OBJECTIVE To explore the various types and phases of clinical trials, the regulatory oversight, drug approval process, and implications of clinical trials for the oncology nurse. DATA SOURCES Peer-reviewed journal articles, internet, book chapters, white papers. CONCLUSION Oncology nurses' interactions with patients entered on clinical trial and communication with the clinical research team is crucial to the successful conduct of clinical trials. The oncology nurse must work in concert with the clinical research team to protect patient safety and to produce accurate information for protocol requirements that will be used to evaluate whether a drug becomes approved or not by the US Food and Drug Administration. IMPLICATIONS FOR NURSING PRACTICE Oncology nurses play a central role to the successful outcome of clinical research studies. Nurses must work in close collaboration with the clinical research teams for the successful completion and adherence of the clinical trial and to maintain the safety of the patient enrolled into clinical trial. OBJECTIVES This article will provide an overview of the purpose, structure, and function of an investigational pharmacy in oncology clinical research. It will also discuss the role of the oncology nurse in managing investigational drugs (ID) when caring for a patient receiving treatment on a clinical trial and the importance of their role in the trial process. DATA SOURCES Government regulations, professional guidelines, and best practices. CONCLUSION ID management for clinical trials is a multidisciplinary process requiring input from various professionals to ensure safe, accurate, and study-specific administration. The nurse's role in the process of clinical trial ID management is dependent on each institution's expectations of clinical research nurses and the scope of their role. IMPLICATIONS FOR NURSING PRACTICE Multiple nursing roles may be involved in caring for patients who are being treated as part of a clinical trial, including clinical research nurses, infusion nurses, or as nurses providing direct patient care (inpatient or outpatient). Providing education on ID management, specific to the nurse's involvement, is a responsibility of the study team. Ensuring proper safeguards, accurate and protocol-specific delivery and documentation of ID, and completion of patient education are key in the conduct of oncology clinical research. OBJECTIVES To explore the federal regulations governing clinical trials and human subject protection, the importance of research participant's informed consent, and the role the oncology clinical research nurse has within the clinical trial setting. DATA SOURCES Peer-reviewed journal articles, internet, book chapters, white papers. CONCLUSION Federal regulations mandate the conduct of a clinical research trial, human research participant protection, and the informed consent process. IMPLICATIONS FOR NURSING PRACTICE The oncology nurse supports the autonomy and safe conduct of the human research participant during a clinical research trial and provides education and support through the informed consent process. OBJECTIVES To describe the evolution and structure of the National Cancer Institute clinical trials programs, their notable accomplishments, nurses' roles in these accomplishments, and the essential role of nursing today and in the future. DATA SOURCES Manuscripts, government publications, websites, and professional communications. CONCLUSION Change is inevitable and a constant factor in the world of advancing science and clinical research. Nurses' contribution to research and evidence-based practice will continue to grow and is vital as the scientific landscape evolves. IMPLICATIONS FOR NURSING PRACTICE As the understanding of cancer biology increases and clinical trials evolve, nurses will need to remain key team members and leaders in National Cancer Institute Community Oncology Research Program and National Cancer Trials Network trials and their associated infrastructure. Published by Elsevier Inc.Increasing emergence and spread of Nipah, ZIKV and Ebola case and potential outbreaks threats have been reported in several regions around the globe. Yet, emerging Nipah, Ebola and Zika viral diseases outbreaks have been indirectly linked to substantially globalization of trade and travel, climate change and intense urbanization impact, healthcare and socioeconomic inequities as well in affected community settings. Although no case has been documented in Saudi Arabia, there is a great risk of sudden emergence of any of these viruses and others via introducing among pilgrims coming from endemic regions during ritual ceremonies of mass gatherings. Consequently, promoting and investing on new and sensitive proven effective and innovative surveillance and monitoring approaches, including enhanced risk communication, improved integrated vectors surveillance in addition to improved sustainable highly pathogens surveillance control programs to human motility and environmental sanitation strategies all represent 'Oneffectiveness is needed through One Health approach integration in attaining pilgrims and local population health safety and security, in advancing Saudi sustainable health development goals. BACKGROUND The usefulness of laboratory tests in the decision-making process with regard to early identification of dengue virus infection has not been widely reported, particularly the aspartate aminotransferase (AST)/platelet count ratio index during a patient's days of illness. The aim of this study was to examine the pattern of the ratio index over the course of illness and identify whether it is a marker of dengue virus infection in dengue patients, as well as to assess the role of other laboratory tests. METHODS A chart review of 