This review will greatly benefit anyone practicing assisted reproduction and clinical embryology.Medical practice has undergone a massive drift over the past several years. With the advent of modernization and technical advancements in both diagnostic and therapeutic fields, bedside clinical skills have suffered a setback. Increasing patient load in the hospitals, administrative commitments of the physicians, and need to get superspecialty fellowships are some of the factors which preclude resident teaching, which, in-turn hamper their long-term clinical skills and influence the patient-doctor relationship. https://www.selleckchem.com/products/canagliflozin.html In this perspective, I narrate my own experience regarding changing attitude of the younger generation of doctors toward patient care and also describe the role of a mentor in shaping the believes and practices of his medical students. Using real-world examples, I further discuss the obstacles which hamper good medical practice and suggest possible ways to overcome some of them.India has confronted the COVID-19 pandemic in 2020, in the form of first wave and again in first half of 2021 in the form of second wave. To combat the persistent transmission of the coronavirus, Indian Government has started the vaccination in the country since January 2021. The immunity conferred by the vaccine can be more effective with sound immune health. In India, medicinal herbs are preferred dietary habits to enhance the immunity intrinsically. A web-based survey of herbal medicinal plants was carried out to identify the consumption trend of the medicinal herbs as an effective immune booster to reduce the spread of COVID-19. The selected herbs are ingredients of regular Indian cuisine and practiced under Ayurveda. The present study revealed that people are aware of selected medicinal herbs and consumed intentionally to boost their immunity. This type of study can be helpful in retaining the local people's knowledge on traditional medicine practices which has been vanishing.Biotechnology is a wide-ranging science that uses modern technologies to construct biological processes, organisms, cells or cellular components. The clinical new instruments, industry, and products developed by biotechnologists are useful in research, agriculture and other major fields. The biotechnology is as ancient as civilization. The food you buy, and the pets you love? Using artificial selection for crops, domesticated animals and other species, you may thank our distant ancestors for setting off the agrarian revolution. When Alexander Fleming discovered antibiotics, and when Edward Jenner invented vaccines, the biotechnology potential was harnessed. And, of course, without the mechanisms of fermentation that gave us beer, wine and cheese, it would not be possible to imagine modern society. This article summarizes some of the applications of biotechnology in food & agriculture.
Applications of biotechnology in animal and plant sector.
Applications of biotechnology in animal and plant sector.The novel coronavirus strain SARS-CoV-2 is the virus responsible for the recent global health crisis, as it causes the coronavirus disease-19 (COVID-19) in humans. Due to its high rate of spreading and significant fatality rates, the situation has escalated to a pandemic, which is the cause of immense disruption in daily life. In this study, we have taken a docking-based virtual screening approach to select natural molecules (from plants) with possible therapeutic potential. For this purpose, AUTODOCK Vina-based determination of binding affinity values (blind and active-site oriented) was obtained to short-list molecules with possible inhibitory potential against the main Mpro in SARS-CoV-2 (PDB ID 6Y2F -the monomeric form). The 4 molecules selected were Chebuloside (-8.2; -8.2), Acetoside (-8.0; -8.0), Corilagin (-8.1; -7.7) and Arjunolic Acid (-8.0; -7.6) (blind and active-site oriented docking scores (Kcal/mol) in parenthesis, respectively). Further, a comparative search, with FDA-approved drugs, has shown that Ouabain was comparable to Chebuloside with a similarity score of 0.227. This in silico finding with respect to Ouabain is significant, since this polycyclic glycoside has been shown to treat COVID-19 positive patients with a cardiovascular disease. Hydrocortisone was similar to Arjunolic acid with a score of 0.539. Again, this likeness is worthy of mention, since hydrocortisone has been used earlier for the treatment of SARS-CoV1 and MERS. However, further experimentation and validation of the results, in suitable biological model systems, are necessary to gain more insight and relevance as well as provide corroborative evidence for our in-silico findings.
The online version contains supplementary material available at 10.1007/s40011-021-01292-5.
