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12/09/2024


Revision surgeries were not required in the primary group. In the secondary group, there was 1 revision due to deep infection, and 3 other patients required dorsal plate removal. Excluding plate removal, the Kaplan-Meier survival at 3 years was not significantly different between groups (
= .775).

Although arthrodesis of the first MTP joint was an effective procedure for hallux rigidus, the clinical outcomes in patients who had prior hallux valgus surgery were worse than those for patients who underwent primary surgery for hallux rigidus.

Level III, retrospective cohort study.
Level III, retrospective cohort study.
To evaluate outcomes, healthcare resource utilization, and costs associated with mucormycosis in inpatient settings in Japan.

We performed a systematic literature review, followed by a retrospective database study using hospital health claims for patients in Japan hospitalized with a diagnosis of mucormycosis between January 2010 and January 2019. Outcomes assessed included duration of index hospitalization; index stay mortality; hospital readmission within 30, 60, and 90 days after index hospitalization discharge; drug/treatment utilization and patterns; number of patients examined for mucormycosis during the index hospitalization; and index stay inpatient costs.

From https://www.selleckchem.com/products/CI-1040-(PD184352).html of articles describing 133 patients with mucormycosis, mortality in the index hospitalization was 55.6%. From our database study of 126 patients hospitalized for mucormycosis, mortality during the index hospitalization was 35.7% and mean index stay duration was 94 days. Hematologic malignancies were the most common risk factor in the literature review and the most common comorbidity in the database study. During the index stay, 39 patients (31.0%) received liposomal amphotericin B (L-AMB) treatment and 74 patients (58.7%) received other antifungal treatments. Median total inpatient costs for the index hospitalization were equivalent to approximately US$60,945, including US$29,283 in drug costs.

This study investigated the healthcare resource utilization and cost of medical resources caused by mucormycosis in Japan. The drug costs for antifungal treatments comprised about half of total inpatient costs. Mucormycosis leads to high mortality, high healthcare resource utilization, and high costs.
This study investigated the healthcare resource utilization and cost of medical resources caused by mucormycosis in Japan. The drug costs for antifungal treatments comprised about half of total inpatient costs. Mucormycosis leads to high mortality, high healthcare resource utilization, and high costs.Edmund T. Whittaker's second edition of his A History of the Theories of Aether and Electricity is famous for his treatment of Einstein as an almost irrelevant character in the emergence of what he called "the relativity theory of Poincaré and Lorentz." Historians of science have given a number of explanations, which include Whittaker's scientific conservatism as an old classical physicist, his commitment to the ether, the pre-eminent role he attributed to mathematics over physics, and foundational philosophical disagreements, to name a few. And in the background, often more implicit than forthright, the accusation of antisemitism looms over Whittaker. In this paper I intend to shed new light on this controversy by taking into consideration the abundant correspondence between Whittaker and his son preserved in the archives of the Fisher Library, University of Toronto. With it, we will get a more complex and personal view of the context in which his attempt at dethroning Einstein took place. Together with the abovementioned reasons, this correspondence shows that the problematic status quo of general relativity in the early 1950s, a period that has been described as the low-mark of general relativity, was very influential in the historical treatment he gave to Einstein. This is an aspect hardly mentioned in the historical work on this controversy and, from this correspondence, it appears to be central to understanding Whittaker at the time of drafting the new History. His possible antisemitic bias will also be addressed, though with the insufficient information on this subject the matter cannot be settled.
To investigate alterations in deep retinal vascular complex (DVC) in patients with non-neovascular intermediate AMD (iAMD), treatment-naïve quiescent macular neovascularization (qMNV), exudative AMD (eAMD) by means of OCT angiography (OCTA).

Patients with iAMD, qMNV, eAMD and healthy controls presenting in the Department of Ophthalmology of the Centre Hospitalier Intercommunal de Créteil between January 2016 and January 2018, were retrospectively included. 3 × 3-mm OCTA (AngioVue RTVue XR Avanti) perfusion density (PD) of DVC was computed in all groups at baseline and follow up (12.0 ± 1.1 months).

A total of 46 eyes of 45 patients were enrolled 11/46 iAMD, 10/46 qMNV, 13/46 eAMD, 12/46 control eyes. PD showed a significant decrease during follow-up in qMNV (
 = 0.0059) and iAMD (
 = 0.0076) eyes. PD in eAMD and healthy controls didn't show significant changes.

