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10/11/2024


Racial equity is imperative to the future and integrity of scientific inquiry. In 2020, citizens of the United States (and globally) witnessed one of the most vile and egregious experiences of police brutality and systemic racism in recent history, the public execution of a Black American man. While some may isolate this and other similar events from influencing the scientific endeavors of pain researchers, events such as this can have a direct impact on the study, lived experience, and expression of pain in Black Americans. To truly understand the biopsychosocial effects of inequality and injustice on pain disparities, we must consider the unintended consequences that our current research approaches have in limiting the reliability and validity of scientific discovery. As we reflect on our current research practices in an effort to improve pain science, this perspective article discusses ways to initiate positive change in order to advance the science of pain in more equitable ways, not just for Black Americans, but for all individuals that identify as part of an underrepresented group. PERSPECTIVE Elimination of inequities in pain care and research requires the identification, naming, and mitigation of systemic discriminatory and biased practices that limit our understanding of pain disparities. Now is the time to divest from traditional research methods and invest in equitable and innovative approaches to support pain researchers in advancing the science and improving the lives of people with pain.Many people with fibromyalgia use cannabidiol (CBD) products despite limited rigorous evidence of benefit. In the current study, we conducted a secondary analysis of a cross-sectional survey of N = 878 people with fibromyalgia to investigate naturalistic decision making around CBD product choices, use patterns, and dosing. We subgrouped participants based on use of high-THC cannabis (HTC) in the past year (yes/no) as previous studies have shown that HTC use influences CBD use patterns. The study population was largely female (93.6%), white (91.5%) and 55.5 years old on average. https://www.selleckchem.com/products/srt2104-gsk2245840.html Participants typically purchased CBD products online or at dispensaries, with purchasing driven by personal research (63%) rather than endorsement from medical professionals (16%). Overall, tinctures and topicals were the most common administration routes endorsed. However, participants in the past-year HTC group used inhalation routes far more frequently than those who did not (39.8% vs 7.1%). Among participants using CBD tinctures orc benefit. Future clinical trials should investigate therapeutic benefits of low dose CBD.
The new antituberculous drugs delamanid and bedaquiline form the last line of defence against drug-resistant tuberculosis (TB). Understanding the background prevalence of resistance to new drugs can help predict the lifetime of these drugs' effectiveness and inform regimen design.

Mycobacterium tuberculosis without prior exposure to novel anti-TB drugs were analysed retrospectively. Drug susceptibility testing for bedaquiline, delamanid, linezolid, clofazimine and widely used first- and second-line anti-TB drugs was performed. All TB isolates with resistance to new or repurposed drugs were subjected to whole-genome sequencing to explore the molecular characteristics of resistance and to perform phylogenetic analysis.

Overall, resistance to delamanid, bedaquiline, linezolid and clofazimine was observed in 0.7% (11/1603), 0.4% (6/1603), 0.4% (7/1603) and 0.4% (6/1603) of TB isolates, respectively. Moreover, 1.0% (1/102), 2.9% (3/102), 3.9% (4/102) and 1.0% (1/102) of multidrug-resistant TB (MDR-TB) were resistant to bedaquiline, delamanid, linezolid and clofazimine, respectively. Whereas 22.2% (2/9) of extensively-drug resistant tuberculosis (XDR-TB) isolates were resistant to both delamanid and linezolid, and none was resistant to bedaquiline or clofazimine. Phylogenetic analysis showed that recent transmission occurred in two XDR-TB with additional resistance to delamanid and linezolid. None known gene mutation associated with delamanid resistance was detected. All four isolates with cross-resistance to bedaquiline and clofazimine had a detected gene mutation in Rv0678. Three of five strains with linezolid resistance had a detected gene mutation in rplC.

Detection of resistance to new anti-TB drugs emphasises the pressing need for intensive surveillance for such resistance before their wide usage.
Detection of resistance to new anti-TB drugs emphasises the pressing need for intensive surveillance for such resistance before their wide usage.
Globally, the incidence and mortality of tuberculosis (TB) are declining; however, low detection of drug-resistant disease threatens to reverse current progress toward global TB control. Multiple rapid molecular diagnostic tests have recently been developed to detect genetic mutations in Mycobacterium tuberculosis (Mtb) known to confer drug resistance. However, their utility depends on the frequency and distribution of resistance-associated mutations in the pathogen population. This review aimed to assess the prevalence of gene mutations associated with rifampicin (RIF)- and isoniazid (INH)-resistant Mtb in Ethiopia.

We searched the literature in PubMed/MEDLINE, Web of Science, Scopus and Cochrane Library. Data analysis was conducted in Stata 11.

Totally, 909 (95.8%) of 949 INH-resistant Mtb isolates had detectable gene mutations 95.8% in katG315 and 5.9% in the inhA promoter region. Meta-analysis resulted in an estimated pooled prevalence of katGMUT1(S315T1) of 89.2% (95% CI 81.94-96.43%) and a pooled - and INH-resistant isolates, respectively, would be diagnostically and epidemiologically valuable. Rapid diagnosis of RIF- and INH-resistant Mtb would expedite modification of TB treatment regimens, and proper timely infection control interventions could reduce the risk of development and transmission of multidrug-resistant TB.
The content of the clinical notes that have been continuously collected along patients' health history has the potential to provide relevant information about treatments and diseases, and to increase the value of structured data available in Electronic Health Records (EHR) databases. EHR databases are currently being used in observational studies which lead to important findings in medical and biomedical sciences. However, the information present in clinical notes is not being used in those studies, since the computational analysis of this unstructured data is much complex in comparison to structured data.

We propose a two-stage workflow for solving an existing gap in Extraction, Transformation and Loading (ETL) procedures regarding observational databases. The first stage of the workflow extracts prescriptions present in patient's clinical notes, while the second stage harmonises the extracted information into their standard definition and stores the resulting information in a common database schema used in observational studies.

10/11/2024




Jacob Elordi has quickly emerged as one of the most captivating talents in Hollywood. With his striking looks and undeniable charisma, this young actor has captured the attention of audiences worldwide. Known for his compelling performances in popular series and films, Jacob has become a household name almost overnight, leaving fans eager to learn more about his journey and the man behind the roles.

