11/14/2024


This presentation gives a knowledge that the position and numbers of hydroxyl groups are pivotal to the degradation efficiency toward TCs.This study evaluates health risks associated with Arsenic due to mining activities in parts of North-central Nigeria. 306 samples of soil, water and guinea corn were collected for analysis using Atomic Absorption Spectrometry. https://www.selleckchem.com/products/Simvastatin(Zocor).html The analysis reveals varying concentration of Arsenic that is in most cases, above the acceptable limits of consumption, signifying evidence of pollution. The estimated pollution evaluation indices indicates evidence of pollution due to the mining activities. The estimated values of the bioaccumulation factors are very low. The Average Daily Intake reveals that ingestion pathway is the dominant pathway of exposure. While most of the Hazard Index (HI) estimated for the soil and grain samples are « 1, the HI estimated for the water is ≈1. This therefore, means that the probable non-cancerous effect of Arsenic in the drinking water is high. Based on the Delphii method of classification, the Incremental Lifetime Cancer Risk ranges between level II and level III for the soil and grain samples and between level VI and level VII for the water samples within the study sites. This high cancer risks was confirmed by the mean, 5th and 95th percentiles of the cumulative probabilities using the Monte Carlo simulation.The presence of aromatic compounds with multiple functional groups such as 5-sulfosalicylic acid (SSA) in water bodies is a threat to aquatic organisms and human health. Phenol (PH) with the -OH group, benzoic acid with -COOH and benzenesulfonic acid (BSA) with -SO3H can be considered as SSA structural unit. In this study, three functional monomers, namely, N-methylallylamine, diallylamine, and triallylamine, with strong affinity for PH, BA, and BSA, respectively, were selected from 16 monomers by using density functional theory (DFT). Molecularly imprinted resin (MIP-4) with tri-functional groups and excellent selectivity for SSA was synthesized using a macroporous polystyrene resin (NDA-1800) as the carrier. In binary systems, MIP-4 exhibited excellent imprinting effect and adsorption selectivity for SSA. X-ray spectroscopy data and DFT calculations illustrated that the adsorption of SSA on MIP-4 was mainly dependent on the strong electrostatic interaction between the protonated amine group on the resin and -SO3- of SSA, as well as, the hydrogen bond between the neutral amine group and -OH and -COOH of SSA; the order of the three functional groups in identification was -OH > -COOH > -SO3H. In addition, the adsorption performance of MIP-4 was retained after five adsorption-desorption cycles.The different physical-chemical properties of the black ash (200-500 °C) and white ash (>510 °C) generated by wildfire may result in varied impacts on soil biological and abiotic indicators. Many studies have highlighted the environmental impacts of wood ash application due to its complex mixture of beneficial and detrimental compounds. However, few studies have compared the effect of black ash and white ash on soil, especially for the heavy metal polluted soil. In this study, we used the comparative analysis of parallel microcosm experiments to study the impacts of white ash and black ash on bioavailable heavy metals and metabolic potentials of microbial community. The results indicated that both white ash and black ash increased the concentration of soil bioavailable As and Cr, while the increasing trend of bioavailable As could be limited by Ca in the treatment of white ash. The addition of black ash could enhance the abundance of genes related to the Calvin cycle (CBB). Different kinds of wood ash inputs into soils could cause the differences in the microbial taxa for carbon fixation, as indicated by the dominance of different taxa for carbon fixation in white ash versus black ash treatments. Additionally, both white ash and black ash impaired dissimilatory nitrate reduction to ammonium (DNRA), nitrate assimilation and nitrification, while white ash enhanced denitrification.Silica nanoparticles (SiNPs) have drawn considerable attention due to their environmental health effects, while enhanced understanding of metabolic disorders has provided insight into related diseases. To investigate the impacts of SiNPs exposure on reproduction and reveal their pathogenic mechanisms, this study was designed and conducted from a metabolic perspective. First, fluorescein isothiocyanate (FITC)-SiNPs were chemically synthesized and applied to track SiNPs in vitro and in vivo. Next, 30 pregnant mice were intratracheally instilled with 1.25 mg of SiNPs/mouse, then sacrificed 24 h post-treatment. We found that SiNPs penetrated the trophoblast membrane, triggering apoptosis and inhibiting cell proliferation, invasion, and tube formation in a dose-dependent manner. Mechanistically, SiNPs dysregulated phosphofructokinase (Pfkl) and fructose-bisphosphatase 2 (Fbp2) and induced glucose depletion and pyruvate accumulation via the pentose phosphate pathway. Besides, the downregulation of caspase-3 suggested a causal relationship between pyruvate accumulation, pentose phosphate pathway activation, and cell apoptosis. Pfkl and Fbp2 was also dysregulated in vivo, and the uterine inflammation aggravated in a time-dependent manner. In conclusion, SiNPs triggered acute cytotoxicity and uterine inflammation by inducing glucose depletion and pyruvate overload in trophoblasts, which were mediated in part by Pfkl and Fbp2 via the pentose phosphate pathway.A comprehensive study was presented on the ecological risk, distribution, and quantitative source apportionment of heavy metals in the selected lacustrine systems of Schirmacher Hills using various environmental indices and methods. A total of 25 sediment samples from 16 lakes were collected around scientific research stations and analyzed for metals. Geochemical approaches and ecological risk assessment methods were implemented to characterize and evaluate the contamination level and associated risk in the lacustrine systems. Moreover, statistical techniques and a positive matrix factorization (PMF) model were indorsed to understand metals' association and apportion their probable sources. Results revealed that most of the heavy metals (mean concentration in ppm) such as Al (77,504.09), Cd (1.36), Co (29.52), Cr (102.75), Cu (65.19), Fe (57,632.87), Mn (679.05), Ni (49.13), Pb (10.11), and Zn (253.78) are originated from natural weathering of source rocks (78.53%) followed by human-induced actions/ station activities coupled with atmospheric deposition (21.