PD decreases at the level of DVC in eyes with qMNV and iAMD, while in eAMD eyes, PD is stable throughout follow up, suggesting that repeated anti-vascular endothelial growth factor (VEGF) injections do not impact on the DVC PD.
PD decreases at the level of DVC in eyes with qMNV and iAMD, while in eAMD eyes, PD is stable throughout follow up, suggesting that repeated anti-vascular endothelial growth factor (VEGF) injections do not impact on the DVC PD.Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. The aim of the present study was to investigate the effects of herniarin on genotoxicity and apoptosis induced by cisplatin in rat bone marrow cells. The experimental rats were treated with four different doses of herniarin (50, 100, 200, and 400 mg/kg.) for seven consecutive days. The cisplatin (5 mg/kg, i.p.) was injected into mice 1 h after the last oral herniarin administration on the seventh day. #link# The protective effects of herniarin were investigated by hematological test, flow cytometry, micronucleus assay, and reactive oxygen species (ROS) level analysis. Herniarin caused a marked reduction in the frequencies of micronucleated polychromatic erythrocytes (MnPCEs) and micronucleated normochromatic erythrocytes (MnNCEs) 24 h after exposure to cisplatin at doses of 200 and 400 mg/kg. Furthermore, herniarin significantly increased the levels of both red and white blood cells in peripheral blood. Treatment of rats with herniarin before cisplatin, significantly decreased the percentage of apoptotic and necrotic cells and the ROS level in bone marrow cells.

11/14/2024

Another hate hoax from Jews at soccer match in Amsterdam

https://newstarget.com/2024-11-13-jews-antisemitic-violence-soccer-match-provoked-muslims.html

Last week, violence at a soccer match in Amsterdam between fans of the Dutch team Ajax and the Israeli team Maccabi Tel Aviv inspired dozens of headlines about “antisemitic squads” attacking supporters just because they’re Jewish. However, like many of the peace protests at college campuses in the U.S. several months ago, the mainstream media […]

www.newstarget.com

11/13/2024

Another hate hoax from Jews at soccer match in Amsterdam

https://www.naturalnews.com/2024-11-13-jews-antisemitic-violence-soccer-match-provoked-muslims.html

Last week, violence at a soccer match in Amsterdam between fans of the Dutch team Ajax and the Israeli team Maccabi Tel Aviv inspired dozens of headlines about “antisemitic squads” attacking supporters just because they’re Jewish. However, like many of the peace protests at college campuses in the U.S. several months ago, the mainstream media […]

www.naturalnews.com

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12/19/2023

Freedom of Speech has seemed like a long distance dream in American culture as of the last decade. However, Billionaire Elon Musk has decided enough is enough and filed a defamation lawsuit against the liberal leaning watchdog Media Matters for America. On this episode of 360 View, Scottie Nell Hughes speaks to her panel (Lionel, Legal and Media Analyst; Oli London, Social Media Commentator; Steve Malzberg, Media Commentator) about how the lawsuit against Media Matters is playing out in a Texas courtroom and what will be the effects for freedom of speech and social media platforms around the world?

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12/19/2023

Freedom of Speech has seemed like a long distance dream in American culture as of the last decade. However, Billionaire Elon Musk has decided enough is enough and filed a defamation lawsuit against the liberal leaning watchdog Media Matters for America. On this episode of 360 View, Scottie Nell Hughes speaks to her panel (Lionel, Legal and Media Analyst; Oli London, Social Media Commentator; Steve Malzberg, Media Commentator) about how the lawsuit against Media Matters is playing out in a Texas courtroom and what will be the effects for freedom of speech and social media platforms around the world?

Posts

12/09/2024


Revision surgeries were not required in the primary group. In the secondary group, there was 1 revision due to deep infection, and 3 other patients required dorsal plate removal. Excluding plate removal, the Kaplan-Meier survival at 3 years was not significantly different between groups (
= .775).

Although arthrodesis of the first MTP joint was an effective procedure for hallux rigidus, the clinical outcomes in patients who had prior hallux valgus surgery were worse than those for patients who underwent primary surgery for hallux rigidus.

Level III, retrospective cohort study.
Level III, retrospective cohort study.
To evaluate outcomes, healthcare resource utilization, and costs associated with mucormycosis in inpatient settings in Japan.

