoparticle delivery system 1. Injected nanoparticles usually end up in the organs that filter blood—liver, spleen, bone marrow and kidney 1. Nanoparticles can also be used for drug delivery and other medical applications.

Question: Does 5G technology generate an electric field?

Answer: Yes, 5G technology produces a type of energy called electromagnetic radiation which creates an area called an electromagnetic field (EMF)1. Electromagnetic field measurements in 5G networks are necessary to prove that the maximum radiation is below a certain country-specific threshold.
-------

End of quoted materials --- this last Answer (above) relates directly to my prior inserted comment. If electric fields in general can have effects on the self-assembly of graphene nano-particles, it is given that the electromagnetic field from 5G radiation could have an effect.

So, connect the dots, folks.

He gave the following links as resources:

nature.com
nature.com
onlinelibrary.wiley.com
pubs.rsc.org
frontiersin.org
nature.com
nihrecord.nih.gov
pubs.acs.org
sciencedaily.com
arxiv.org
theverge.com
nature.com

----------------------------

See this article and over 4200 others on Anna's website here: www.annavonreitz.com

Li Yuan - Novel probe helps to detect deep sea biological macromolecules:

https://phys.org/news/2023-03-probe-deep-sea-biological-macromolecules.html

#RamanScattering #InsertionProbe #RiPSERS #AcetylCoA #βCarotene #AminoAcids #BiologicalMacromolecules #CAS #Spectroscopy #DeepSea #SeepVents #Biomolecules #Biology #Oceanology