"Interestingly, these researchers could recapitulate the effects of the virus on mast cell degranulation with just the Spike protein binding to the ACE2 receptor on mast cells. This makes their findings relevant not only to the impact of COVID infection, but also to the impact of COVID vaccines..."
https://immunologyfordailyliving.substack.com/p/spike-protein-and-mast-cell-activation?s=r
Perhaps one of the most puzzling aspects of COVID-19 is its dichotomy between asymptomatic/mild cases and an unusual (for a viral illness) hyper-inflammatory symptomatology of severe cases. Here, I would like to draw the connections between a triad of players, which may explain the puzzle: the Spike protein, mast cells, and vitamin D.
immunologyfordailyliving.substack.com
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