We performed a systematic literature review, followed by a retrospective database study using hospital health claims for patients in Japan hospitalized with a diagnosis of mucormycosis between January 2010 and January 2019. Outcomes assessed included duration of index hospitalization; index stay mortality; hospital readmission within 30, 60, and 90 days after index hospitalization discharge; drug/treatment utilization and patterns; number of patients examined for mucormycosis during the index hospitalization; and index stay inpatient costs.

From https://www.selleckchem.com/products/CI-1040-(PD184352).html of articles describing 133 patients with mucormycosis, mortality in the index hospitalization was 55.6%. From our database study of 126 patients hospitalized for mucormycosis, mortality during the index hospitalization was 35.7% and mean index stay duration was 94 days. Hematologic malignancies were the most common risk factor in the literature review and the most common comorbidity in the database study. During the index stay, 39 patients (31.0%) received liposomal amphotericin B (L-AMB) treatment and 74 patients (58.7%) received other antifungal treatments. Median total inpatient costs for the index hospitalization were equivalent to approximately US$60,945, including US$29,283 in drug costs.

This study investigated the healthcare resource utilization and cost of medical resources caused by mucormycosis in Japan. The drug costs for antifungal treatments comprised about half of total inpatient costs. Mucormycosis leads to high mortality, high healthcare resource utilization, and high costs.
This study investigated the healthcare resource utilization and cost of medical resources caused by mucormycosis in Japan. The drug costs for antifungal treatments comprised about half of total inpatient costs. Mucormycosis leads to high mortality, high healthcare resource utilization, and high costs.Edmund T. Whittaker's second edition of his A History of the Theories of Aether and Electricity is famous for his treatment of Einstein as an almost irrelevant character in the emergence of what he called "the relativity theory of Poincaré and Lorentz." Historians of science have given a number of explanations, which include Whittaker's scientific conservatism as an old classical physicist, his commitment to the ether, the pre-eminent role he attributed to mathematics over physics, and foundational philosophical disagreements, to name a few. And in the background, often more implicit than forthright, the accusation of antisemitism looms over Whittaker. In this paper I intend to shed new light on this controversy by taking into consideration the abundant correspondence between Whittaker and his son preserved in the archives of the Fisher Library, University of Toronto. With it, we will get a more complex and personal view of the context in which his attempt at dethroning Einstein took place. Together with the abovementioned reasons, this correspondence shows that the problematic status quo of general relativity in the early 1950s, a period that has been described as the low-mark of general relativity, was very influential in the historical treatment he gave to Einstein. This is an aspect hardly mentioned in the historical work on this controversy and, from this correspondence, it appears to be central to understanding Whittaker at the time of drafting the new History. His possible antisemitic bias will also be addressed, though with the insufficient information on this subject the matter cannot be settled.
To investigate alterations in deep retinal vascular complex (DVC) in patients with non-neovascular intermediate AMD (iAMD), treatment-naïve quiescent macular neovascularization (qMNV), exudative AMD (eAMD) by means of OCT angiography (OCTA).

Patients with iAMD, qMNV, eAMD and healthy controls presenting in the Department of Ophthalmology of the Centre Hospitalier Intercommunal de Créteil between January 2016 and January 2018, were retrospectively included. 3 × 3-mm OCTA (AngioVue RTVue XR Avanti) perfusion density (PD) of DVC was computed in all groups at baseline and follow up (12.0 ± 1.1 months).

A total of 46 eyes of 45 patients were enrolled 11/46 iAMD, 10/46 qMNV, 13/46 eAMD, 12/46 control eyes. PD showed a significant decrease during follow-up in qMNV (
 = 0.0059) and iAMD (
 = 0.0076) eyes. PD in eAMD and healthy controls didn't show significant changes.