205 dengue patients was analyzed using available records of 845 laboratory results within different time intervals or exam dates during the course of illness. We used repeated measures mixed binary logistic regression analyses to model the dengue virus infection, defined as giving at least one positive antibody test (yes/no). RESULTS The high risk of dengue virus infection in dengue patients was found in the male gender (adjusted OR=4.316, 95% CI 1.285-14.498, P=0.018), in patients with a high AST/platelet count ratio index (adjusted OR=1.438, 95% CI 1.057-1.957, P=0.021), in patients with a low MCV level (adjusted OR=0.815, 95% CI 0.679-0.978, P=0.028), and in patients with a low ALT level (adjusted OR=0.996, 95% CI 0.993-0.999, P=0.010). CONCLUSION Laboratory markers, in particular the AST/platelet count ratio index, can be useful for clinicians to strengthen the decision-making process in primary care settings. Furthermore, our model revealed that low MCV and low ALT are predictors of the dengue virus infection, while being a male increases the risk of dengue virus infection. More studies are needed to evaluate the impact of the AST/platelet count ratio index on the severity of dengue fever infection during the onset of symptoms and course of treatment. https://www.selleckchem.com/products/mitapivat.html Stress can induce reproductive deficits by activating the HPA and causing oxidative stress. Some studies have indicated that the neurologic diseases or disorders induced by stress could be relieved by probiotics. Whether chronic unpredictable stress (CUS)-induced reproductive deficits could be prevented by probiotics is unclear. The present experiment was designed to evaluate the effects of L. rhamnosus Gorbach-Goldin (LGG) on CUS-induced reproductive deficits. Kunming mice were divided into control, stress, and LGG groups randomly. The mice in stress and LGG groups were exposed to CUS for 40days, in the meantime, the mice in LGG group were orally administered with LGG suspension at a dose of 0.3 mL/mouse (1×1010 cells/mL), and the mice in control and stress groups were orally administered with volume-equivalent sterile saline once a day. The results showed that the CUS-induced the sperm deficits including the count, motility, morphology, ultrastructure, DNA integrity, and chromatin condensation were protected by oral administration of LGG. In addition, the change of testosterone level induced by CUS was prevented by up-regulating the expressions of StAR and P450scc in the testes. Moreover, LGG could increase the activities of catalase, glutathione peroxidase, and superoxide dismutase significantly, and decrease the levels of oxidative products malondialdehyde and protein carbonyls significantly, as well as the levels of cyclooxygenase 2, interleukin (IL)-1β, IL-6, and tumor necrosis factor-α, to block the CUS-induced inflammatory response and the oxidative stress. The results indicated that the CUS-induced male reproductive deficits could be prevented by oral administration of LGG. V.PURPOSE Radiomics are a set of methods used to leverage medical imaging and extract quantitative features that can characterize a patient's phenotype. All modalities can be used with several different software packages. Specific informatics methods can then be used to create meaningful predictive models. In this review, we will explain the major steps of a radiomics analysis pipeline and then present the studies published in the context of radiation therapy. METHODS A literature review was performed on Medline using the search engine PubMed. The search strategy included the search terms "radiotherapy", "radiation oncology" and "radiomics". The search was conducted in July 2019 and reference lists of selected articles were hand searched for relevance to this review. RESULTS A typical radiomics workflow always includes five steps imaging and segmenting, data curation and preparation, feature extraction, exploration and selection and finally modeling. In radiation oncology, radiomics studies have been published to explore different clinical outcome in lung (n=5), head and neck (n=5), esophageal (n=3), rectal (n=3), pancreatic (n=2) cancer and brain metastases (n=2). The quality of these retrospective studies is heterogeneous and their results have not been translated to the clinic. CONCLUSION Radiomics has a great potential to predict clinical outcome and better personalize treatment. But the field is still young and constantly evolving. Improvement in bias reduction techniques and multicenter studies will hopefully allow more robust and generalizable models. INTRODUCTION It is common practice to prescribe prophylactic antiepileptic drugs (AED) to high-grade glioma (HGG) patients without a history of seizures, yet with limited evidence supporting its use. Ideally, the effectiveness of prophylactic anticonvulsants must outweigh the occurrence of adverse effects and interactions related to AED. The authors conducted a systematic review and metanalysis of longitudinal studies regarding the effectiveness of prophylactic AED in seizure-naïve HGG patients. MATERIALS AND METHODS PubMed/MEDLINE, Cochrane Central Register of Controlled trials, Embase and clinicaltrials.gov databases were systematically searched. Of the initial 1773 studies identified, 15 were finally selected for data extraction and analysis. Heterogeneity among studies, pooled hazard ratios, publication bias and sensitivity analyses were performed separately for a 15-study group (HGG patients within larger series of brain tumors) and a 6-study group (exclusively HGG patients). RESULTS AED prophylaxis did not significantly reduce the incidence of postoperative seizures compared with controls, both in the 15-study group (Mantel-Haenszel random-effects pooled OR 1.

