PPI use was associated with a 34% overall increase in infections requiring hospitalization. Bacterial infections were 56% higher and viral infections increased by 30% in the PPI group.

Infection rates rose by 52% for digestive tract infections, 47% for infections of the ear, nose or throat, 31% for the nervous system, 22% for the lower respiratory tract and 20% for the urinary tract or kidneys.

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https://childrenshealthdefense.org/defender/nexium-indigestion-babies-serious-infections/?utm_source=sovren&utm_medium=social&utm_campaign=defender&utm_id=20230828

Proton pump inhibitors (PPIs) relieve heartburn in adults, but they’re also prescribed to children. A French study reported in JAMA Pediatrics found young children on PPIs had higher rates of bacterial, viral, respiratory and other infections.

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