PD decreases at the level of DVC in eyes with qMNV and iAMD, while in eAMD eyes, PD is stable throughout follow up, suggesting that repeated anti-vascular endothelial growth factor (VEGF) injections do not impact on the DVC PD.
PD decreases at the level of DVC in eyes with qMNV and iAMD, while in eAMD eyes, PD is stable throughout follow up, suggesting that repeated anti-vascular endothelial growth factor (VEGF) injections do not impact on the DVC PD.Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. The aim of the present study was to investigate the effects of herniarin on genotoxicity and apoptosis induced by cisplatin in rat bone marrow cells. The experimental rats were treated with four different doses of herniarin (50, 100, 200, and 400 mg/kg.) for seven consecutive days. The cisplatin (5 mg/kg, i.p.) was injected into mice 1 h after the last oral herniarin administration on the seventh day. #link# The protective effects of herniarin were investigated by hematological test, flow cytometry, micronucleus assay, and reactive oxygen species (ROS) level analysis. Herniarin caused a marked reduction in the frequencies of micronucleated polychromatic erythrocytes (MnPCEs) and micronucleated normochromatic erythrocytes (MnNCEs) 24 h after exposure to cisplatin at doses of 200 and 400 mg/kg. Furthermore, herniarin significantly increased the levels of both red and white blood cells in peripheral blood. Treatment of rats with herniarin before cisplatin, significantly decreased the percentage of apoptotic and necrotic cells and the ROS level in bone marrow cells.

11/14/2024

Another hate hoax from Jews at soccer match in Amsterdam

https://newstarget.com/2024-11-13-jews-antisemitic-violence-soccer-match-provoked-muslims.html

Last week, violence at a soccer match in Amsterdam between fans of the Dutch team Ajax and the Israeli team Maccabi Tel Aviv inspired dozens of headlines about “antisemitic squads” attacking supporters just because they’re Jewish. However, like many of the peace protests at college campuses in the U.S. several months ago, the mainstream media […]

www.newstarget.com

11/13/2024

Another hate hoax from Jews at soccer match in Amsterdam

https://www.naturalnews.com/2024-11-13-jews-antisemitic-violence-soccer-match-provoked-muslims.html

Last week, violence at a soccer match in Amsterdam between fans of the Dutch team Ajax and the Israeli team Maccabi Tel Aviv inspired dozens of headlines about “antisemitic squads” attacking supporters just because they’re Jewish. However, like many of the peace protests at college campuses in the U.S. several months ago, the mainstream media […]

www.naturalnews.com

09/20/2024


Buy NBA workforce hats from the official online retailer of the NBA. Followers can take a look at all the shows in the NBA podcast slate together with staff reveals, Right here. It’s the same pole, Damian Lillard assures because in spite of everything these years he can still see the nails in its facet, all curled and gnarled. 10. Jason Richardson - Whereas he shouldn't be the same participant he as soon as was in Golden State, J-Rich can still shoot the 3 and provide scoring to groups looking for a shooting guard. 6. Tayshaun Prince - Prince might have develop into a forgotten man with the Piston's struggles over the previous couple of years, but the athletic lefty can still guard the opponent's best player while offering his traditional slashing/exterior shooting skills. 19. Grant Hill - The all of the sudden durable forward confirmed that he can still present a steady presence as he did for Phoenix last yr. CP3 appeared to him typically as West can shoot from anywhere on the ground and can make a stable addition to any staff. Who would you need commanding the ground as your place to begin guard? These three athletes had been all great NBA players who're at the moment retired. This was the fourth year in a row the Warriors, now nicely on their way to establishing considered one of the nice basketball dynasties, performed the Cavaliers in the NBA finals.

He was a tremendous asset for the Houston Rockets last 12 months and at all times seems to be in the appropriate place at the appropriate time. We're looking at the newest odds for the 2024 NBA Defensive Participant of the 12 months Award, with Rudy Gobert closing as the runaway favourite followed by rookie Victor Wembanyama. AJC tweeted in response to the NBA’s statement “While we're glad the NBA Commissioner shall be assembly with Kyrie subsequent week to debate his actions, Kyrie's latest comments present that, for him, every week is too lengthy at this point. AJC CEO Ted Deutch added, “After his non-apology yesterday, Kyrie had the possibility to clear the air with a easy sure or no query: “do you could have any antisemitic beliefs? Nets owner Joe Tsai initially tweeted: “I’m disenchanted that Kyrie seems to assist a movie primarily based on a e book stuffed with antisemitic disinformation. Nevertheless, just hours after the announcement of the suspension, Irving posted a message on his Instagram account, the place he conceded that the movie "contained some false anti-Semitic statements, narratives, and languages that had been untrue and offensive to the Jewish Race/Religion." Whereas he went on to directly apologize to "All Jewish households and Communities which might be damage and affected from my post," he indicated that there have been components of the documentary movie with which he still agrees.