Behind quarterback Matt Ryan, operating again Michael Turner, broad receiver Roddy White and defensive end John Abraham, the Atlanta Falcons are poised to be a title contender again in 2011. https://www.broncosjerseysprostore.com/frank-crum-jersey-c-76.html This yr, the brand new Orleans Saints, Inexperienced Bay Packers and Philadelphia Eagles will take on the Falcons in marquee affairs on the Georgia Dome. The Broncos won 41-20.) The Broncos wore their white jerseys for 1983 residence video games in opposition to the Philadelphia Eagles, Los Angeles Raiders and Cincinnati Bengals, however didn't put on white at dwelling once more for two decades - see subsequent section. When the 2 teams met at INVESCO Discipline at Mile Excessive later that season (Week 11), the NFL allowed the visiting Chargers to choose their uniform color in advance, they usually chose navy blue, forcing the Broncos to put on their white jerseys at house. Who have been the top NFL picks of the day? While these teams are anticipated to spice up, they are not thought to be among the NFL picks that will likely be a fundamental danger. Dan Reeves grew to become the youngest head coach (37) within the NFL when he joined the Broncos in 1981 as vice president and head coach.

The article of the sport is to rope each of the broomstick broncos with a rope. The Tremendous Bowl is Sunday, and so begins the ancient tradition of people who couldn’t care less about football or the teams involved gathering round to observe the large recreation. In addition, during the previous a number of seasons we've got been friends of the Broncos to look at a taping of the Denver Huddle tv show, that includes current Bronco gamers akin to Emmanuel Sanders, CJ Anderson and Bennie Fowler. Many groups had respectable seasons very last yr. https://www.broncosjerseysprostore.com/wil-lutz-jersey-c-30.html These groups sq. off as they attempt to show that they're the very best workforce in the NFL. Tebow led the Broncos to an 8-eight report and garnered the staff's first playoff berth and division title since 2005. The Broncos defeated the Pittsburgh Steelers in the Wild Card round on a memorable 80-yard touchdown pass from Tebow to broad receiver Demaryius Thomas on the primary play of extra time, setting a record for the quickest extra time in NFL historical past. The Dallas Cowboys have been really Super Bowl Champions from the year earlier than as they defeated the Denver Broncos 27-10 in Super Bowl XII.

My infatuation with the group began whereas watching Super Bowl XII in 1978 when the Cowboys defeated the Denver Broncos. Whereas the Cowboys demonstrated a dominant defense within the earlier Super Bowl, this Tremendous Bowl would function two potent offenses. Other exciting NFL plays embody Dexter McCluster who garnered 20 yards with a reverse, while player Jones was able to select up nineteen extra for town Chiefs. M. Schaub and A. Johnson performed fairly nicely for the Houston Texans whereas T. Jones was an NFL high pick for the Kansan City Chiefs. The Denver Broncos appear to be set because the team to beat from the AFC or your entire NFL. The following yr the Broncos beat the Atlanta Falcons in Tremendous Bowl XXXIII winning again to again titles - a feat that is sort of rare within the National Soccer League. By following the official accounts of the Denver Broncos or relevant sports activities networks on these platforms, you possibly can stay up-to-date with their live streams.

New England Patriots, in addition to the next week on the San Diego Chargers. Defense to the rescue (2:39 p.m.): As has been the case since Week 6: Vance Joseph’s crew rises to the occasion when its called upon. “The focus for me is that this week simply trying to be the very best teammate I may be,” Wilson mentioned. When the Broncos performed the 2022 opener at Seattle, where Wilson left partially because of irreconcilable differences with administration, the crowd reaction was mixed. https://www.broncosjerseysprostore.com/riley-moss-jersey-c-37.html As soon as Wilson signed with the Steelers in March, this recreation grew to become one of the league’s more intriguing matchups. Over the next two a long time, the franchise turned probably the most successful groups in pro soccer. The 2 NFL teams have certified for the Tremendous Bowl after defeating all other powerful and competent groups throughout all seasons of the National Football (NFL). https://www.broncosjerseysprostore.com/jaquan-mcmillian-jersey-c-34.html Amongst the NFL picks which are anticipated to soar this yr are the Denver Broncos, Tennessee Titans, Chicago Bears and Washington Redskins. Which High Rated NFL Picks Will Survive? Most of closing yr's leading NFL picks continues to be at the main of this yr's listing.

