Posts

5 hrs ago


The study aims to examine the effects of coronavirus disease-2019 (COVID-19) measures on global environment and fertility rate by using the data of 1980 to 2019. The results show that communicable diseases including COVID-19 measures decrease carbon emissions and increase the chances of fertility rates in an account of city-wide lockdown. The knowledge spillover substantially decreases carbon emissions, while high energy demand increases carbon emissions. Poverty incidence increases fertility rate in the short-run; however, in the long-run, the result only supported with vulnerable employment and food prices that lead to increase fertility rates worldwide. The study concludes that besides some high negative externalities associated with COVID-19 pandemic in the form of increasing death tolls and rising healthcare costs, the global world should have to know how to direct high mass carbon emissions and population growth through acceptance of preventive measures, which would be helpful to contain coronavirus pandemic at a global scale.First time in India, total lockdown was announced on 22 March 2020 to stop the spread of COVID-19 and the lockdown was extended for 21 days on 24 March 2020 in the first phase. During the total lockdown, most of the sources for poor air quality were stopped in India. In this paper, we present an analysis of air quality (particulate matter-PM2.5, Air Quality Index, and tropospheric NO2) over India using ground and satellite observations. A pronounced decline in PM2.5 and AQI (Air Quality Index) is observed over Delhi, Mumbai, Hyderabad, Kolkata, and Chennai and also a declining trend was observed in tropospheric NO2 concentration during the lockdown period in 2020 compared with the same period in the year 2019. During the total lockdown period, the air quality has improved significantly which provides an important information to the cities' administration to develop rules and regulations on how they can improve air quality.Many governments around the world have enforced quarantine policies to control the spread of the new coronavirus (SARS-CoV-2). These policies have had positive and negative effects on the environment. For example, the concentrations of certain harmful pollutants have decreased in some countries. In contrast, the concentrations of other pollutants have increased. This research analyzes the effect of quarantine policies on air quality in Quito, Ecuador. Using a parametric approach, it was found that NO2 and PM2.5 concentrations have decreased significantly since the establishment of lockdown measures. However, O3 concentrations have increased considerably in 2020.Air pollution (AP) is one of the major causes of health risks as it leads to widespread morbidity and mortality each year. Its environmental impacts include acid rains, reduced visibility, but more importantly and significantly, it affects human health. The price tag of not managing AP is seen in the rise of chronic obstructive pulmonary disease (COPD), cardiovascular disease, and respiratory ailments like asthma and chronic bronchitis. But as the world battles the corona pandemic, COVID-19 lockdown has abruptly halted human activity, leading to a significant reduction in AP levels. The effect of this reduction is captured by reduced cases of morbidity and mortality associated with air pollution. The current study aims to monetarily quantify the decline in health impacts due to reduced AP levels under lockdown scenario, as against business as usual, for four cities-Delhi, London, Paris, and Wuhan. The exposure assessment with respect to pollutants like particulate matter (PM2.5 and PM10), NO2, and SO2 are evaluated. Value of statistical life (VSL), cost of illness (CoI), and per capita income (PCI) for disability-adjusted life years (DALY) are used to monetize the health impacts for the year 2019 and 2020, considering the respective period of COVID-19 lockdown of four cities. The preventive benefits related to reduced AP due to lockdown is evaluated in comparison to economic damage sustained by these four cities. This helps in understanding the magnitude of actual damage and brings out a more holistic picture of the damages related to lockdown.The worldwide outbreak of COVID-19 disease has caused immense damage to our health and economic and social life. This research article helps to determine the impact of climate on the lethality of this disease. Air quality index and average humidity are selected from the family of climate variables, to determine its impact on the daily new cases of COVID-19-related deaths in Wuhan, China. We have used wavelet analysis (wavelet transform coherence (WTC), partial (PWC), and multiple wavelet coherence (MWC), due to its advantages over traditional time series methods, to study the co-movement nexus between our selected data series. Findings suggest a notable coherence between air quality index, humidity, and mortality in Wuhan during a recent outbreak. Humidity is negatively related to the COVID-19-related deaths, and bad air quality leads to an increase in this mortality. These findings are important for policymakers to save precious human lives by better understanding the interaction of the environment with the COVID-19 disease.Coronavirus diseases 2019 (COVID-19) is transmitted worldwide in over a very short time, as it was originated in late 2019 from Wuhan city, China. To reduce the possible effects due to COVID-19, some sort of lockdown activities have been applied in many countries. https://www.selleckchem.com/products/defactinib.html In this regard, the outcomes reported bonus benefits to the natural environment showing a significant decrease in air pollution worldwide due to COVID-19. The National Aeronautics and Space Administration (NASA) and European Space Agency (ESA) released air pollution data for Asian and European countries to assess the significant changes in air quality. The main objective of the study is to compare the air quality data released by international agencies before and after the novel coronavirus pandemic.Drug delivery through the skin by transdermal patches has a long history. Subsequent growth of transdermal science proved prominent utility of transdermal systems meant for passive diffusion of the drug. It was followed by the development of iontophoresis- and sonophoresis-based transdermal delivery systems. Microneedle array has now caught attention of the investigators owing to its immense utility in transdermal delivery of very large molecules with ionic and hydrophilic nature. In this technical note, we present the current scenario, applications, and recent advances in microneedle array-based delivery of the most critical molecules through the skin. The application of microneedle has widely been investigated, and these technologies are being developed for the delivery of bio-therapeutics, bio-macromolecules, insulin, growth hormones, immunobiologicals, proteins, siRNA, and peptides. Potential of microneedles to transform the global transdermal market is highlighted in terms of the success rate of the microneedle technologies in clinical trials reaching to the global market.