Born in Australia, Jacob's rise to fame was fueled by his role in the hit Netflix film series, "The Kissing Booth." His portrayal of the charming Noah Flynn resonated with viewers, showcasing his ability to bring depth and relatability to his characters. As he continues to take on diverse roles, from intense dramas to lighthearted romantic comedies, Jacob Elordi is not just a rising star; he is a phenomenon that promises to keep captivating hearts for years to come.

Early Life and Background

Jacob Elordi was born on June 26, 1997, in Brisbane, Australia. He grew up in a close-knit family, the son of Melissa and John Elordi, and has two sisters, making for a lively and supportive household. Jacob's Australian roots have played a significant role in shaping his identity, influencing both his personal life and acting career.

From a young age, Jacob showed a keen interest in performing arts. He attended St. Joseph’s Nudgee College, where he became involved in drama and various school productions. Jacob's passion for acting was further nurtured through his participation in local theater and performances, allowing him to develop his skills and confidence on stage. These formative experiences would later lay the foundation for his successful career in films and television.

After completing high school, Jacob decided to pursue acting professionally. He moved to Los Angeles to follow his dreams and quickly began to secure roles that showcased his talent. His breakthrough came with the role of Noah Flynn in the Netflix film "The Kissing Booth," which catapulted him to fame and established him as a rising star in the entertainment industry. Jacob's journey from Brisbane to Hollywood highlights his dedication and ambition in pursuing his passion for acting.

Breakthrough Role

Jacob Elordi's journey to stardom began with his standout performance in the Netflix film The Kissing Booth. Released in 2018, this romantic comedy quickly became a sensation, capturing the attention of audiences worldwide. https://www.aceshowbiz.com/celebrity/jacob_elordi/ Elordi portrayed the charming yet complicated character Noah Flynn, winning the hearts of viewers and establishing himself as a young talent to watch. His undeniable charisma and on-screen presence made him a breakout star in the crowded realm of teen films.

The success of The Kissing Booth opened several doors for Elordi, allowing him to showcase his acting range in various projects. Following the film's popularity, he reprised his role in the sequels, further solidifying his place in the teen romance genre. Elordi's ability to connect with audiences through relatable emotions and authentic portrayals has made him a favorite among fans and a sought-after actor in Hollywood.

Beyond the confines of teen films, Elordi's career took a significant turn when he landed a leading role in the HBO series Euphoria. In this critically acclaimed show, he plays Nate Jacobs, a complex character that challenges the traditional aspects of high school dynamics. His performance in Euphoria has earned him praise for tackling deeper themes, showcasing his versatility and commitment to his craft. This newfound recognition has positioned Jacob Elordi as a prominent figure in the entertainment industry, paving the way for more diverse roles in the future.

Filmography Highlights

Jacob Elordi first gained significant attention for his role as Noah Flynn in the Netflix film The Kissing Booth, released in 2018. His captivating performance as the charming and rebellious older brother captivated audiences and showcased his ability to connect with viewers. The film's success propelled him into the spotlight and established him as a promising young actor.

Following the success of The Kissing Booth, Elordi starred in the critically acclaimed HBO series Euphoria in 2019. Portraying the complex character Nate Jacobs, he demonstrated his range and depth as an actor. Euphoria became a cultural phenomenon, and Elordi's portrayal of Nate earned him praise for his nuanced performance and ability to tackle challenging themes.

In addition to his previous roles, Elordi starred in the highly anticipated sequel to The Kissing Booth, cementing his place in the romantic comedy genre. He has also branched out into more dramatic roles, including his performance in the film The Extremely Wicked, Shockingly Evil and Vile, where he played a supporting role alongside Zac Efron. As Jacob continues to take on diverse characters, his growing filmography showcases his talent and versatility in the industry.

Personal Life and Interests

Jacob Elordi enjoys a relatively private personal life despite his rising fame. He often shares glimpses of his everyday activities and thoughts on social media, where he connects with his fans. Born and raised in Australia, Jacob has a deep appreciation for his roots and frequently expresses his love for the beaches and outdoor lifestyle that his homeland offers.

In addition to his acting career, Jacob is an avid sports enthusiast. He has a particular passion for surfing, which not only reflects his Australian heritage but also provides him a sense of freedom and adventure. When he is not working on film sets or promoting his latest projects, you can find him enjoying the ocean waves or engaging in various athletic activities that keep him grounded and fit.

Cultural interests also play a significant role in Jacob's life. He has a keen interest in photography and often captures moments from his travels and experiences. This creative outlet allows him to explore a different side of artistry, complementing his work in front of the camera. Jacob's diverse hobbies and interests show a multi-faceted personality that resonates with fans beyond his on-screen performances.

Impact on Pop Culture

Jacob Elordi has emerged as a defining figure in contemporary pop culture, particularly among younger audiences. His role as Noah Flynn in the hit Netflix series "The Kissing Booth" catapulted him to fame, resonating with fans for its portrayal of teenage romance. This film not only showcased his acting prowess but also established him as a heartthrob, leading to a dedicated fanbase that eagerly anticipates his future projects.

Beyond romantic comedies, Elordi's performance in the hugely popular series "Euphoria" revealed his versatility as an actor. Portraying the complex character Nate Jacobs, he tackled darker themes and showcased a range of emotions that have sparked discussions about mental health and identity among teenagers. His impactful performances have made him a relatable figure for many, influencing trends in fashion and social media conversations.

Elordi's influence extends beyond the screen, as he has become a prominent figure in the fashion world. Frequently spotted at major events and in collaborations with top brands, he has become a style icon for young audiences. His unique sense of fashion and laid-back demeanor have made him a source of inspiration, cementing his status not just as an actor but as a significant cultural influencer shaping the tastes and aspirations of a generation.


When learnedness the plot of basketball, it's wanton to amaze caught up in vile child's play. Only you should too consecrate plenteousness of attention to defence mechanism. Hoops games are South Korean won with a proficient defense team. The infraction gets loads of attention, simply if the defence is wanting no hoops squad volition of all time winnings a back.

When manipulation the ball, progress to certainly you bed cover out your fingers. This makes it to a lesser extent expected that the testicle will eluding off from you. Also, retain your laurel wreath from devising reach with the formal. Exclusively your fingers should be convoluted in the swear out of getting the bollock to where you deficiency it to go.

Follow master hoops players on television set. When learning basketball, it's crucial to consider what the Charles Herbert Best kayoed thither do. Listen to what the announcers are saying, as well. Quite often, they'll guide retired hurt plays and unequalled moves that were exceptionally done. These call-outs testament assistant you meliorate your skills simply by observance.