As esteemed members of the American Football Convention (AFC) West division within the Nationwide Soccer League (NFL), the Broncos have a rich history that features a number of Super Bowl championships and quite a few AFC titles. Jan 12 Jack Schroer, American rock saxophonist (Van Morrison's The Caledonia Soul Orchestra), born in Ohio (d. https://www.broncosjerseysprostore.com/michael-burton-jersey-c-9.html Feb 14 Alan Parker, English director (Bugsy Malone, Midnight Specific), born in London, England (d. Though I was born in Oakland, California, and later in life returned to reside within the Bay Area, I wouldn't be caught lifeless wearing a San Francisco 49ers t-shirt or hat. North cities: Chicago Bears, Minnesota Vikings, Green Bay Packers, Detroit Lions fantasy soccer draft? Quick-forward to 1997 and the Broncos gained the Super Bowl beating the closely favored Inexperienced Bay Packers in Tremendous Bowl XXXII. In the episode, "The Bonfire of the Manatees", Homer picks the Broncos to win the Tremendous Bowl over the Seattle Seahawks. Company representing Particular Olympics, Essential Catch and the American Most cancers Society will announce a pair of the Broncos' Day three picks. There may be one workforce that performs from the American Soccer Convention and one other team from the National Soccer Conference. My sister and I have even joked about at some point visiting Texas Stadium (earlier than its demise) to watch a house game as if we had been sports activities pilgrims on a spiritual journey to our soccer mecca.

Actually, even when you haven't any curiosity in football in anyway, watching Cam Newton do just about anything is a treat. At the moment we lived in Albuquerque, New Mexico, and my household never watched any football games. He’s donated to help households impacted by the coronavirus pandemic, committing $100,000 from the Mike Evans Family Foundation to help United Means Suncoast and his hometown of Galveston, Texas, with relief efforts. Prop bets aren’t the only way to wager on the Super Bowl. Tampa Bay's protection is expected to step up this yr, but realistically a gaggle with a earlier 12 months's report of three-thirteen would not usually arrive again to play a brilliant bowl. By 1982, the Raiders moved to Los Angeles when Al Davis didn't make enhancements to the Oakland Coliseum till in 1995 he wrote a "letter of intent" indicating to maneuver the Raiders back to Oakland. So even for his detractors, and people who don't imagine in making the Tebowian movement, you got to offer the man some credit score: he turned around the Denver Broncos season and even managed to tie the Oakland Raiders for the primary place in the AFC West.

The deformation of the football when it is kicked or when the ball hits a floor is tested. If a defender interferes with a receiver throughout a move, where do officials spot the ball? Every time the offense strikes the ball a minimum of ten yards, they get a primary down. The signature poppies that are sometimes worn or sold as fundraisers for veterans originate in a poem referred to as "Flanders Fields." Poppies were the primary flowers to develop after battles passed off, and it's authorized to grow something apart from opium poppies in the U.S. In 2015, it was introduced that at $4-billion, the Cowboys are the world's most valuable franchise. Cam Newton had his best season with the Carolina Panthers in 2015 when he was named the leagues Most dear Player. Considered one of the newest Thanksgiving motion pictures is "The People," a highly relatable comedic drama launched in 2021. Finest described as a properly-acted, slow burn, the movie joins one family as they gather with their youngest daughter and her associate for Thanksgiving in her run-down New York City house. https://click4r.com/posts/g/17784880/7-tricks-to-develop-your-minnesota-vikings He may do all of it on the sphere and is now considered one of the newest members of the brand new York Jets football staff.

If you were watching a Detroit Lions game at Ford Area in Detroit and wanted a Latin-impressed dessert, you possibly can have ordered dessert nachos: tortilla chips lined in chocolate ganache and cinnamon sugar together with cherries and whipped cream. JPR Williams is without doubt one of the only a few gamers to have gained three grand slams. The Purple Sox won? It's school football season! He was first named mascot within the early 1900s. And right this moment, Invoice the Goat is still seen at Navy Faculty football games.S. Navy aircraft carriers. It first entered service in 1983 and serves with each the Navy and Marine Corps. Pacific fleet. Although this assault did cause appreciable harm, no carriers were destroyed as they weren't in dock at the time. It took the Astros a long time to win huge, however their performances turned out to be particularly extraordinary in mild of MLB's divisional realignment. Let's find out if you possibly can title these well-known sports films! Yes, he had dentures however they have been made out of supplies akin to gold, lead and ivory. Yes, the Naval Criminal Investigative Service does exist. This contest show is still going robust at present. Effectively, the U.S. Navy discovered during World Battle II about the facility of the aircraft provider and they nonetheless adhere to that as we speak.

