are centre. Early case detection and timely referral may provide an opportunity to avoid surgical interventions.
To generate epidemiological data of rotavirus diarrhea among hospitalized children less than 5 y of age and to characterize the circulating rotavirus genotypes post introduction of rotavirus vaccine in Universal Immunization Program (UIP).

This prospective study was conducted from April 2016 to July 2019 at Sardar Vallabhbhai Patel Post Graduate Institute of Paediatrics & SCB Medical College, Cuttack, Odisha among hospitalized children with acute gastroenteritis (AGE) under five years of age. Stool samples collected were tested for rotavirus by a commercial enzyme immunoassay and strains were characterized by reverse-transcription polymerase chain reaction (PCR). The data was analysed using a chi-square test with 95% confidence interval and risk ratio.

Rotavirus diarrhea was seen in 715 (36.4%) of the 1963 samples tested.The peak incidence of rotavirus diarrhea was during the winter season, i.e., from the month of December to February. Most of the infections were in children between 6 mo to 2 y of age, affecting boys and girls equally. The commonest genotypes were G3P[8] (50.34%) followed by G1P[8] (17.46%).

This study highlights the high prevalence of rotavirus diarrhea among children which emphasize the need for continued rotavirus vaccination. The changing patterns of genotype distribution stress the need for continued surveillance post introduction of vaccines to understand the effect of vaccines on strain evolution over a longer period and detect emergence of new genotypes.
This study highlights the high prevalence of rotavirus diarrhea among children which emphasize the need for continued rotavirus vaccination. The changing patterns of genotype distribution stress the need for continued surveillance post introduction of vaccines to understand the effect of vaccines on strain evolution over a longer period and detect emergence of new genotypes.Prostaglandin E synthase (PGES) catalyzes the conversion of prostaglandin H2 to prostaglandin E2 in the presence of glutathione (GSH) in mammals. Amid the limited knowledge on prostaglandin and its related enzymes in insects, we recently identified PGES from the silkworm Bombyx mori (bmPGES) and determined its crystal structure complexed with GSH. In the current study, we investigated the substrate-binding site of bmPGES by site-directed mutagenesis and X-ray crystallography. We found that the residues Tyr107, Val155, Met159, and Glu203 are located in the catalytic pockets of bmPGES, and mutagenesis of each residue reduced the bmPGES activity. Our results suggest that these four residues contribute to the catalytic activity of bmPGES. Overall, this structure-function study holds implications in controlling pests by designing rational and efficient pesticides.Israeli-Palestinian adolescents living in Israel may have a unique set of stressors, given the societal tension between Israeli and Palestinian practices that may influence youths' identities (e.g., modernization, gender roles). However, little research has examined risk factors that may undermine one's ability to cope with stress effectively within this population. Thus, the current study examined the role of religiosity, self-control skills and emotional attachment style as risk factors for less effective (more passive, fewer active strategies) coping with stressful situations. Participants (n  = 487) were recruited from seven junior high schools located in the Northern Triangle region of Israel. Consistent with hypotheses, poorer self-control skills, and anxious and avoidant emotional attachment style were each associated with a greater likelihood to engage in passive coping skills. In addition to positive correlation between religiosity and active coping skills in response to stressful situations, these findings parallel prior studies that have examined broader demographic samples, suggesting the cross-cultural relevance of these risk factors for effective coping with stress.This study aimed at determining the publication trend in Islamic medical ethics; finally, a road map was designed. All published English and Persian papers in Islamic medical ethics were searched until June 2017. Finally, 971 English papers and 204 Persian papers were analyzed. Our results show that publication in Islamic medical ethics started in 1973. The beginning of life was considered the most favorable subject followed by public health and biotechnology by both Iranian and non-Iranian scholars. Taken together, the publication trend in Islamic medical ethics has experienced ups and downs and is not as satisfactory as it should be.Though faith community nurses (FCNs) serve many roles in churches and communities, little is known about their roles or effectiveness in public health interventions. This systematic review summarizes the literature on recent faith community nursing interventions, examining trends, evaluating rigor, and proposing future research directions. Articles were downloaded from PubMed and CINAHL, and 24 studies were included. Interventions addressed various health outcomes. The FCNs participated in research by recruiting participants, developing study measures, and implementing programs. Results reported mainly process evaluation and provided few outcomes. Better evaluation is needed to understand the effectiveness of FCNs in public health research.Since December 2019, the COVID-19 pandemic has caused serious mental health challenges and consequently the Turkish population has been adversely affected by the virus. The present study examined how meaning in life related to loneliness and the degree to which religious coping strategies mediated these relations. Participants were a sample of 872 adults (242 males and 360 females) drawn from general public in Turkey. Data were collected using Meaning in Life Questionnaire, UCLA Loneliness Scale, and the Religious Coping Measure. Meaning in life was associated with more positive religious coping and less negative religious coping and loneliness. Positive religious coping was associated with less loneliness, while negative religious coping was associated with more loneliness. Religious coping strategies mediated the impact of meaning in life on loneliness. These findings suggest that greater meaning in life may link with lesser loneliness due to, in part, an increased level of positive religious coping strategies and a decreased level of negative coping strategies.This study examines differences in experiences between Muslim and Christian Arabs (N = 1016) utilizing data from the Detroit Arab American Study (DAAS). Results showed that Muslim and Christian Arabs held similar levels of religious centrality and psychological distress but differed in reports of negative religious public regard and experiences of discrimination. Additionally, religious public regard and religious centrality predicted psychological distress similarly for Muslim and Christian Arab Americans. The relationship between religious centrality and psychological distress was mediated by negative religious public regard and perceived discrimination. Study implications are discussed.An overlooked reason to study atheism and health is that it provides a reasonably strong test of the broader religion-health relationship. Using data from the 2011/2012 Canadian Community Health Survey (n > 8000) I explored the health differences between atheists and eight categories of religious identities (nonreligious, Anglican, Baptist, Christian, Protestant, Catholic, United Church, and All Others). Surprisingly, results showed no substantive differences between atheists and non-atheists for self-rated health, emotional well-being, and psychological well-being. In contrast, results showed substantive and consistent differences between atheists and non-atheists with respect to social well-being. Results appear to suggest that while religious groups report superior scores on health proxies relative to atheists, this does not translate into substantive health differences.This study explored homeless people's (N = 164) spiritual well-being (SWB) in relation to race, mental illness, physical disease, resilience, and trait mindfulness. The results of hierarchical regression analysis revealed that variables of race (p = 0.003), mental illness (p = 0.04), resilience (p  less then  0.001) and trait mindfulness (p  less then  0.001) contributed to participants' SWB. These findings were critical to research related to homelessness and service provisions in finding that homeless people with certain backgrounds (e.g., mental illness) might have lower SWB than their counterparts. This research also revealed protective factors (e.g., resilience) that could help promote SWB.
To evaluate the overall prevalence of obstructive sleep apnea (OSA) in interstitial lung disease (ILD).