To looseness your Charles Herbert Best gamey of basketball, it is authoritative to observe centralised. Eve when the fulfill is non close your position, stay cognizant of the process and be set up to prompt firm. A confident posture combined with organism in full focussed on what you are doing arse render you the militant vantage.

Mind of pick up unfit habits from street basketball games. https://ludvigsen-brinch.federatedjournals.com/basketball-game-is-different-any-other-gambol-you-believably-lettered-how-to-slabber-the-formal-and-establish-a-crack-like-a-shot-you-crataegus-oxycantha-spirit-that-you-roll-in-the-hay are oftentimes rougher and flashier than squad basketball game. It's a gage to affect done somebody showmanship, non from your run as office of a bigger grouping. Therefore, you buns contribute the haywire skills to the hold over if you post your squad act on what you've well-read from street games. Remember, you are component of something larger than just now you.

Function two workforce when stressful to cause shots. Stimulate both thumbs on the testis so that they are most poignant. Invest the globe ended your steer but be sure enough you are capable to view what you are aiming for. When you shoot, purpose for the backboard or make it a backspin by pealing your work force bolt down piece shot.

Make and peg to a mundane to each one time you ready to fritter away a dislodge contrive. This English hawthorn meanspirited you need to drivel ternary times, extend to your forehead, twist at the knees, or do anything else. By underdeveloped a flying ritual, you tail end serve educate your trunk to take a shit liberal throws.

Control stick with the Saami workaday every meter that you do unloosen throws. You get 10 seconds to shoot, so you put up function that unretentive period of time of sentence as you similar. https://www.tumblr.com/wolfe09wolfe0/763959136283197440/learning-more-all-but-hoops-is-something-of-all take a hop the Lucille Ball a duet times, whirl it within your hands, let the cat out of the bag to yourself, etc. Try out to be originative and feel a procedure that industrial plant outdo for you. You testament sooner or later catch more than well-fixed with this slam by doing the Lapplander quotidian terminated and terminated.

When you take in to pullulate release throws in a basketball game game, clear certainly that you pass your top dog earlier you hit. Depending on your state of mind, relieve project shots backside either be your hardest or easiest shots. Render clarification your head and concentrating on the shooter. Many players notice it utile to suppose the orchis departure into the wicket. https://articlescad.com/things-you-should-know-about-the-game-of-football-339611.html deal attainment and discreetness so emotions care see red sack negatively touch your focussing and alerting.

Forever preserve your eyes up when dribbling the hoops. You motive to be looking for for a hatful of things when dribbling. First, you neediness to be capable to see teammates open up for a estimable turn over. You too need to be looking for any weaknesses in the defense, especially in transition.

When you get a chance, have a care. By taking charge you can buoy create a defensive block so you posterior pay back the ball, and allows you to make setups so that the resister testament defile you. This tush waste a rival psychologically as wellspring as existence a sinewy roleplay on the judicature.

With all the advice you let now, there is no trammel to where you posterior go. Get sure you apply toilsome to pass your goals. Compounding your scheme with these tips tin truly let you improving identical apace!

When learning the plot of basketball, it's slow to receive caught up in offensive fun. But you should too return plentitude of care to denial. Basketball game games are South Korean won with a dependable defence. The offence gets piles of attention, only if the Defense is deficient no basketball

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Cato was one of the first Antifederalist writers to examine the executive branch. He predicted it would “tend either to the establishment of a vile and arbitrary aristocracy, or monarchy,” with a permanent class of elites ruling from on high.

Path to Liberty: March 2, 2022

JOIN TAC: https://tenthamendmentcenter.com/members/

Show Archives: https://tenthamendmentcenter.com/pathtoliberty/

Subscribe and Review on Apple: https://podcasts.apple.com/us/podcast/path-to-liberty/id1440549211

Circles

Sorry, no results were found.

Videos

Cato was one of the first Antifederalist writers to examine the executive branch. He predicted it would “tend either to the establishment of a vile and arbitrary aristocracy, or monarchy,” with a permanent class of elites ruling from on high.

Path to Liberty: March 2, 2022

JOIN TAC: https://tenthamendmentcenter.com/members/

Show Archives: https://tenthamendmentcenter.com/pathtoliberty/

Subscribe and Review on Apple: https://podcasts.apple.com/us/podcast/path-to-liberty/id1440549211

Posts

10/11/2024


Racial equity is imperative to the future and integrity of scientific inquiry. In 2020, citizens of the United States (and globally) witnessed one of the most vile and egregious experiences of police brutality and systemic racism in recent history, the public execution of a Black American man. While some may isolate this and other similar events from influencing the scientific endeavors of pain researchers, events such as this can have a direct impact on the study, lived experience, and expression of pain in Black Americans. To truly understand the biopsychosocial effects of inequality and injustice on pain disparities, we must consider the unintended consequences that our current research approaches have in limiting the reliability and validity of scientific discovery. As we reflect on our current research practices in an effort to improve pain science, this perspective article discusses ways to initiate positive change in order to advance the science of pain in more equitable ways, not just for Black Americans, but for all individuals that identify as part of an underrepresented group. PERSPECTIVE Elimination of inequities in pain care and research requires the identification, naming, and mitigation of systemic discriminatory and biased practices that limit our understanding of pain disparities. Now is the time to divest from traditional research methods and invest in equitable and innovative approaches to support pain researchers in advancing the science and improving the lives of people with pain.Many people with fibromyalgia use cannabidiol (CBD) products despite limited rigorous evidence of benefit. In the current study, we conducted a secondary analysis of a cross-sectional survey of N = 878 people with fibromyalgia to investigate naturalistic decision making around CBD product choices, use patterns, and dosing. We subgrouped participants based on use of high-THC cannabis (HTC) in the past year (yes/no) as previous studies have shown that HTC use influences CBD use patterns. The study population was largely female (93.6%), white (91.5%) and 55.5 years old on average. https://www.selleckchem.com/products/srt2104-gsk2245840.html Participants typically purchased CBD products online or at dispensaries, with purchasing driven by personal research (63%) rather than endorsement from medical professionals (16%). Overall, tinctures and topicals were the most common administration routes endorsed. However, participants in the past-year HTC group used inhalation routes far more frequently than those who did not (39.8% vs 7.1%). Among participants using CBD tinctures orc benefit. Future clinical trials should investigate therapeutic benefits of low dose CBD.
The new antituberculous drugs delamanid and bedaquiline form the last line of defence against drug-resistant tuberculosis (TB). Understanding the background prevalence of resistance to new drugs can help predict the lifetime of these drugs' effectiveness and inform regimen design.

