py as an adjunct to it. Also, it is a safer, cost effective, less arduous, and patient friendly means of treating the disease.
Polishing of dental composite restorations to achieve a highly smooth and reflective surface not only enhances esthetics but also their color stability and improves resistance to staining. The objective of this study was to evaluate the effect of beverages on the color stability of nanoceramic composites polished using different techniques.

80 samples of ceram. X SphereTEC one were prepared by condensing the material into a stainless-steel split mold and divided randomly into two groups. Group I was subjected to polishing using Sof-Lex system™ disks, and Group II was kept unpolished. Each group was subdivided into four sub-groups of 10 samples each. Each subgroup samples were immersed into designated beverages (Tropicana orange juice, Coco-cola, Nescafe coffee, and distilled water) for a duration of 15mins/day for 15 days. The color of all specimens before immersion, one day, and 15 days after immersion was measured using a Spectrophotometer.

Significant staining of the material was found with cola drinks and coffee compared to orange juice and distilled water. Polished material showed better resistance to staining by various beverages compared to control group.

Nanoceramic composites exhibited superior color stability after polishing with Sof-Lex system™. Among the beverages, coco-cola significantly altered the color of the composite.
Nanoceramic composites exhibited superior color stability after polishing with Sof-Lex system™. Among the beverages, coco-cola significantly altered the color of the composite.
The ultimate goal of tissue engineering is to reproduce functional alveolar∖Periodontal complex. This study aimed to asses micro- and nano-formulated crystalline calcium sulfate as possible treatment of intrabony defect utilizing an autologous Platelet rich fibrin scaffold.

and Methods An experimental prospective split mouth design using eight healthy mongrel dog's was conducted. After two months of extracting the first premolar, bilateral intrabony defects were created mesial to the mandibular second premolar. One side was grafted by nanocrystalline calcium sulfate, while, the opposite side was grafted with microcrystalline calcium sulfate graft. Dogs were randomly euthanized after one month (group I) and 3 months (group II). The primary outcomes were the histological changes of new bone formation in hematoxylin and eosin and Masson trichrome stains, while histomorphometric and radiographic analysis were the secondary outcome followed by statistical analysis (P value was set at .05).

There was a significant increase in the percentage of bone formation in relation to defect height in nanocrystalline compared to microcrystalline form after one month and three months in both histological (p-values of <0.0001) and radiographic results (p-values of <0.0001).

Nanocrystalline calcium sulfate presented a significant enhanced periodontal regeneration compared to the microcrystalline form.
Nanocrystalline calcium sulfate presented a significant enhanced periodontal regeneration compared to the microcrystalline form.
To assess the correlation between the diameter of the mandibular lingual vascular canal (MLVC) as determined on CBCT examination to blood flow and arterial diameter as determined by ultrasound Doppler analysis (USG) in dentate and edentulous patients.

20 subjects were equally distributed into two groups based on the status of their dentition. Group 1 included dentate subjects (DE) and Group 2 included edentulous subjects (ED).The subjects from both the groups underwent CBCT scan for the assesement of the diameter of the MLVC.Similarly, USG was done to assess the diameter of the sublingual artery anastomosis and blood flow in the anterior mandible. Data was analysed using Karl Pearson's Correlation coefficient test and Student's unpaired 't' test.

Irrespective of the status of the dentition and age, a positive correlation was noted between the diameter of foramen on CBCT examination and the diameter of anastomosing artery as studied by the USG (r​=​0.290).Similarly, a positive correlation was observed between the diameter of foramen on CBCT and the volume of blood entering the mandible (r​=​0.447).A positive correlation (r​=​0.138) was observed between the diameter of the anastomosing artery and the volume of blood entering the mandible.

The anterior mandible has a rich vascular supply independent of age and status of the dentition.The dimensions and location of MVLC could be assessed on a CBCT prior to implant placement so that the operating surgeon has an idea about the vascularity of the region. Further studies with higher sample size should be undertaken to confirm these findings.
The anterior mandible has a rich vascular supply independent of age and status of the dentition.The dimensions and location of MVLC could be assessed on a CBCT prior to implant placement so that the operating surgeon has an idea about the vascularity of the region. https://www.selleckchem.com/products/LY294002.html Further studies with higher sample size should be undertaken to confirm these findings.
Oral squamous cell carcinoma (OSCC) still lacks the valid prognosticator for survival. Tumor associated tissue eosinophilia (TATE) have been widely investigated in the literature but still there is no consensus viewpoint on its role as prognostic marker. With this view in mind, a systematic review and meta-analysis of studies that evaluated the overall risk of elevated TATE and survival in OSCC was conducted


A systematic literature search conducted to identify studies that have evaluated TATE in OSCC. Overall survival (OS), Disease Free Survival (DFS) Hazard ratio (HR) with 95% confidence interval) was extracted. HR was extrapolated if direct HR was not given in publication. Studies were pooled and combined hazard ratios (HRs) of High TATE for OS and DFS were calculated.

6 out of 874 articles were found eligible for systematic review and meta-analysis. High TATE was predictor of OS (
HR 0.45 (95% CI, 030-0.65,
​<​0.0001)) and DFS (
HR 2.33 (95% CI, 0.74-7.37)) in OSCC patients.

High TATE positively predicts OS and DFS in OSCC and thus can be regarded as an important survival prognosticator.