Chicago had double the offensive rebounds because the Hawks. 7. Carl Landry - The former Purdue Boilermaker has labored his approach into becoming a stable low post presence for NBA groups looking so as to add some offensive punch. He is likely wanting to hitch a championship contender and the Chicago Bulls come to mind as a possible suitor to pair with Derrick Rose within the backcourt. While they didn't make any headway within the playoffs, the Spurs were a perennial contender during the years of Gervin. Brown has actually developed his game over the previous couple of years and should discover groups prepared to present him that chance. 17. Shannon Brown - The former Proviso East star and Michigan State Spartan has never been known for his lack of potential. 13. Kris Humphries - Identified extra for his failed marriage with Kim Kardashian than his basketball expertise, the former University of Minnesota product was a double-double machine down the stretch for brand spanking new Jersey final season. 20. Chase Budinger - The previous volleyball star really got here into his own final season with the Houston Rockets.

Houston Rockets vs. Miami Heat Predictions, Picks, Odds World Sports activities Network . 15. Samuel Dalembert - Dalembert has already been linked to joining the Miami Heat as they can use a prolonged center to control the glass and block shots. “I assume the group is trying to take that stance the place we will talk via this. “I hate it.” https://telegra.ph/Think-of-A-New-York-Knicks-Now-Draw-A-New-York-Knicks-I-Wager-You-will-Make-The-same-Mistake-As-Most-people-Do-09-20 “Cowardly,” some more people echoed. Learn extra concerning the antisemitic trope of Holocaust denial in AJC’s Translate Hate glossary of antisemitic terms. Furthermore, concerning the book’s labeling of the Holocaust as one of the five main falsehoods, denying the systematic destruction and genocide of the Jewish individuals or denying the scope of the brutalities committed by the Nazis and their collaborators in the course of the Holocaust is antisemitic. Simply hours after Irving’s Thursday refusal to answer whether or not he had any antisemitic beliefs, the Brooklyn Nets suspended their star player for no less than 5 games. On Thursday, Nov. 3, the Brooklyn Nets suspended their star guard Kyrie Irving for refusing to apologize for peddling a movie full of harmful antisemitic tropes to his 4.6 million Twitter followers. How did the NBA and the Nets Respond to Irving? Within the video, Jones claims secret societies or “occults” are in control of America, which Irving stated he believes to be true.

Between the NFL, NBA, MLB, NHL and MLS, there are 147 professional sports teams situated in North America, and that quantity is prone to rise over the following few years. Here’s a breakdown of what we all know happened, why it’s harmful, and the way the NBA, the Nets, and Irving responded. Tennis equipment (nets, rackets, apparel), books and tennis posters featuring stars like Maria Sharapova, Anna Kournikova, Andy Roddick, Rafael Nadal, Reger Federer, Serena Williams, Marat Safin, Nicole Vaidisova, Ashley Harkleroad, Daniela Hantuchova, Andre Agassi, Bjorn Borg, Boris Becker, and Pete Sampras, among others, and tennis books. In what appeared to be the ultimate straw for the Nets, during an interview Irving refused to apologize for his action nor did he denounce the film. The movie purports to uncover the biblical identity of Black individuals, or true identification of the Kids of Israel, which Islam, Judaism, and Christianity have allegedly covered up for centuries. Meanwhile, the guide and movie spotlighted by Irving echoed a long-standing antisemitic trope widespread amongst Black supremacists that claims “white” Jews are “not the real Jews.” As an alternative, these Black supremacists allege without proof that Jews are imposters who have stolen the identity and “birthright” of Black individuals as the true chosen folks of God.

09/14/2024


However, additional data are needed to test the stability of the PSCD. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
Studies use different instruments to measure cognitirating cognitive tests permit direct comparisons of individuals across studies and pooling data for joint analyses.