Japan knew that warfare with the United States was inevitable. Navy and it stands for United States Ship. The Navy also can name on over 100,000 reserves and employs over 200,000 civilians. https://jsfiddle.net/silkturkey9/9qt8orpj/ In a T-bone collision, the car that has been hit from the aspect can nonetheless transfer forward in a roundabout way, that means that not the entire impact or momentum of the crash must be absorbed one hundred percent by the vehicles themselves. 2. By throwing the ball forward to a teammate, often called a forward pass or as passing the football. In Victoria, Australia, indigenous people performed a recreation called Marn Grook ("ball recreation"). Tyrell Williams is among the quickest receivers in the sport. Right this moment, SEALs are one of the crucial highly trained troopers on this planet. Navy. Would you understand who they're? Who played a outstanding function in its formation? Aging presents a series of function transitions: ending a profession for retirement, changing into a grandparent and even perhaps counting on assist from the identical kids who as soon as counted on you. Who is taken into account the father of the U.S.

The highest Gun faculty was formed in 1969 after it was determined that U.S. High school sports activities are way more thrilling. Since then, this NFC staff is on the longest championship title drought (sixty eight years) of any North American professional sports team. After six years and 5 completely different groups, Case Keenum became the beginning quarterback of which crew in 2018? Fortunately, most police forces have a special unit with the gear and coaching needed to resolve exactly this kind of situation: the SWAT group. That is more than most air forces in the world. The Pilgrims had sufficient food for the winter and had learned how to survive in the brand new World. Navy throughout World War II. Firstly, it was the first defeat it had ever tasted throughout World Battle II. The coin is the primary one issued by the U.S. John F. Kennedy did indeed serve with the U.S. True or false: President John F. Kennedy served in the U.S. Only the U.S. Air Power has extra aircraft (over 5,000). It even beats the Russian Air Pressure, which has simply over 3,000 aircraft.

Clearly rank is very important in any navy power. Some international locations have restricted the use of the time period “officer” to either certain ranks inside the police power or to members of the navy solely. The clubs have performed 258 matches towards one another, probably the most in German skilled football. This Professional Corkscrew Bottle Opener is a handy addition to any football get together. Wherever you locate the playroom, you will need lighting that is protected from the occasional football toss; straightforward-care flooring; and comfortable, movable, easy-to-clean furnishings. For some shots, the cameraman could need to shift the middle of gravity away from the gimbal, in order that the digital camera leans in a single route on its own. The historical Romans might have spent roughly the equal of $2 billion in right now's money to erect the Colosseum, according to calculations by historian and author Garrett Ryan. Bike pegs have been around for a pair hundred years but did not actually take off till the top of the millennium. All-in-all, the Continental Navy captured 55 British ships in two years. Join the Navy and see the world, they are saying. Navy. They have been based just after World Struggle II in 1946. Their display workforce presently consists of six McDonnell Douglas F/A-18 Hornets.

This study highlights the importance of using QoL tools in assessing the QoL of patients and the factors contributing to it.
Patients with better control over inter-dialysis weight gain (≤1600 g) had significantly higher scores. This study highlights the importance of using QoL tools in assessing the QoL of patients and the factors contributing to it.
Restricted outdoor activities and online learning during COVID-19 pandemic may pose threats on the physical and mental health of Chinese adolescents in middle schools. The study was to explore the relationship of Physical Activity (PA) and Sedentary Time (SED) with mood states among Chinese adolescents during the pandemic.

A total of 4898 adolescents (16.3 ± 1.3 years old) from 49 middle schools in 13 urban and rural areas in Yan'an, China volunteered to participate in this study and completed online questionnaires. International Physical Activity Questionnaire (IPAQ) were used to measure PA and SED, and Profile of Mood States were used to evaluate mood states. We used Mann-Whitney
-test and Kruskal-Wallis test to assess differences in PA and SED in different sex and grade group, respectively. Mixed linear regression was used to analyze the relationship between PA/SED and mood states.