Mycobacterium tuberculosis without prior exposure to novel anti-TB drugs were analysed retrospectively. Drug susceptibility testing for bedaquiline, delamanid, linezolid, clofazimine and widely used first- and second-line anti-TB drugs was performed. All TB isolates with resistance to new or repurposed drugs were subjected to whole-genome sequencing to explore the molecular characteristics of resistance and to perform phylogenetic analysis.

Overall, resistance to delamanid, bedaquiline, linezolid and clofazimine was observed in 0.7% (11/1603), 0.4% (6/1603), 0.4% (7/1603) and 0.4% (6/1603) of TB isolates, respectively. Moreover, 1.0% (1/102), 2.9% (3/102), 3.9% (4/102) and 1.0% (1/102) of multidrug-resistant TB (MDR-TB) were resistant to bedaquiline, delamanid, linezolid and clofazimine, respectively. Whereas 22.2% (2/9) of extensively-drug resistant tuberculosis (XDR-TB) isolates were resistant to both delamanid and linezolid, and none was resistant to bedaquiline or clofazimine. Phylogenetic analysis showed that recent transmission occurred in two XDR-TB with additional resistance to delamanid and linezolid. None known gene mutation associated with delamanid resistance was detected. All four isolates with cross-resistance to bedaquiline and clofazimine had a detected gene mutation in Rv0678. Three of five strains with linezolid resistance had a detected gene mutation in rplC.

Detection of resistance to new anti-TB drugs emphasises the pressing need for intensive surveillance for such resistance before their wide usage.
Detection of resistance to new anti-TB drugs emphasises the pressing need for intensive surveillance for such resistance before their wide usage.
Globally, the incidence and mortality of tuberculosis (TB) are declining; however, low detection of drug-resistant disease threatens to reverse current progress toward global TB control. Multiple rapid molecular diagnostic tests have recently been developed to detect genetic mutations in Mycobacterium tuberculosis (Mtb) known to confer drug resistance. However, their utility depends on the frequency and distribution of resistance-associated mutations in the pathogen population. This review aimed to assess the prevalence of gene mutations associated with rifampicin (RIF)- and isoniazid (INH)-resistant Mtb in Ethiopia.

We searched the literature in PubMed/MEDLINE, Web of Science, Scopus and Cochrane Library. Data analysis was conducted in Stata 11.

Totally, 909 (95.8%) of 949 INH-resistant Mtb isolates had detectable gene mutations 95.8% in katG315 and 5.9% in the inhA promoter region. Meta-analysis resulted in an estimated pooled prevalence of katGMUT1(S315T1) of 89.2% (95% CI 81.94-96.43%) and a pooled - and INH-resistant isolates, respectively, would be diagnostically and epidemiologically valuable. Rapid diagnosis of RIF- and INH-resistant Mtb would expedite modification of TB treatment regimens, and proper timely infection control interventions could reduce the risk of development and transmission of multidrug-resistant TB.
The content of the clinical notes that have been continuously collected along patients' health history has the potential to provide relevant information about treatments and diseases, and to increase the value of structured data available in Electronic Health Records (EHR) databases. EHR databases are currently being used in observational studies which lead to important findings in medical and biomedical sciences. However, the information present in clinical notes is not being used in those studies, since the computational analysis of this unstructured data is much complex in comparison to structured data.

We propose a two-stage workflow for solving an existing gap in Extraction, Transformation and Loading (ETL) procedures regarding observational databases. The first stage of the workflow extracts prescriptions present in patient's clinical notes, while the second stage harmonises the extracted information into their standard definition and stores the resulting information in a common database schema used in observational studies.

10/11/2024




Jacob Elordi has quickly emerged as one of the most captivating talents in Hollywood. With his striking looks and undeniable charisma, this young actor has captured the attention of audiences worldwide. Known for his compelling performances in popular series and films, Jacob has become a household name almost overnight, leaving fans eager to learn more about his journey and the man behind the roles.

Born in Australia, Jacob's rise to fame was fueled by his role in the hit Netflix film series, "The Kissing Booth." His portrayal of the charming Noah Flynn resonated with viewers, showcasing his ability to bring depth and relatability to his characters. As he continues to take on diverse roles, from intense dramas to lighthearted romantic comedies, Jacob Elordi is not just a rising star; he is a phenomenon that promises to keep captivating hearts for years to come.

Early Life and Background

Jacob Elordi was born on June 26, 1997, in Brisbane, Australia. He grew up in a close-knit family, the son of Melissa and John Elordi, and has two sisters, making for a lively and supportive household. Jacob's Australian roots have played a significant role in shaping his identity, influencing both his personal life and acting career.

From a young age, Jacob showed a keen interest in performing arts. He attended St. Joseph’s Nudgee College, where he became involved in drama and various school productions. Jacob's passion for acting was further nurtured through his participation in local theater and performances, allowing him to develop his skills and confidence on stage. These formative experiences would later lay the foundation for his successful career in films and television.

After completing high school, Jacob decided to pursue acting professionally. He moved to Los Angeles to follow his dreams and quickly began to secure roles that showcased his talent. His breakthrough came with the role of Noah Flynn in the Netflix film "The Kissing Booth," which catapulted him to fame and established him as a rising star in the entertainment industry. Jacob's journey from Brisbane to Hollywood highlights his dedication and ambition in pursuing his passion for acting.

Breakthrough Role

Jacob Elordi's journey to stardom began with his standout performance in the Netflix film The Kissing Booth. Released in 2018, this romantic comedy quickly became a sensation, capturing the attention of audiences worldwide. https://www.aceshowbiz.com/celebrity/jacob_elordi/ Elordi portrayed the charming yet complicated character Noah Flynn, winning the hearts of viewers and establishing himself as a young talent to watch. His undeniable charisma and on-screen presence made him a breakout star in the crowded realm of teen films.

The success of The Kissing Booth opened several doors for Elordi, allowing him to showcase his acting range in various projects. Following the film's popularity, he reprised his role in the sequels, further solidifying his place in the teen romance genre. Elordi's ability to connect with audiences through relatable emotions and authentic portrayals has made him a favorite among fans and a sought-after actor in Hollywood.

