It has the potential to send users down a “K hole,” otherwise known as a bad trip, and can induce psychosis. Research in animals and recreational users has shown chronic use of the drug impairs both short- and long-term cognition.

Matthew Perry’s death raised alarms when the initial toxicology screening attributed his death to the acute effects of ketamine.

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https://childrenshealthdefense.org/defender/soaring-market-ketamine-doctors-patients-kff/?utm_source=sovren&utm_medium=social&utm_campaign=defender&utm_id=20240202

Between 500-750 ketamine clinics have cropped up across the U.S., as off-label use of ketamine hydrochloride for depression and anxiety gains in popularity. But one analyst likened doctors’ use of the drug, implicated in the death of actor Matthew Perry, to a “Wild West” scenario.

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