Participants in our study accumulated 12.5 ± 26.0 min of moderate-to-vigorous PA and 363.6 ± 148.4 min of SED per day.chool had higher level of mood disturbance. More PA was associate with improving mood state among adolescents in the pandemic. https://www.selleckchem.com/products/ko143.html The present study may assist policymakers and healthcare professionals understand PA and mood states of Chinese adolescents during the epidemic and take targeted actions in case of emergencies in future.
Botulism is a severe neuroparalytic disease caused by toxins produced by several
species. This work presents the surveillance results of botulism in Iran, with the distribution of the cases by regions and by vehicle of transmission.

We describe the findings of the Centers for Disease Control and Prevention (CDC) surveillance on 2037 suspected cases of food-borne botulism during 2007-2017.

A total of 252 (12.3%) cases were confirmed to food-borne botulism. The mean annual incidence per 100,000 Iranian Natives was 7.1 cases for male individuals and 3.3 cases for female individuals. All botulism events were confirmed to be foodborne. The most commonly implicated food was home-prepared traditional processed fish product, followed by the consumption of commercially canned products and non-pasteurized dairy products. Forty-eight (19%) fatal botulism were reported which, the case-fatality rate declined from 4.5% to 0.7% during the study period.

Laboratory-based diagnosis of botulism is an imperative procedure to elucidate cases, particularly food-borne botulism, to identify toxins in food and confirm clinical diagnosis, helping sanitary control measures. In addition, educational materials related to botulism prevention should be disseminated to different communities.
Laboratory-based diagnosis of botulism is an imperative procedure to elucidate cases, particularly food-borne botulism, to identify toxins in food and confirm clinical diagnosis, helping sanitary control measures. In addition, educational materials related to botulism prevention should be disseminated to different communities.
HIV/AIDS program managers in Ho Chi Minh City (HCMC), Vietnam have always relied on the police reports and the UNAIDS Estimation and Projection Package for population size estimation of People Who Inject Drugs (PWID).

We used Respondent-driven Sampling (RDS) to implement a two-source capture-recapture study to estimate the population size of PWID in HCMC in 2017. The study was implemented in seven out of 24 districts and included men and women ages 18 years and older who reported injecting illicit drugs in the last 90 days, and who had lived in the city for the past six months. Estimates of the PWID population size for each of the seven districts were calculated accounting for the RDS sampling design. These were then adjusted to account for the district sampling probabilities to give an estimate for HCMC. Chapman two-source capture-recapture estimates of population size, based on simple random sampling assumptions, were also calculated for comparison.

The estimates resulted in a population size for HCMC of 19,155 [95% Confidence Interval (CI) 17,006-25,039] using the RDS approach and 17,947 (95% CI 15,968-19,928), using the Chapman approach.

The two-survey capture-recapture exercise provided estimates of PWID in HCMC - based on Chapman estimator and RDS approach - are similar. For planning HIV prevention and care service needs among PWID in HCMC, both estimates may need to be taken into consideration together with size estimates from other sources.
The two-survey capture-recapture exercise provided estimates of PWID in HCMC - based on Chapman estimator and RDS approach - are similar. For planning HIV prevention and care service needs among PWID in HCMC, both estimates may need to be taken into consideration together with size estimates from other sources.The demographics, clinical features, and histopathological classification of orbital space-occupying lesions in adults have not been widely described in our part of the world except for the pediatric population. In this retrospective study, we collected 110 consecutive adult patients (18 years and older) with orbital lesions (excluding lacrimal gland lesions) that were diagnosed histopathologically in two tertiary eye centers in Riyadh, Saudi Arabia (January 2000 to July 2017). Patients with thyroid-related orbitopathy, infectious, and inflammatory/pseudo-inflammatory lesions were excluded. We had 60 males (54.5%) and 50 females (45.5%). The mean age at presentation was 51.4 years (range 19-99). Proptosis was the most common clinical presentation (mean duration 15.4 months). The orbital lesions in order of increasing prevalence were lymphoproliferative lesions in 26.4%; vascular in 21.8%; secondary tumors in 14.6%; neurogenic in 13.6%; structural in 10.0%; soft tissue tumors 8.2%; then metastatic tumors (2.7%bital mass prior to surgical management planning and for future prognostic studies.
This study aimed to investigate the relationship between patients with severe sepsis or septic shock being transported to the Emergency Department (ED) by Emergency Medical Services (EMS) and the compliance with the 3-h sepsis resuscitation bundle [Surviving Sepsis Campaign (SSC)], and to compare the management and laboratory results of patients transported by EMS or non-EMS transport.

A retrospective cohort study was conducted using data from a quality-improvement project at King Abdulaziz Medical City in Riyadh. The data for patients who presented to ED with sepsis (severe sepsis or septic shock) was categorized as being transported with EMS or non-EMS. The two groups were compared in terms of compliance with the SSC bundle and 30-day mortality.