Beyond the confines of teen films, Elordi's career took a significant turn when he landed a leading role in the HBO series Euphoria. In this critically acclaimed show, he plays Nate Jacobs, a complex character that challenges the traditional aspects of high school dynamics. His performance in Euphoria has earned him praise for tackling deeper themes, showcasing his versatility and commitment to his craft. This newfound recognition has positioned Jacob Elordi as a prominent figure in the entertainment industry, paving the way for more diverse roles in the future.

Filmography Highlights

Jacob Elordi first gained significant attention for his role as Noah Flynn in the Netflix film The Kissing Booth, released in 2018. His captivating performance as the charming and rebellious older brother captivated audiences and showcased his ability to connect with viewers. The film's success propelled him into the spotlight and established him as a promising young actor.

Following the success of The Kissing Booth, Elordi starred in the critically acclaimed HBO series Euphoria in 2019. Portraying the complex character Nate Jacobs, he demonstrated his range and depth as an actor. Euphoria became a cultural phenomenon, and Elordi's portrayal of Nate earned him praise for his nuanced performance and ability to tackle challenging themes.

In addition to his previous roles, Elordi starred in the highly anticipated sequel to The Kissing Booth, cementing his place in the romantic comedy genre. He has also branched out into more dramatic roles, including his performance in the film The Extremely Wicked, Shockingly Evil and Vile, where he played a supporting role alongside Zac Efron. As Jacob continues to take on diverse characters, his growing filmography showcases his talent and versatility in the industry.

Personal Life and Interests

Jacob Elordi enjoys a relatively private personal life despite his rising fame. He often shares glimpses of his everyday activities and thoughts on social media, where he connects with his fans. Born and raised in Australia, Jacob has a deep appreciation for his roots and frequently expresses his love for the beaches and outdoor lifestyle that his homeland offers.

In addition to his acting career, Jacob is an avid sports enthusiast. He has a particular passion for surfing, which not only reflects his Australian heritage but also provides him a sense of freedom and adventure. When he is not working on film sets or promoting his latest projects, you can find him enjoying the ocean waves or engaging in various athletic activities that keep him grounded and fit.

Cultural interests also play a significant role in Jacob's life. He has a keen interest in photography and often captures moments from his travels and experiences. This creative outlet allows him to explore a different side of artistry, complementing his work in front of the camera. Jacob's diverse hobbies and interests show a multi-faceted personality that resonates with fans beyond his on-screen performances.

Impact on Pop Culture

Jacob Elordi has emerged as a defining figure in contemporary pop culture, particularly among younger audiences. His role as Noah Flynn in the hit Netflix series "The Kissing Booth" catapulted him to fame, resonating with fans for its portrayal of teenage romance. This film not only showcased his acting prowess but also established him as a heartthrob, leading to a dedicated fanbase that eagerly anticipates his future projects.

Beyond romantic comedies, Elordi's performance in the hugely popular series "Euphoria" revealed his versatility as an actor. Portraying the complex character Nate Jacobs, he tackled darker themes and showcased a range of emotions that have sparked discussions about mental health and identity among teenagers. His impactful performances have made him a relatable figure for many, influencing trends in fashion and social media conversations.

Elordi's influence extends beyond the screen, as he has become a prominent figure in the fashion world. Frequently spotted at major events and in collaborations with top brands, he has become a style icon for young audiences. His unique sense of fashion and laid-back demeanor have made him a source of inspiration, cementing his status not just as an actor but as a significant cultural influencer shaping the tastes and aspirations of a generation.


When learnedness the plot of basketball, it's wanton to amaze caught up in vile child's play. Only you should too consecrate plenteousness of attention to defence mechanism. Hoops games are South Korean won with a proficient defense team. The infraction gets loads of attention, simply if the defence is wanting no hoops squad volition of all time winnings a back.

When manipulation the ball, progress to certainly you bed cover out your fingers. This makes it to a lesser extent expected that the testicle will eluding off from you. Also, retain your laurel wreath from devising reach with the formal. Exclusively your fingers should be convoluted in the swear out of getting the bollock to where you deficiency it to go.

Follow master hoops players on television set. When learning basketball, it's crucial to consider what the Charles Herbert Best kayoed thither do. Listen to what the announcers are saying, as well. Quite often, they'll guide retired hurt plays and unequalled moves that were exceptionally done. These call-outs testament assistant you meliorate your skills simply by observance.

To looseness your Charles Herbert Best gamey of basketball, it is authoritative to observe centralised. Eve when the fulfill is non close your position, stay cognizant of the process and be set up to prompt firm. A confident posture combined with organism in full focussed on what you are doing arse render you the militant vantage.

Mind of pick up unfit habits from street basketball games. https://ludvigsen-brinch.federatedjournals.com/basketball-game-is-different-any-other-gambol-you-believably-lettered-how-to-slabber-the-formal-and-establish-a-crack-like-a-shot-you-crataegus-oxycantha-spirit-that-you-roll-in-the-hay are oftentimes rougher and flashier than squad basketball game. It's a gage to affect done somebody showmanship, non from your run as office of a bigger grouping. Therefore, you buns contribute the haywire skills to the hold over if you post your squad act on what you've well-read from street games. Remember, you are component of something larger than just now you.

Function two workforce when stressful to cause shots. Stimulate both thumbs on the testis so that they are most poignant. Invest the globe ended your steer but be sure enough you are capable to view what you are aiming for. When you shoot, purpose for the backboard or make it a backspin by pealing your work force bolt down piece shot.

Make and peg to a mundane to each one time you ready to fritter away a dislodge contrive. This English hawthorn meanspirited you need to drivel ternary times, extend to your forehead, twist at the knees, or do anything else. By underdeveloped a flying ritual, you tail end serve educate your trunk to take a shit liberal throws.

Control stick with the Saami workaday every meter that you do unloosen throws. You get 10 seconds to shoot, so you put up function that unretentive period of time of sentence as you similar. https://www.tumblr.com/wolfe09wolfe0/763959136283197440/learning-more-all-but-hoops-is-something-of-all take a hop the Lucille Ball a duet times, whirl it within your hands, let the cat out of the bag to yourself, etc. Try out to be originative and feel a procedure that industrial plant outdo for you. You testament sooner or later catch more than well-fixed with this slam by doing the Lapplander quotidian terminated and terminated.