6 hrs ago


Obesity in the United States is increasingly prevalent in adolescents. Metabolic and bariatric surgery is offered at select sites to adolescents (<18 yr). Controversy exists regarding the safety of performing metabolic and bariatric surgery in adolescents.

The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program registry was employed to compare outcomes of adolescents with adults (18-40 yr) undergoing sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).

Academic Teaching Institution.

The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Participant User Files were reviewed for patients undergoing SG or RYGB (2015-2018). Patients were stratified by age and outcomes for adolescents versus adults compared. A bivariate analysis was performed on propensity-matched data.

After exclusion criteria were applied, 227,671 patients <40 years remained, of whom 1005 were adolescents. https://www.selleckchem.com/products/atglistatin.html For those undergoing RYGB (13.8% adolescents, 25.3% adults), demohan RYGB, and adolescent SG patients have similar outcomes and shorter operating room times compared with adolescent RYGB patients.The general boundaries to tooth movement are within the adjacent compact and trabecular bones, gingiva, mucosa, and muscular envelope. Findings from finite element analysis of maxillary posterior teeth distalization against mini-implants suggest that stiff outer and interproximal compact bone resists tooth movement, regardless of bone thickness, and that teeth should be steered away from this bone during orthodontic treatment. However, individual variation in the tooth-bone interface dictates the course and outcome of treatment, offering the basis for inferences on the limits of mini-implant anchorage and the presumed influence of the regional acceleratory phenomenon through decortication and microperforation, 2 modalities advocated to effect faster tooth movement.
Nasoalveolar molding (NAM) was introduced over 20years ago as adjunctive therapy for the correction of cleft lip and palate. In the current study, we propose a new approach using a digital workflow and 3-dimensional printing to fabricate clear aligner NAM devices.

A polyvinyl siloxane (PVS)impression of an infant with a unilateral complete cleft lip and palate (UCLP) is acquired and poured, and the stone model is scanned with an intraoral scanner. The stereolithography file is digitized, and the alveolar segments are digitally segmented and moved to the desired final position. The total distance moved is divided into a sequence of 1-1.5mm increments, creating a series of digital models. The models are 3-dimensionally printed along with button templates to allow free form positioning of the button on each model. A Vacuformmachine (Taglus, Mumbai, India) was used to fabricate a 0.040-in aligner for each stage.