The online version contains supplementary material available at 10.1007/s40011-021-01292-5.Sand mining is a global activity that has attracted wide attention due partly to its invaluable positive contributions to development and partly to its negative socio-environmental impacts. While sand mining supports urbanization by providing essential aggregate materials for urban real estate and construction sectors, it however undermines environmental sustainability especially in coastal regions. In spite of this, very sparse research has explained the socio-environmental dimensions of sand mining in Nigerian coastal communities. This study therefore explored the drivers and impacts of sand mining based on the data from a survey of residents in four Lagos sand mining coastal communities. Results showed that sand mining activity is driven by a number of urbanization related factors while sand mining impacts are underlined by a number of sustainability related factors. However, using exploratory analytical techniques we found that four urbanization components described the drivers of sand mining and four sustainability components described the impacts of sand mining in Lagos. The paper concludes on the puzzling dilemma of sand mining that supports thriving urbanization but undermines environmental sustainability in Lagos. The implications of the findings for environmental sustainability in Lagos coastal areas were concisely presented.
Key social traits, like queen number in eusocial insect colonies, have long been considered plastic, but the recent finding that colony social organization is under strict genetic control in multiple ant lineages challenges this view. This begs the question of which hardwired behavioral mechanism(s) generate alternative forms of social organization during colony development. We addressed this question in the Alpine silver ant,
, a species with two social forms determined by a supergene. Queens that carry exclusively the
haplotype are produced by and live in monogyne (= single-queen) colonies, whereas queens that carry at least one copy of the
haplotype are produced by and live in polygyne (= multiple-queen) colonies. With extensive field samplings and laboratory experiments, we show that both types of queens successfully establish colonies independently, without being accompanied by workers, but that they do so in contrasting ways. Monogyne queens were generally intolerant of other queens and foundeThese hardwired differences in social traits make queens carrying the
supergene haplotype more prone to cooperate and form durable associations during independent colony-founding. These findings help explain how genetic variants induce alternative forms of social organization during the ontogeny of a colony. They also illustrate how simple phenotypic differences at the individual level can result in large differences at higher levels of organization.

The online version contains supplementary material available at 10.1007/s00265-021-03105-1.
The online version contains supplementary material available at 10.1007/s00265-021-03105-1.Resilience of food systems is key to ensuring food security through crisis. The COVID-19 pandemic presents an unprecedented shock that reveals varying levels of resilience of increasingly interconnected food systems across the globe. We contribute to the ongoing debate about whether increased connectivity reduces or enhances resilience in the context of rural Pacific food systems, while examining how communities have adapted to the global shocks associated with the pandemic to ensure food security. We conducted 609 interviews across 199 coastal villages from May to October 2020 in Federated States of Micronesia, Fiji, Palau, Papua New Guinea, Solomon Islands, Tonga, and Tuvalu to understand community-level impacts and adaptations during the first 5-10 months of the COVID-19 crisis. We found that local food production practices and food sharing conferred resilience, and that imported foods could aid or inhibit resilience. Communities in countries more reliant on imports were almost twice as likely to report food insecurity compared to those least reliant. However, in places dealing with a concurrent cyclone, local food systems were impaired, and imported foods proved critical. Our findings suggest that policy in the Pacific should bolster sustainable local food production and practices. Pacific states should avoid becoming overly reliant on food imports, while having measures in place to support food security after disasters, supplementing locally produced and preserved foods with imported foods when necessary. Developing policies that promote resilient food systems can help prepare communities for future shocks, including those anticipated with climate change.The Microfinance industry has been severely affected by Covid-19. We provide detailed insights into how loan officers, the key personnel linking the lender to its borrowers, are affected in their performance and adapt their work to the pandemic. We use administrative records of an Indian Microfinance Institution and detailed panel survey data on performance, performed tasks, and work organization to document how the work environment became more challenging during the pandemic. Loan officers operate in a setting where work from home is hard to implement due to the nature of the tasks and technological constraints. The usual performance indicators appear to be mainly driven by external factors such as the nation-wide debt moratorium. Loan officers worked similar hours, but engaged less in planning activities and completed fewer of the usual tasks. Work perceptions and mental health of loan officers reflect these changes, and perceived stress was particularly high during the period of the debt moratorium.Musical meaning is often described in terms of emotions and metaphors. While many theories encapsulate one or the other, very little empirical data is available to test a possible link between the two. In this article, we examined the metaphorical and emotional contents of Western classical music using the answers of 162 participants. We calculated generalized linear mixed-effects models, correlations, and multidimensional scaling to connect emotions and metaphors. It resulted in each metaphor being associated with different specific emotions, subjective levels of entrainment, and acoustic and perceptual characteristics. How these constructs relate to one another could be based on the embodied knowledge and the perception of movement in space. For instance, metaphors that rely on movement are related to emotions associated with movement. In addition, measures in this study could also be represented by underlying dimensions such as valence and arousal. Musical writing and music education could benefit greatly from these results.