We performed a systematic search of the academic literature while adhering to the preferred reporting items for systematic reviews and meta-analyses (PRISMA)guidelines on four scientific databases including EMBASE, CENTRAL, Scopus, and MEDLINE. We performed a meta-analysis to evaluate the prevalence and severityof OSA. Severity was defined by apnea-hypopnea index (AHI)as mild (AHI ≥ 5 to < 15/h), moderate (AHI ≥ 15 to < 30/h), and severe (AHI ≥ 30/h).

From 1397 studies, we found 10 eligible studies with 569 patients with ILD (mean age 65.3 ± 6.0 years). Among these patients, 332 (61%) suffered from OSAwith 32% categorized as mild, 17% moderate, and 9% severe. CONCLUSION This systematic review and meta-analysis provides preliminary evidence regarding the high prevalence of OSA in ILD.
From 1397 studies, we found 10 eligible studies with 569 patients with ILD (mean age 65.3 ± 6.0 years). Among these patients, 332 (61%) suffered from OSA with 32% categorized as mild, 17% moderate, and 9% severe. CONCLUSION This systematic review and meta-analysis provides preliminary evidence regarding the high prevalence of OSA in ILD.
Nasal masks are usually the first choice for CPAP therapy, but patients may experience side effects. There are limited data regarding the efficacy of nasalpillows masks during CPAP titration. This study aimed to compare the polysomnography outcomes during CPAP titration while comparing two types of masks (nasal and pillows) and toassess whether or notthe patient characteristics differed between mask preferences.

In a sleep-disorders clinic, we prospectively analyzed all patients undergoingCPAP titration for three consecutive months. CPAP pressures were manually titrated. Anthropometric data (age, sex, body mass index, and neck and waist circumferences) and OSA severity were documented. Patients completed a self-administered questionnaire that measured nasal obstruction (NOSE scale). Before titration, both types of masks were presented to patients, and each of them chose the one they preferred.

Of 157 patients,55% (n = 86) used nasal masks, and 45% (n = 71) used nasalpillows masks. There was no difference according to mask type chosen by age, sex, body mass index, neck and waist circumferences, and NOSE scale. Polysomnography outcomes were similar between the mask groups. https://www.selleckchem.com/products/ami-1.html The mean CPAP level was 9.4 ± 1.8 cm H
O for nasal masks and 9.1 ± 2.0 cm H
O for nasalpillows (p = 0.61). Residual apnea-hypopnea index was 3.0 ± 2.8 events/h for nasal mask and 3.5 ± 4.1 events/h for pillow mask (p = 0.28). Baseline AHI, body mass index, neck and waist circumferences, and residual AHI were independent predictors of a higher CPAP pressure for both groups (p < 0.0001).

Nasal pillows masks seem to be as effective as nasal masks and may be considered to be an initial choice for CPAP titration.
Nasal pillows masks seem to be as effective as nasal masks and may be considered to be an initial choice for CPAP titration.