We present 1 case that was treated successfully with this approach. Appointments for the NAM adjustments were primarily to monitor progress and counseling with less time spent adjusting the appliance. The appointment length was reduced by over 30minutes. Benefits of the aligner are improved fit, more precise increments of activation, reduced chairside time, and potentially minimized number of visits.

NAM custom aligners may provide similar benefits to the traditional approach while reducing the burden of care by reducing the number of visits and appointment duration. Further studies with a sample and longitudinal observations are needed to investigate the benefits of the proposed digital approach.
NAM custom aligners may provide similar benefits to the traditional approach while reducing the burden of care by reducing the number of visits and appointment duration. Further studies with a sample and longitudinal observations are needed to investigate the benefits of the proposed digital approach.
A growing number of adult patients are seeking orthodontic treatment. This research aimed to analyze the particulars of patients seeking retreatment and identify the causes of their original treatment failure.

An online questionnaire survey of adults seeking first-time orthodontic treatment (control) and retreatment (study) was conducted. Index of complexity, outcome, and need (ICON) scores were determined. Appraisal of treatment records was carried out to identify the causes of original treatment failure.

No significant differences were found between retreatment adult patients and first-timers regarding reasons for seeking orthodontic treatment, malocclusion type, self-perception of malocclusion, level of self-motivation, willingness for surgery, expectations of treatment improvement and duration. The predominant reason for seeking treatment in both groups was for aesthetic concerns. Retreatment patients presented with lower ICON scores (39.4; standard error, 0.26) than the first-time patients (54.3; sding reasons patients sought treatment. ICON was not a useful proxy of patient profiles. Poor treatment was the chief reason for the failure of the original treatment. In terms of clinical significance, clinicians should be mindful of the patient profiles of retreatment seekers and vigilant about the possible causes of failings of orthodontic treatment to avoid suboptimal outcomes.
This retrospective study aimed to assess the stability of Class II malocclusion treatment with the distal jet, followed by fixed appliances.

Seventy-five cephalograms of 30 subjects were divided into 2 groups. The treated group consisted of 15 patients who were evaluated at the pretreatment, posttreatment, and long-term posttreatment stages. The control group consisted of 15 subjects with normal occlusion, comparable to the experimental group at the long-term posttreatment period. Intergroup comparison of posttreatment changes was evaluated with t tests.

In the long-term posttreatment period, there was no significant change in the anteroposterior position of the maxilla and mandible to the cranial base. The lower anterior face height had a significantly smaller increase in the treated than in the control group. The maxillary molars in the treated group had significantly smaller vertical development, and the mandibular incisors had significantly greater labial tipping and protrusion than the control group.

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Discover the hidden gems of Bhutan with our Bhutan Tour Package from Mumbai. From the iconic Tiger’s Nest Monastery to the peaceful valleys and vibrant festivals, our expertly designed itinerary promises an enriching experience. Travel comfortably from Mumbai and immerse yourself in Bhutan's unique charm. Visit now https://www.denzongleisure.com/