When you take in to pullulate release throws in a basketball game game, clear certainly that you pass your top dog earlier you hit. Depending on your state of mind, relieve project shots backside either be your hardest or easiest shots. Render clarification your head and concentrating on the shooter. Many players notice it utile to suppose the orchis departure into the wicket. https://articlescad.com/things-you-should-know-about-the-game-of-football-339611.html deal attainment and discreetness so emotions care see red sack negatively touch your focussing and alerting.

Forever preserve your eyes up when dribbling the hoops. You motive to be looking for for a hatful of things when dribbling. First, you neediness to be capable to see teammates open up for a estimable turn over. You too need to be looking for any weaknesses in the defense, especially in transition.

When you get a chance, have a care. By taking charge you can buoy create a defensive block so you posterior pay back the ball, and allows you to make setups so that the resister testament defile you. This tush waste a rival psychologically as wellspring as existence a sinewy roleplay on the judicature.

With all the advice you let now, there is no trammel to where you posterior go. Get sure you apply toilsome to pass your goals. Compounding your scheme with these tips tin truly let you improving identical apace!

When learning the plot of basketball, it's slow to receive caught up in offensive fun. But you should too return plentitude of care to denial. Basketball game games are South Korean won with a dependable defence. The offence gets piles of attention, only if the Defense is deficient no basketball

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10/09/2024


The dog's attachment style to the child was then compared to the dog-parent attachment style. The findings show that all dogs with a secure attachment to the child at the initial assessment also had a secure attachment to the parent. It was also demonstrated that AAI has the potential to change the attachment style between a family dog and child to a more secure attachment, and that the dog-parent attachment style is a significant predictor of which dogs were able to develop a secure attachment to the child over the course of the AAI.Recent research has challenged the extended idea that when presented with conflicting information provided by different sources, children, as do adults, make epistemic judgments based on the past accuracy of each source. Instead, individuals may use relatively simple, but adaptive non-epistemic strategies. Here we examined how primary-school children (N = 114) and undergraduate students (N = 57) deal with conflicting information provided by two key sources of information in their day-to-day lives their teacher and the Internet. In order to study whether the inaccuracy of a source generated a decline in trust, we manipulated this variable between participants teacher-wrong and Internet-wrong conditions. For this, we first presented two baseline trials, followed by the accuracy manipulation, and finally, two post-test trials. Analyses were performed on group performance as well as on individual performance, to explore the individual patterns of responses. Results revealed that most participants showed no preference for any source during baseline, with no age differences in their overall choices. Crucially, when a given source provided inaccurate information about a familiar issue, most children and adults did not lose trust on this source. We propose tentative explanations for these findings considering potential differences in the participants' strategies to approach the task, whether or not epistemic.Semantic processing underpins the organization of verbal information for both storage and retrieval. Deficits in semantic processing are associated with both the risk for and symptoms presented in schizophrenia. However, studies are mixed and could reflect the confounding effects of medication and symptom heterogeneity. Therefore, we considered whether two risk phenotypes, positive schizotypy and hallucinatory predisposition, present in the general population were associated with differential responding profiles for a semantic processing task. One hundred and eighty-three participants completed the Schizotypal Personality Questionnaire, Launay-Slade Hallucination Scale, National Adult Reading Test, a handedness measure, and a computerized semantic relatedness judgment task. Pairs of words were related through their dominant or subordinate meanings, or unrelated. Participants were divided into four groups using a mean split on cognitive-perceptual (positive) schizotypy and hallucination proneness. Significant positive schizotypy and semantic processing.Various external stressors and environmental challenges lead to the provocation of the immune system in autoimmune diseases like Rheumatoid arthritis (RA). The inappropriate immune response further triggers the cascade of inflammatory changes resulting in precipitation of symptoms and hampers quality of life (QOL). The underlying psycho-somatic component of the disease requires a holistic approach to its treatment dimension rather than the use of pharmacotherapy. The applicability of mind-body interventions has become essential in today's fast-paced life. Yoga, a mind-body technique, alters the mind's capacity to facilitate systemic functioning at multiple organ system levels. Hence, we conducted this study to evaluate the impact of 8 weeks of a yoga-based lifestyle intervention (YBLI) on psycho-neuro-immune markers, gene expression patterns, and QOL in RA patients on routine medical therapy. A total of 66 patients were randomized into two groups yoga group or non-yoga group and were assessed for a panel of its as an adjunctive therapy.Given the importance of environmental values (altruistic, biospheric, and egoistic) to pro-environmental behavior, it would be useful to segment the population - an approach known as market segmentation - to tailor pro-environmental messages more effectively. Sociodemographic variables are popular targets for segmentation, as such variables are often knowable in the absence of more nuanced information about individuals. However, evidence for the relationship between sociodemographics and environmental values is sparse, and contradictory. We examined the extent to which popular sociodemographic variables (gender, age, income, education, urbanization level, and political orientation) were predictive of environmental values for 11,820 participants across seven European countries. Overall, sociodemographics