The effect of cleaner containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) for removing temporary cement remnants on dentin surface was evaluated. Flat dentin surfaces were wet-polished (Co) and HY-BOND temporary cement hard (Shofu) was applied to the surface. This temporary cement was removed using an air-scaler (Sc), brush (Br), or phosphoric acid and NaOCl (NC). A prototype cleaner containing MDP (Kuraray Noritake Dental, Tokyo, Japan) was used with agitation mode (MC+AG). KATANA Avencia block (Kuraray Noritake Dental) was luted with SA Cement Plus Automix (Kuraray Noritake Dental). Co showed significantly higher bond strength than Sc or Br (p less then 0.001 each). Bond strengths with NC (p=0.99) and MC+AG (p=0.38) did not differ significantly from that with Co. Transmission electron microscopy revealed sufficient interaction of MC+AG. Cleaner containing MDP can effectively remove temporary cement by agitation, and can be expected to improve the chemical bonding ability by binding more MDP to dentin.The aim of this review is to evaluate the long-term effectiveness of calcium silicate-based cement (CS) and calcium hydroxide (CH) for direct pulp capping (DPC) to human pulp-exposed permanent teeth. An electronic search and manual search were performed on 21 June 2019. Long-term clinical and radiographic evaluations of the effectiveness of CS and CH for DPC to human pulp-exposed teeth were included, and data extraction, risk-of-bias assessment and meta-analyses were performed. From 645 identified articles, 7 articles met the eligibility criteria. The meta-analyses comparing CS with CH and Biodentine with mineral trioxide aggregates (MTA) on DPC success rate were performed, and significant difference was observed between CS and CH (risk ratio=1.20; p=0.005), whereas no significant difference was observed between Biodentine and MTA. CS seems to be a more effective and predictable DPC material than CH; however, these analyses are based on the studies judged at high risk of bias.The objective of this study was to investigate the effects of eccentric cyclic loading on implant components using the internal joint system with titanium and zirconia abutments. Abutments were made of either pure titanium (Ti group) or zirconia (TZP group). Cyclic loading test was conducted according to the specifications of ISO 14801. https://www.selleckchem.com/products/ionomycin.html Loading condition was at 2 points assuming axial load and eccentric load. The reverse torque value reduced after the eccentric load and reduced more in the TZP group than the Ti group. Marginal gap changed after eccentric loading, and was greater in the TZP group. In the TZP group, changes in configuration were observed in the implant body, and Ti was detected on the abutment surface. From the above, the eccentric load may have worse effects than axial loads. It was suggested that the TZP group was clinically disadvantageous compared to the Ti group.This study investigated the influence of curing distance on µ-flexural strength (µ-FS) of a nano-hybrid composite, cured using the manufacturer-recommended curing time (MCT), compared to a consistent radiant exposure (CRE) using three different light-curing units (LCUs). Beams (6×2×1 mm) were cured using the MCT or CRE with a quartz-tungsten-halogen (QTH); a single-emission-peak light-emitting-diode (SLED), or a multiple-emission-peak light-emitting-diode (MLED) LCU. Specimens were cured at 0-, 2- or 8-mm distances (n=10) and the bottom irradiance and CRE were measured using a Managing Accurate Resin Curing-Resin Calibrator spectrometer. µ-FS testing was performed, and data analyzed using two-way ANOVA and Tukey multiple comparison tests (α=0.05). Mean bottom irradiance was (25.4-99.7 mW/cm2) and CRE (0.31-1.11 J/cm2). µ-FS was 422.1-516.6 MPa (MCT) and 440.4-490.4 MPa (CRE). Comparing CRE to MCT showed that µ-FS significantly decreased using the CRE at 2-mm (QTH) or the MCT at 2- and 8-mm (SLED). µ-FS may be significantly impacted by the curing protocol.This study aimed to analyze the interaction of a MDP-based universal dentin bonding system (DBS) with Er, Cr YSGG laser irradiation, measuring the microtensile bond strength to dentin over a six-month period. The experimental design involved three factors DBS (Adper Scotchbond Universal; Clearfil SE Bond, Adper Scotchbond Multipurpose and Adper Single Bond 2), laser (Control and Er, Cr YSGG), and time (initial- 7 days and 6 months). Eighty dentin samples from molars were prepared (n=10) with laser irradiation after primer and DBS application. After 7 days, were subjected to micro tensile bond strength test. The data were analyzed by three-way ANOVA and Tukey tests (p less then 0.05). Both DBS and laser significantly affected the bonding performance and their interaction was statistically significant (p=0.0194). The self-etching mode of the MDP-based universal DBS maintained the bond strength on dentin irradiated with ER, Cr YSGG after 6 months, while bonding with all other DBS deteriorated.The quality assurance (QA) of the output constancy of linear accelerators (linacs) is one of the most basic items for radiation therapy. The necessity and demand of the dosimetric audit is on the rise. We aimed at establishing an on-site dosimetric audit program with a plastic phantom in order to enrich the availability of dosimetric audit in Japan. By this, we developed and evaluated an on-site audit program in multiple institutions