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Posts

5 hrs ago


The study aims to examine the effects of coronavirus disease-2019 (COVID-19) measures on global environment and fertility rate by using the data of 1980 to 2019. The results show that communicable diseases including COVID-19 measures decrease carbon emissions and increase the chances of fertility rates in an account of city-wide lockdown. The knowledge spillover substantially decreases carbon emissions, while high energy demand increases carbon emissions. Poverty incidence increases fertility rate in the short-run; however, in the long-run, the result only supported with vulnerable employment and food prices that lead to increase fertility rates worldwide. The study concludes that besides some high negative externalities associated with COVID-19 pandemic in the form of increasing death tolls and rising healthcare costs, the global world should have to know how to direct high mass carbon emissions and population growth through acceptance of preventive measures, which would be helpful to contain coronavirus pandemic at a global scale.First time in India, total lockdown was announced on 22 March 2020 to stop the spread of COVID-19 and the lockdown was extended for 21 days on 24 March 2020 in the first phase. During the total lockdown, most of the sources for poor air quality were stopped in India. In this paper, we present an analysis of air quality (particulate matter-PM2.5, Air Quality Index, and tropospheric NO2) over India using ground and satellite observations. A pronounced decline in PM2.5 and AQI (Air Quality Index) is observed over Delhi, Mumbai, Hyderabad, Kolkata, and Chennai and also a declining trend was observed in tropospheric NO2 concentration during the lockdown period in 2020 compared with the same period in the year 2019. During the total lockdown period, the air quality has improved significantly which provides an important information to the cities' administration to develop rules and regulations on how they can improve air quality.Many governments around the world have enforced quarantine policies to control the spread of the new coronavirus (SARS-CoV-2). These policies have had positive and negative effects on the environment. For example, the concentrations of certain harmful pollutants have decreased in some countries. In contrast, the concentrations of other pollutants have increased. This research analyzes the effect of quarantine policies on air quality in Quito, Ecuador. Using a parametric approach, it was found that NO2 and PM2.5 concentrations have decreased significantly since the establishment of lockdown measures. However, O3 concentrations have increased considerably in 2020.Air pollution (AP) is one of the major causes of health risks as it leads to widespread morbidity and mortality each year. Its environmental impacts include acid rains, reduced visibility, but more importantly and significantly, it affects human health. The price tag of not managing AP is seen in the rise of chronic obstructive pulmonary disease (COPD), cardiovascular disease, and respiratory ailments like asthma and chronic bronchitis. But as the world battles the corona pandemic, COVID-19 lockdown has abruptly halted human activity, leading to a significant reduction in AP levels. The effect of this reduction is captured by reduced cases of morbidity and mortality associated with air pollution. The current study aims to monetarily quantify the decline in health impacts due to reduced AP levels under lockdown scenario, as against business as usual, for four cities-Delhi, London, Paris, and Wuhan. The exposure assessment with respect to pollutants like particulate matter (PM2.5 and PM10), NO2, and SO2 are evaluated. Value of statistical life (VSL), cost of illness (CoI), and per capita income (PCI) for disability-adjusted life years (DALY) are used to monetize the health impacts for the year 2019 and 2020, considering the respective period of COVID-19 lockdown of four cities. The preventive benefits related to reduced AP due to lockdown is evaluated in comparison to economic damage sustained by these four cities. This helps in understanding the magnitude of actual damage and brings out a more holistic picture of the damages related to lockdown.The worldwide outbreak of COVID-19 disease has caused immense damage to our health and economic and social life. This research article helps to determine the impact of climate on the lethality of this disease. Air quality index and average humidity are selected from the family of climate variables, to determine its impact on the daily new cases of COVID-19-related deaths in Wuhan, China. We have used wavelet analysis (wavelet transform coherence (WTC), partial (PWC), and multiple wavelet coherence (MWC), due to its advantages over traditional time series methods, to study the co-movement nexus between our selected data series. Findings suggest a notable coherence between air quality index, humidity, and mortality in Wuhan during a recent outbreak. Humidity is negatively related to the COVID-19-related deaths, and bad air quality leads to an increase in this mortality. These findings are important for policymakers to save precious human lives by better understanding the interaction of the environment with the COVID-19 disease.Coronavirus diseases 2019 (COVID-19) is transmitted worldwide in over a very short time, as it was originated in late 2019 from Wuhan city, China. To reduce the possible effects due to COVID-19, some sort of lockdown activities have been applied in many countries. https://www.selleckchem.com/products/defactinib.html In this regard, the outcomes reported bonus benefits to the natural environment showing a significant decrease in air pollution worldwide due to COVID-19. The National Aeronautics and Space Administration (NASA) and European Space Agency (ESA) released air pollution data for Asian and European countries to assess the significant changes in air quality. The main objective of the study is to compare the air quality data released by international agencies before and after the novel coronavirus pandemic.Drug delivery through the skin by transdermal patches has a long history. Subsequent growth of transdermal science proved prominent utility of transdermal systems meant for passive diffusion of the drug. It was followed by the development of iontophoresis- and sonophoresis-based transdermal delivery systems. Microneedle array has now caught attention of the investigators owing to its immense utility in transdermal delivery of very large molecules with ionic and hydrophilic nature. In this technical note, we present the current scenario, applications, and recent advances in microneedle array-based delivery of the most critical molecules through the skin. The application of microneedle has widely been investigated, and these technologies are being developed for the delivery of bio-therapeutics, bio-macromolecules, insulin, growth hormones, immunobiologicals, proteins, siRNA, and peptides. Potential of microneedles to transform the global transdermal market is highlighted in terms of the success rate of the microneedle technologies in clinical trials reaching to the global market.