In a sample of 436 patients with severe sepsis or septic shock presented at the ED during the study period, EMS transported almost one-third of the patients (134, 31%) and 302 patients (69%) used non-EMS transport. For the EMS group, adherence to intravenous fluid was 91.4% compared with 87% for the non-EMS group (
= 0.19), antibiotics (EMS 50.7% vs non-EMS 52%,
= 0.81), blood cultures before antibiotics (EMS 53% vs non-EMS 47.4%,
= 0.21), and measuring lactate levels (EMS 73.1% vs non-EMS 57%,
= <0.01). The mortality rate was 48.5% for the EMS group and 54% for the non-EMS group, which was not statistically significant.

Whether transported with or without EMS did not result in a statistically significant difference in patients presenting with sepsis, in terms of the adherence to the SSC bundle elements or the 30-day hospital mortality rate. The only statistically significant difference was the time to lactate measurement.
Whether transported with or without EMS did not result in a statistically significant difference in patients presenting with sepsis, in terms of the adherence to the SSC bundle elements or the 30-day hospital mortality rate. The only statistically significant difference was the time to lactate measurement.
A systematic review.

To identify published studies that assess the prevalence and incidence of Low Back Pain (LBP) in the Saudi Arabian population.

Six electronic databases were searched for articles published between January 1995 and December 2018. Crosssectional or cohort studies were included if they were conducted in the KSA and focused on the prevalence or incidence of LBP in adults. Case-control and retrospective studies were excluded. Studies were also excluded if they did not meet the quality criteria set out by the Joanna Briggs Institute (JBI) assessment or had a high or medium risk of bias according to the criteria proposed by Hoy et al. One independent reviewer (MAA) verified that the studies met the inclusion criteria, and three independent reviewers (MAA, AHM, CMA) assessed the quality of the studies and extracted their relevant characteristics. All the studies were assessed for quality using the JBI assessment and were assessed for risk of bias according to the Hoy et al. approach.

The ctors such as; participants' specialities, years of experience and working load.

The prevalence of LBP is more common in female employee.

This review outlines the need for further epidemiology studies of the general population in the KSA.
This review outlines the need for further epidemiology studies of the general population in the KSA.
For last decades, the mortality rate of hajj pilgrims from Indonesia was between 2.1 and 3.2 per 1000 hajj pilgrims. At the same time, morbidity affected 87% of the elderly (>65 years old), of which 83% faced high risk of health problems. This is a complex problem affecting hajj health care in Indonesia. The study was aimed to understand what extent of the hajj implementation on health care in Indonesia.

This review was conducted by abstracting of three studies in Indonesian hajj health care. Two of the studies were based on cross-sectional reviews, while one was a case-control study. The majority of the studies performed laboratory tests to evaluate the disease conditions among hajj pilgrims through secondary data.

First study presented that hajj
(integrated post-coaching) was not functional in managing the health problems of the pilgrims. It shows that the stroke prevalence is 10.9 per 1000 people, Diabetes Mellitus (DM) 10.9% of the people, and coronary heart disease 1.5%. The second study exprcording to health isthitaah, which can be done by district health centers.To eliminate TB from the country by the year 2030, the Bangladesh National Tuberculosis (TB) Program is providing free treatment to the TB patients since 1993. However, the patients are still to make Out-of-their Pocket (OOP) payment, particularly before their enrollment Directly Observed Treatment Short-course (DOTS). This places a significant economic burden on poor-households. We, therefore, aimed to estimate the Catastrophic Health Expenditure (CHE) due to TB as well as understand associated difficulties faced by the families when a productive family member age (15-55) suffers from TB. The majority of the OOP expenditures occur before enrolling in. We conducted a cross-sectional study using multistage sampling in the areas of Bangladesh where Building Resources Across Communities (BRAC) provided TB treatment during June 2016. In total, 900 new TB patients, aged 15-55 years, were randomly selected from a list collected from BRAC program. CHE was defined as the OOP payments that exceeded 10% of total consumption expenditure of the family and 40% of total non-food expenditure/capacity-to-pay.

You can apply any time from instantly after coming into the nation till the expiry of your visa. An additional 3-month extension is possible (so in whole, 6 months), but you should once more pay the extension fee plus another Rs10,000. Extensions beyond this are on the discretion of the department, and incur a Rs15,000 fee plus the extension charge. Sri Lanka has greater than 2,500 years of steady written historical past by the use of the Mahawansha, and was additionally mentioned in a quantity of historic Indian texts.