in 120 cases for photon and electron standard dosimetry and intensity modulated radiation therapy (IMRT) condition. For photon standard dosimetry, we evaluated the accuracies of institutional measured absorbed dose in 50 cases by this on-site audit program. For the electron standard dosimetry, we evaluated the accuracies of institutional measured absorbed dose in 25 cases. For IMRT condition, we evaluated the accuracies of the institutional calculated dose in radiation treatment planning systems in 45 cases. The agreements of the measured absorbed dose between our audit and the institutions were within±1.1% for photon standard dosimetry. The agreements of the measured absorbed dose between our audit and the institutions were within±2.1% for electron standard dosimetry. The agreements between the measured absorbed dose of our audit and the institutional calculated dose were within±2.1% for IMRT condition. We established an on-site dosimetric audit program with a plastic phantom and this program is suitable with tight criteria similar to criteria required for clinical QA.This study investigates the quality indicators (QIs) of medical care that are expected to be introduced to radiotherapy departments in Japan and evaluates whether the QIs reflect the characteristics of the treatment facilities. For this purpose, a questionnaire survey was administered to radiotherapy treatment facilities in Japan. A consensus of early QI candidates was obtained from the panel members. The characteristics identified in the candidate QIs were subdivided into 140 items covering 27 domains of medical-care contents in radiotherapy departments. These 140 items were compiled into a questionnaire, which was administered to 15 treatment facilities in Japan. The primary results indicated that 36 items in five domains are useful QI contents. The secondary findings indicated that the provision of advanced radiotherapy to several patients, the waiting time, and the radiotherapy initiated depend on the manpower of the departmental staff.Nontyphoidal Salmonella is a common cause of bacterial gastroenteritis, occasionally causing bacteremia. We herein report the case of an 80-year-old man who presented with bacteremia and pre-renal acute kidney injury (AKI) secondary to diarrhea caused by nontyphoidal Salmonella. Despite AKI improvement on fluid administration, some serological abnormalities, such as hypokalemia, hypophosphatemia, and hypouricemia, and abnormal urinary findings emerged, including renal glycosuria and aminoaciduria. Fractional excretion of phosphate and uric acid was increased, suggesting that the serological and urinary abnormalities may have arisen from Fanconi syndrome. Physicians should consider acquired Fanconi syndrome when patients with nontyphoidal Salmonella bacteremia present with electrolyte disorders.We herein report a unique form of autoimmune pancreatitis (AIP) spreading along the main pancreatic duct (MPD). A 70-year-old man was referred for a small lesion at the pancreatic neck, accompanying an adjacent cyst and dilated upstream MPD. Four years earlier, health checkup images had shown a pancreatic cyst but no mass lesion. Endoscopic ultrasonography showed a contrast-enhanced, tumorous lesion, mainly occupying the MPD. With a preoperative diagnosis of ductal neoplasms mainly spreading in the MPD, Whipple's resection was performed. The resected specimens showed MPD periductitis with IgG4-related pathology, indicating type 1 AIP. Clinicians should practice caution concerning the various AIP forms.Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBD-associated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.A 28-year-old woman was admitted during the eighth week of her pregnancy because her clinical course was consistent with rapid progressive glomerulonephritis (RPGN). Anti-glomerular basement membrane antibody (anti-GBM Ab) and myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) were positive, and the anti-GBM Ab titer being extremely high. She was treated with hemodialysis, plasma exchange and prednisolone. She survived the illness; however, neither the fetus nor her kidney function could be rescued. She had human leukocyte antigen (HLA)-DRB1*150201, which differs from the DRB1*1501 associated with anti-GBM GN. When patients have particular symptoms, we should check the urine and serum creatinine to exclude RPGN, even in cases of pregnancy.Objective This study was conducted to clarify the prevalence of short segment Barrett's esophagus (SSBE) using endoscopic observations with linked color imaging (LCI). In addition, the relationship between the presence of Barrett's epithelium (BE) and the status of H. pylori infection was investigated. Methods The study subjects were 3,353 individuals (2,186 men, 1,167 women; mean age 55.2±9.4 years old) whose status of H. pylori infection had been determined. An endoscopic observation using LCI was performed to examine the distal margin of palisade vessels and confirm the area of BE. The prevalence of BE ≥5 mm in length was investigated. Results BE was diagnosed in 1,884 (56.2%) subjects, with lengths of less then 10, 10-19, 20-29, and ≥30 mm found in 1,005, 851, 27, and 1, respectively. Its prevalence in H. pylori-negative, H. pylori-positive, and post-eradicated subjects was 41.7%, 64.4%, and 69.9%, respectively (p less then 0.001). The duration since successful eradication of H. pylori did not affect the prevalence of BE.