6 hrs ago


Obesity in the United States is increasingly prevalent in adolescents. Metabolic and bariatric surgery is offered at select sites to adolescents (<18 yr). Controversy exists regarding the safety of performing metabolic and bariatric surgery in adolescents.

The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program registry was employed to compare outcomes of adolescents with adults (18-40 yr) undergoing sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).

Academic Teaching Institution.

The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Participant User Files were reviewed for patients undergoing SG or RYGB (2015-2018). Patients were stratified by age and outcomes for adolescents versus adults compared. A bivariate analysis was performed on propensity-matched data.

After exclusion criteria were applied, 227,671 patients <40 years remained, of whom 1005 were adolescents. https://www.selleckchem.com/products/atglistatin.html For those undergoing RYGB (13.8% adolescents, 25.3% adults), demohan RYGB, and adolescent SG patients have similar outcomes and shorter operating room times compared with adolescent RYGB patients.The general boundaries to tooth movement are within the adjacent compact and trabecular bones, gingiva, mucosa, and muscular envelope. Findings from finite element analysis of maxillary posterior teeth distalization against mini-implants suggest that stiff outer and interproximal compact bone resists tooth movement, regardless of bone thickness, and that teeth should be steered away from this bone during orthodontic treatment. However, individual variation in the tooth-bone interface dictates the course and outcome of treatment, offering the basis for inferences on the limits of mini-implant anchorage and the presumed influence of the regional acceleratory phenomenon through decortication and microperforation, 2 modalities advocated to effect faster tooth movement.
Nasoalveolar molding (NAM) was introduced over 20years ago as adjunctive therapy for the correction of cleft lip and palate. In the current study, we propose a new approach using a digital workflow and 3-dimensional printing to fabricate clear aligner NAM devices.

A polyvinyl siloxane (PVS)impression of an infant with a unilateral complete cleft lip and palate (UCLP) is acquired and poured, and the stone model is scanned with an intraoral scanner. The stereolithography file is digitized, and the alveolar segments are digitally segmented and moved to the desired final position. The total distance moved is divided into a sequence of 1-1.5mm increments, creating a series of digital models. The models are 3-dimensionally printed along with button templates to allow free form positioning of the button on each model. A Vacuformmachine (Taglus, Mumbai, India) was used to fabricate a 0.040-in aligner for each stage.

We present 1 case that was treated successfully with this approach. Appointments for the NAM adjustments were primarily to monitor progress and counseling with less time spent adjusting the appliance. The appointment length was reduced by over 30minutes. Benefits of the aligner are improved fit, more precise increments of activation, reduced chairside time, and potentially minimized number of visits.

NAM custom aligners may provide similar benefits to the traditional approach while reducing the burden of care by reducing the number of visits and appointment duration. Further studies with a sample and longitudinal observations are needed to investigate the benefits of the proposed digital approach.
NAM custom aligners may provide similar benefits to the traditional approach while reducing the burden of care by reducing the number of visits and appointment duration. Further studies with a sample and longitudinal observations are needed to investigate the benefits of the proposed digital approach.
A growing number of adult patients are seeking orthodontic treatment. This research aimed to analyze the particulars of patients seeking retreatment and identify the causes of their original treatment failure.