We began our legacy item bank with data from the Adult Changes in Thought study (
= 5,546), the Alzheimer's Disease Neuroimaging Initiative (
= 3,016), the Rush Memory and Aging Project (
= 2,163), and the Religious on such as the Mini-Mental State Examination, the Alzheimer's Disease Assessment Scale-Cognitive Subscale, the Wechsler Memory Scale, and the Boston Naming Test. CocalibOrders Study (
= 1,456). Our workflow begins with categorizing items administered in each study as indicators of memory, executive functioning, language, visuospatial functioning, or none of these domains. We use confirmatory factor analysis models with data from the most recent visit on the pooled sample across these four studies for cocalibration and derive item parameters for all items. Using these item parameters, we then estimate factor scores along n of cognition in the context of aging and dementia. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
We have implemented a large-scale effort to harmonize and cocalibrate cognitive domain scores across multiple studies of cognitive aging. Scores on the same metric facilitate meta-analyses of cognitive outcomes across studies or the joint analysis of individual data across studies. Our systematic approach allows for cocalibration of additional studies as they become available and our growing item bank enables robust investigation of cognition in the context of aging and dementia. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
Debate continues regarding the use of self- versus informant-report to diagnose mild cognitive impairment (MCI) with studies reporting patients both overestimating and underestimating their abilities relative to informants. We assessed concordance of self- versus informant-report of cognitive decline with objective cognitive and functional performance in the participants of the preventing Alzheimer's dementia with cognitive remediation plus transcranial direct current stimulation in mild cognitive impairment and depression randomized controlled trial (PACt-MD).

Three hundred six participants with MCI, and their informants, reported on cognitive decline; the participants also completed a comprehensive assessment of objective cognitive and functional performance. Based on the discrepancy between self- versus informant-report of cognitive decline, we grouped participants into categories of underestimators, congruent estimators, and overestimators.

Informant- but not self-reported cognitive decline significand cognitive performance in patients with MCI. Our findings highlight clinical and research value in the assessment and consideration of degree of discrepancy between self- and informant-reports of cognitive decline in MCI. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
The present study investigated cognitive mechanisms underlying the ability to stop "autocorrect" errors elicited by unexpected words in a read-aloud task, and the utility of autocorrection for predicting Alzheimer's disease (AD) biomarkers.

Cognitively normal participants (total
= 85;
= 64 with cerebrospinal fluid [CSF] biomarkers) read aloud six short paragraphs in which 10 critical target words were replaced with autocorrect targets, for example,
. Autocorrect targets either replaced the most expected/
completion (i.e.,
) or a less expected/
completion (i.e.,
), and within each paragraph half of the autocorrect targets were content words (e.g.,
) and half were function words (e.g.,
). Participants were instructed to avoid autocorrecting.

Participants produced more autocorrect errors in paragraphs with dominant than with nondominant targets, and with function than with content targets. Cognitively normal participants with high CSF Tau/Aβ42 (i.e., an AD-like biomarker profile) produc implicates monitoring and attention (rather than semantic processing) in the earliest of cognitive changes associated with AD risk. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
The present study aims to explore the relative effectiveness of two group-based cognitive rehabilitation programs for reducing fatigue in pediatric acquired brain injury (pABI).

This is an exploratory study of secondary endpoints in a blinded, parallel-randomized controlled trial with children and adolescents (ages 10-17 years) with pABI and reported executive dysfunction. It investigates the effectiveness of a metacognitive program (pediatric goal management training,
= 36) compared to a psychoeducational program (pediatric brain health workshop,
= 37) for reducing fatigue (Pediatric Quality of Life Inventory, Multidimensional Fatigue Scale), 8 weeks and 6 months postintervention.