were hardly related to environmental values. Only gender and political orientation were weakly but significantly related to environmental values, whereby men and right-wingers showed weaker altruistic and biospheric, and stronger egoistic, values than women and left-wingers. We conclude that sociodemographic variables cannot be considered a suitable proxy for environmental values, and thus that behavior-change campaigns might be more impactful when focused on alternative segmentation strategies in relation to environmental aims.This study aimed to examine bright- and dark-side personality, personal beliefs (religion and politics) and self-evaluation correlates of beliefs in the Militant Extremist Mindset (MEM). In all, 506 young adults completed various self-report measures in addition to the three-dimensional MEM questionnaire. The measures included short measures of the Big Five traits, Self-Monitoring, Self-Evaluation and Personality Disorders, as well as demographic questions of how religious and politically liberal participants were. The Proviolence, Vile World, and Divine power mindsets showed varying correlates, with no consistent trend. Stepwise regressions showed that the demographic, personality and belief factors accounted for between 14% (Vile World) and 54% (Divine Power) of the variance, There were many differences between the results of three mindset factors, but personality disorder scores remained positive predictors of all three. The Vile World mindset was predicted by religiousness, liberalism, personality disorder scores and negative self-monitoring, but not personality traits. Religiousness had a contribution to all subscales and predicted the vast majority of the Divine Power mindset with smaller relationships with personality and personality disorders. Proviolence was predicted by the majority personality measures and sex.Residents' wellbeing in the present COVID-19 global health crisis requires a deeper understanding to determine appropriate management strategies to promote sustainable behaviors and contribute to human and planetary health. Residents' behavior can have a profound influence in contributing to personal and global community's health by responding effectively to emergency strategies in disease outbreaks such as the Coronavirus. It is evident that an understanding of residents' behavior(s) pre COVID-19 across fields have relied on over-simplistic models, many of which will need to be revisited. Our interaction with people and nature while respecting social distancing has profound positive impacts on our physical, mental, emotional, and spiritual wellbeing. The current health pandemic has called that people be confined in their homes across many nations as a means to control the spread of the virus and save lives. This calls for research exploring the mechanisms; this paper develops and proposes a conceptual framewe to a sense of attachment and belongingness, trust and overall life satisfaction. Engaging people in low-effort pro-environmental behavior to maintain some levels of physical activity and biological harmony with natural environmental settings (e.g., gardening) may help reduce anxiety and distress. This is the first study exploring the interplay of relationships between place confinement, pro-social behavior, household pro-environmental behaviors, place attachment as a multi-dimensional construct and presenting their relationships to residents' wellbeing. Behavioral change interventions are proposed to promote lifestyle change for people's wellbeing and broader societal benefits.The precondition of the measurement of longitudinal learning is a high-quality instrument for longitudinal learning diagnosis. This study developed an instrument for longitudinal learning diagnosis of rational number operations. In order to provide a reference for practitioners to develop the instrument for longitudinal learning diagnosis, the development process was presented step by step. The development process contains three main phases, the Q-matrix construction and item development, the preliminary/pilot test for item quality monitoring, and the formal test for test quality control. The results of this study indicate that (a) both the overall quality of the tests and the quality of each item are good enough and that (b) the three tests meet the requirements of parallel tests, which can be used as an instrument for longitudinal learning diagnosis to track students' learning.Ingratiation is regarded as a powerful impression tactic that helps ingratiator achieve their intended goals. Although there is evidence that the consequences of ingratiation are not always positive, little research considers the dark effect of ingratiation on the ingratiator. Based on conservation of resources theory, we develop and test a model that links employees' ingratiation to their counterproductive work behaviors. Data were collected from 216 supervisor-employee dyads. The results of examination with Mplus showed that ingratiation had a positive effect on counterproductive work behaviors, and emotional exhaustion played a mediating role in this relationship. Power distance orientation negatively moderated the relationship between ingratiation and emotional exhaustion and the indirect effect of emotional exhaustion on the relationship between ingratiation and counterproductive work behaviors. Our findings raise attention on the consequences of ingratiation for employees and the dark side of ingratiation for organization.The Iowa gambling task (IGT) is an instrument for the neuropsychological evaluation of cognitive and emotional decision making (DM) processes that was created to test the somatic marker hypothesis (SMH) described by Damasio in 1994. It was initially applied to patients with frontal lobe lesions due to its association with executive functions but was subsequently used on patients with a variety of disorders. https://www.selleckchem.com/products/blu9931.html Although the DM process is inherently perceptual, few studies have applied the IGT to examine DM processes in patients with eating disorders (EDs), and even fewer have associated the IGT to the perceptual distortion of body image (PDBI) in this population. People diagnosed with ED exhibit heightened control over their somatic responses-for example, they can delay digestion for hours-and DM may be affected in this condition. This study compares the performance of two samples of adolescent women-hospitalized patients with ED, and healthy controls with similar demographic characteristics-on the IGT using body image as a possible factor in the SMH.