An online questionnaire survey of adults seeking first-time orthodontic treatment (control) and retreatment (study) was conducted. Index of complexity, outcome, and need (ICON) scores were determined. Appraisal of treatment records was carried out to identify the causes of original treatment failure.

No significant differences were found between retreatment adult patients and first-timers regarding reasons for seeking orthodontic treatment, malocclusion type, self-perception of malocclusion, level of self-motivation, willingness for surgery, expectations of treatment improvement and duration. The predominant reason for seeking treatment in both groups was for aesthetic concerns. Retreatment patients presented with lower ICON scores (39.4; standard error, 0.26) than the first-time patients (54.3; sding reasons patients sought treatment. ICON was not a useful proxy of patient profiles. Poor treatment was the chief reason for the failure of the original treatment. In terms of clinical significance, clinicians should be mindful of the patient profiles of retreatment seekers and vigilant about the possible causes of failings of orthodontic treatment to avoid suboptimal outcomes.
This retrospective study aimed to assess the stability of Class II malocclusion treatment with the distal jet, followed by fixed appliances.

Seventy-five cephalograms of 30 subjects were divided into 2 groups. The treated group consisted of 15 patients who were evaluated at the pretreatment, posttreatment, and long-term posttreatment stages. The control group consisted of 15 subjects with normal occlusion, comparable to the experimental group at the long-term posttreatment period. Intergroup comparison of posttreatment changes was evaluated with t tests.

In the long-term posttreatment period, there was no significant change in the anteroposterior position of the maxilla and mandible to the cranial base. The lower anterior face height had a significantly smaller increase in the treated than in the control group. The maxillary molars in the treated group had significantly smaller vertical development, and the mandibular incisors had significantly greater labial tipping and protrusion than the control group.

Unforgettable Bhutan Tour Package from Mumbai – Explore the Land of Happiness

Discover the hidden gems of Bhutan with our Bhutan Tour Package from Mumbai. From the iconic Tiger’s Nest Monastery to the peaceful valleys and vibrant festivals, our expertly designed itinerary promises an enriching experience. Travel comfortably from Mumbai and immerse yourself in Bhutan's unique charm. Visit now https://www.denzongleisure.com/

Incredible Bhutan Tour Package from Mumbai – Your Gateway to the Himalayas

Experience the magic of Bhutan with our exclusive Bhutan Tour Package from Mumbai. Offering a perfect blend of adventure, culture, and natural beauty, our package is designed to give you an unforgettable journey. Travel comfortably from Mumbai and explore Bhutan’s stunning landscapes, monasteries, and vibrant traditions. Book your Bhutan adventure today and create lasting memories on this incredible Himalayan escape! Visit now https://www.denzongleisure.com/

12 hrs ago

মুম্বাইয়ের নানাবতী হাসপাতালের একজন শীর্ষস্থানীয় কার্ডিওভাসকুলার সার্জন ডাঃ হেমন্ত পাঠারে, উন্নত হার্ট এবং ভাস্কুলার সার্জারিতে বিশেষজ্ঞ। তিনি ব্যাপক দক্ষতার সাথে জটিল হার্টের অবস্থার জন্য সুনির্দিষ্ট যত্ন প্রদান করেন।

আরও তথ্যের জন্য, আপনি আমাদের সাথে যোগাযোগ করতে পারেন:-
✅ফোন নম্বর:-+91-9370586696
✅ইমেল ঠিকানা:- drhpathare@indiacardiacsurgerysite.com

আমাদের আরও পড়ুন: - https://www.indiacardiacsurgerysite.com/bangla-dr-hemant-pathare-best-cardiovascular-surgeon-mumbai-india.html