Adding to the beautiful views are the ocean turtles nesting on the beaches, coral reefs adorning the seabed, whales breaching in the waters, and dolphins swimming in playful pods. The attractive highlands await you at present, so rise and shine for the scenic train journey to Nuwara Eliya. The evergreen hills and cool local weather made this city a major retreat for British colonialists within the nineteenth century, and a lot of buildings remain from this period.

Sri Lanka Journey Guide What To See, Know, And Do In Sri Lanka


Its excessive altitude and cooler local weather make the town among the many finest hiking locations in Sri Lanka. The hiking Ella Rock trail begins via a tea plantation and is simpler. You must know that some hikers and campers often face difficulty discovering the route.


Sale and public consumption of alcohol is forbidden on Poya Days, which usually fall on the date of the complete moon, but occasionally it falls a day either facet.
Reflecting its geographical position, native traditions mixed with a colonial imprint, in addition to locally grown tropical fruit and recent seafood, delicacies in Sri Lanka is a culinary delight.
Nestled within the verdant panorama are picturesque villages and towns, Ella being probably the most well-known.
From the blissfully tropical south to the untouched north, to the world’s greatest train journey and superior surf breaks, Sri Lanka is stuffed with superb things to see and do.


Minneriya National Park
From swimming to sunbathing, you presumably can interact in multiple leisure actions that excite you. The beach’s allure, infinite waves, and nearby road food outlets make this an ideal spot for rejuvenation. https://bestsritaxis.com and tourists visit this seaside for endless adventures, including seaside volleyball and swimming. So, witness the tranquil ambience and immerse yourself within the coastal beauty of Panadura.
For a culture-filled journey from Colombo, take the practice from Fort Railway Station to the heritage town of Kandy. It's a must for any rail enthusiast – the railway strains curve and wind around mountains to connect rural cities, and wide windows body views of deep ravines and hillsides densely covered in emerald-green forest. Don’t miss the opposite archaeological websites within the area, together with the closely grouped temples and stupas comprising the Royal Ruins, which can be explored on a rewarding day of sightseeing. No Sri Lanka itinerary would be complete without a journey to Colombo, the country’s culturally diverse capital city.
From watching gigantic statues and models to experiencing the essence of the photographs, you probably can glimpse into the rich history and affect of the -ism on folks worldwide. As artwork and literature fanatics, structure aficionados, and zealots, you possibly can have a nice time right here. Walk up the steps to the breathtaking hilltop and Kandy town views from the holy site- Bahiravakanda Vihara Buddha Statue.

Pack The Right Clothing For Sri Lanka’s Hills And Religious Sites
It is the birthplace of Buddhism, attracting lots of of pilgrims every year. The mountain is located near the town of Anuradhapura, where you can visit many non secular and historical constructions. Here, you can meditate, ascend the Aradhana Gala, and examine ancient ruins for the most effective time.
Mid-April is, nevertheless, New Year in Sri Lanka and the celebrations lead to packed trains and sold-out practice tickets. If you plan on seeing the east coast and the north a half of Sri Lanka, you’ll get the best climate from February to September. Ideally, you want to have more than two weeks on this itinerary, since it is pretty busy. We didn't spend an evening in Negombo but had a late flight out of Sri Lanka (after midnight), so we spent our final day in Sri Lanka hanging out on the Negombo Beach.
They don´t have lockers however just ask one of the staff on the station and they will put your bags in a storage room, and you may be given a receipt. Your finest and most convenient option is to pre-book your automotive & driver, who shall be ready for you in the arrival corridor holding up a board with your name on it. This is our really helpful two-week Sri Lanka itinerary crammed with all our favorite places to see and what we expect are the highest things to do in Sri Lanka.
Surrounded by the nearby jungle, these homes are constructed on a wooden platform up the tree. Book one of the treehouses at Back of Beyond in Sigiriya when you don’t mind visiting lizards and monkeys. During the season from April to August, this curl of soft, ocher sand comes alive at evening with events, booze and reside music. It also has a laid-back surf scene, together with the Arugam Bay Girls Surf Club, the first all-women membership in Sri Lanka, which holds swimming, browsing and yoga classes for the neighborhood. Originally forest-dwellers, their numbers have dwindled through the years due to migration, habitat loss, and assimilation into the nation's dominant Sinhala-Buddhist culture. Southern Sri Lanka produces some of the world's best cinnamon, a lighter, more sweeter selection than is present in Indonesia and Vietnam.