Seventy-three participants completed the allocated interventions, and 71 attended the 6-month follow-up. The results showed a significant decrease in parent-reported fatigue for both interventions from baseline to the 6-month follow-up. Forty percent of the total sample had a reliable change. There was no significant diue improvement. Developmental factors are important to consider when tailoring pediatric interventions, as well as modifiable factors associated with fatigue. (PsycInfo Database Record (c) 2022 APA, all rights reserved).On May 14, 2022, a gunman walked into a supermarket in Buffalo, NY, and opened fire on the customers, killing 10 and injuring three. The alleged killer published a document explaining he chose a supermarket in a predominantly Black neighborhood to maximize the likelihood of killing Black people. He believed in the "Great Replacement" theory that Jews were conspiring to commit "White Genocide" by having inferior races outbreed the superior White race. The 180-page "Manifesto" relied on a mix of Internet memes, plagiarized arguments from a similar killing in New Zealand, links to White nationalist and antisemitic websites, and citations to scientific publications. Overwhelmingly, the scientific publications cited in the document were from psychology. In this brief article, the author contends that psychologists need to ask themselves why an alleged deranged killer took his inspiration from psychology and not, for example, human genetics. The answer is that geneticists have recognized the responsibility that comes along with inquiry. While researchers are free to pursue any questions they desire, scientific and editorial standards still need to be met for disciplinary integrity. The heart of academic freedom is the ability and responsibility to distinguish responsible scholarship from its pretender. Psychology must do better. (PsycInfo Database Record (c) 2022 APA, all rights reserved).Cheiron's Book Prize Committee is pleased to announce that the recipient of the 2022 Prize is Nadine Weidman, Lecturer on the History of Science at Harvard University, for her book Killer Instinct The Popular Science of Human Nature in Twentieth-Century America. In other news from the Society for the History of Psychology, Marjorie Lorch has recently published an article on how the concept of a matched control group was initially developed in neuropsychological testing. Lorch, M. https://www.selleckchem.com/products/ch6953755.html P. (2022). Defining 'normal' Methodological issues in Aphasia and intelligence research. Cortex, 153, 224-234. (PsycInfo Database Record (c) 2022 APA, all rights reserved).Understanding the longitudinal dynamics of behavior, their stability and change over time, are of great interest in the social and behavioral sciences. Researchers investigate the degree to which an observed measure reflects stable components of the construct, situational fluctuations, method effects, or just random measurement error. An important question in such models is whether autoregressive effects occur between the residuals, as in the trait-state occasion model (TSO model), or between the state variables, as in the latent state-trait model with autoregression (LST-AR model). In this article, we compare the two approaches by applying revised latent state-trait theory (LST-R theory). Similarly to Eid et al. (2017) regarding the TSO model, we show how to formulate the LST-AR model using definitions from LST-R theory, and we discuss the practical implications. We demonstrate that the two models are equivalent when the trait loadings are allowed to vary over time. This is also true for bivariate model versions. The different but same approaches to modeling latent states and traits with autoregressive effects are illustrated with a longitudinal study of cancer-related fatigue in Hodgkin lymphoma patients. (PsycInfo Database Record (c) 2022 APA, all rights reserved).Next Eigenvalue Sufficiency Test (NEST; Achim, 2017) is a recently proposed method to determine the number of factors in exploratory factor analysis (EFA). NEST sequentially tests the null-hypothesis that k factors are sufficient to model correlations among observed variables. Another recent approach to detect factors is exploratory graph analysis (EGA; Golino & Epskamp, 2017), which rules the number of factors equal to the number of nonoverlapping communities in a graphical network model of observed correlations. We applied NEST and EGA to data sets under simulated factor models with known numbers of factors and scored their accuracy in retrieving this number. Specifically, we aimed to investigate the effects of cross-loadings on the performance of NEST and EGA. In the first study, we show that NEST and EGA performed less accurately in the presence of cross-loadings on two factors compared with factor models without cross-loadings We observed that EGA was more sensitive to cross-loadings than NEST. In the second study, we compared NEST and EGA under simulated circumplex models in which variables showed cross-loadings on two factors. Study 2 magnified the differences between NEST and EGA in that NEST was generally able to detect factors in circumplex models while EGA preferred solutions that did not match the factors in circumplex models. In total, our studies indicate that the assumed correspondence between factors and nonoverlapping communities does not hold in the presence of substantial cross-loadings. We conclude that NEST is more in line with the concept of factors in factor models than EGA. (PsycInfo Database Record (c) 2022 APA, all rights reserved).In recent years, psychological research has faced a credibility crisis, and open data are often regarded as an important step toward a more reproducible psychological science. However, privacy concerns are among the main reasons that prevent data sharing. Synthetic data procedures, which are based on the multiple imputation (MI) approach to missing data, can be used to replace sensitive data with simulated values, which can be analyzed in place of the original data. One crucial requirement of this approach is that the synthesis model is correctly specified. In this article, we investigated the statistical properties of synthetic data with a particular emphasis on the reproducibility of statistical results. To this end, we compared conventional approaches to synthetic data based on MI with a data-augmented approach (DA-MI) that attempts to combine the advantages of masking methods and synthetic data, thus making the procedure more robust to misspecification. In multiple simulation studies, we found that the good properties of the MI approach strongly depend on the correct specification of the synthesis model, whereas the DA-MI approach can provide useful results even under various types of misspecification.