10/02/2024


This research contributes to the literature gap of investors' psychological behavior during a pandemic outbreak. The study suggests that policy-makers should design a plan to fight against COVID-19. The government should manage the health sector's budget to overcome future crises.This study identified and compared the attitudes of visitors toward zoo-housed little penguins, their enclosure and visitor experience that may influence the way visitors behave toward little penguins at two Australian zoos. Visitor attitudes were assessed using an anonymous questionnaire, targeting visitor beliefs, and experiences, where visitors were randomly approached at the penguin exhibit after they had finished viewing the penguins. Visitors were given two options to complete the questionnaire, on an iPad during their zoo visit or online (URL sent via email) after their zoo visit. A total of 638 participants (495 at Melbourne Zoo and 143 at Taronga Zoo) completed the questionnaire, 42% were completed onsite during their zoo visit and 58% were completed online after their zoo visit. Most participants were living in Australia, non-zoo members, female, previously or currently owned a pet, aged between 26 and 35 years and had a University degree. Results showed that the attitude dimensions of visitors werenclosure and visitor experience at the enclosure; more positive visitor attitudes were associated with higher ratings of penguin welfare, the enclosure and visitor experience. The practical implications of these results for zoos is unclear because the differences in visitor attitudes were numerically small. This requires further comparisons between zoos or enclosures that are more markedly different than the penguin enclosures in the present study and further research on how visitors assess zoo animals, enclosures and visitor experience.The aims of this study were to analyze the peak physical demands in elite futsal by quantifying the most demanding scenarios of match play and to identify the differences between playing positions (defenders, wingers, and pivots) and the seasonal trend for five different rolling average time windows (30, 60, 120, 180, and 300 s). The most demanding scenarios of external load from distance, speed, acceleration, and deceleration variables were obtained from 14 elite futsal players using a local positioning system during 15 official matches in the premier Spanish Futsal League (2018-2019 season). The results showed an extremely large effect of the time window for all dependent variables in all positional groups. Another important finding of this study was that, in regard to the seasonal trend, only defenders reported clear moderate-large positive trends for high-speed running (>18 km⋅h-1) efforts, high-acceleration efforts, and high-deceleration efforts. Finally, moderate-large individual differences in player means for all dependent variables and clear differences between games for most dependent variables were found, suggesting how likely contextual factors may exert an influence on how "demanding" the most demanding scenarios are. The findings of this study provide coaches and strength and conditioning coaches further knowledge of the peak physical demands in elite futsal competition. This valuable information may lead to a more precise position-specific training prescription.Perfectionism has been studied for almost 30 years. In the present study, we investigated the internal validity of The Perfectionism Inventory (PI-Hill et al., 2004) in an occupation that encourages perfectionistic tendencies in own behavior or in students' behavior. We collected data from a large sample of schoolteachers (N = 633, 81.18% female, 63.02% from urban areas, 46.66% from secondary schools, mean age = 42.11 years) recruited using a snowball sampling approach, and we analyzed the factor structure of the PI using confirmatory factor analyses. We found that the 8-factor structure of PI provided a reasonable fit root mean square error of approximation [RMSEA = 0.055, 90% CI = (0.053-0.057); SRMR = 0.071]. However, additional analyses revealed problematic divergent validity only in the case of the scales associated with self-evaluative perfectionism, not in the case of the scales associated with conscientious perfectionism. We found that teachers displayed distinguishably different forms of perfectionism only when it referred to own person, not when it referred to perfectionism imposed to others. Based on these findings, we suggested that the PI could provide a useful framework for investigating the role of conscientious-related forms of perfectionism in the development of teacher beliefs regarding their school behavior.In the digital world of today, multitasking with media is inevitable. Research shows, for instance, that American youths spend on average 7.5 h every day with media, and 29% of that time is spent processing different forms of media simultaneously (Uncapher et al., 2017). Despite numerous studies, however, there is no consensus on whether media multitasking is effective or not. In the current paper, we review existing literature and propose that in order to ascertain whether media multitasking is effective, it is important to determine (1) which goal/s are used as a reference point (e.g., acquiring new knowledge, obtaining the highest number of points in a task, being active on social media); (2) whether a person's intentions and subjective feelings or objective performance are considered (e.g., simultaneous media use might feel productive, yet objective performance might deteriorate); and finally (3) whether the short- or long-term consequences of media multitasking are considered (e.g., media multitasking might help attain one's present goals yet be conducive to a cognitive strategy that leads to lesser attentional shielding of goals). Depending on these differentiations, media multitasking can be seen as both a strategic behavior undertaken to accomplish one's goals and as a self-regulatory failure. The article integrates various findings from the areas of cognitive psychology, psychology of motivation, and human-computer interaction.If our choices make us who we are, then what does that mean when these choices are made in the human-machine interface? Developing a clear understanding of how human decision making is influenced by automated systems in the environment is critical because, as human-machine interfaces and assistive robotics become even more ubiquitous in everyday life, many daily decisions will be an emergent result of the interactions between the human and the machine - not stemming solely from the human. For example, choices can be influenced by the relative locations and motor costs of the response options, as well as by the timing of the response prompts. In drift diffusion model simulations of response-prompt timing manipulations, we find that it is only relatively equibiased choices that will be successfully influenced by this kind of perturbation. However, with drift diffusion model simulations of motor cost manipulations, we find that even relatively biased choices can still show some influence of the perturbation. We report the results of a two-alternative forced-choice experiment with a computer mouse modified to have a subtle velocity bias in a pre-determined direction for each trial, inducing an increased motor cost to move the cursor away from the pre-designated target direction. With queries that have each been normed in advance to be equibiased in people's preferences, the participant will often begin their mouse movement before their cognitive choice has been finalized, and the directional bias in the mouse velocity exerts a small but significant influence on their final choice. With queries that are not equibiased, a similar influence is observed. By exploring the synergies that are developed between humans and machines and tracking their temporal dynamics, this work aims to provide insight into our evolving decisions.Involvement in sport and exercise not only provides participants with health benefits but can be an important aspect of living a meaningful life. The COVID-19 pandemic and the temporary cessation of public life in March/April/May 2020 came with restrictions, which probably also made it difficult, if not impossible, to participate in certain types of sport or exercise. Following the philosophical position that different types of sport and exercise offer different ways of "relating to the world," this study explored (dis)continuity in the type of sport and exercise people practiced during the pandemic-related lockdown, and possible effects on mood. Data from a survey of 601 adult exercisers, collected shortly after the COVID-19 outbreak in Finland, were analyzed. Approximately one third (35%) of the participants changed their "worldmaking" and shifted to "I-Nature"-type activities. We observed worse mood during the pandemic in those who shifted from "I-Me," compared to those who had preferred the "I-Nature" relation already before the pandemic and thus experienced continuity. The clouded mood of those experiencing discontinuity may be the result of a temporary loss of "feeling at home" in their new exercise life-world. However, further empirical investigation must follow, because the observed effect sizes were small.The present study aims to identify contextual and psychological factors of proneness to radicalization and violent extremism (RVE) operationalized through the Militant Extremist Mindset scale (MEM) consisting of three distinct aspects Proviolence (PV), Vile World beliefs (VW), and trust in Divine Power (DP). A community sample of 271 high school students (72% females) from Belgrade and Sandžak regions in Serbia completed (1) a 24-item MEM scale; (2) contextual measures including a 6-item scale of family dysfunction (FDys) and a 4-item composite measure capturing exposure to a harsh school environment and peer abuse (HSE); (3) psychological measures including the 9-item Right-Wing Authoritarianism scale (RWA), the 5-item Social Dominance Orientation scale (SDO), and the 20-item UCLA Loneliness scale (LON). A path analysis was conducted with contextual factors on the first and psychological factors on the second level of the model predicting the three factors of MEM. LON was positively predicted by FDys and HSE, SDO by HSE only, while RWA was positively predicted by FDys only. https://www.selleckchem.com/products/otssp167.html Contextual and psychological factors accounted for 27% of the variance in PV (LON, SDO), 15% of the variance in VW (FDys, SDO), and 31% of the variance in DP (RWA). Obtained findings reveal a complex interplay of contextual and psychological drivers in the prediction of different aspects of RVE and build upon existing knowledge on risk factors associated with RVE.Physical Education (PE) aims to convey the joy of exercise and by this educate students to lifelong physical activeness. Student motivation in PE decreases during the school career. This study therefore comprehensively analyzes student characteristics determining motivation in PE General Personality Traits, Physical Self-Concept, Achievement Motive, Motives to be physically active, and Sports Interest. This contribution aims to describe students' prerequisites in the PE context by using an aggregated assessment of the abovementioned general plus sport specific characteristics and to detect gender, class, and school type differences. In total, 1,740 German secondary school students (58.1% female, M = 14.39 years) participate in a cross-sectional questionnaire survey. Descriptive analyses and between subjects MANOVAs followed by univariate ANOVAs with pairwise multiple comparison tests are applied. Gender explains the largest proportion of variance across all characteristics. Regarding individual dimensions, genders differed on 12, grades on two and school types on 11 out of 19 dimensions.