e bottom of the food chain, the diatoms are much more sensitive to changes in the environmental conditions than the fishes and they are more effective biological tools as toxic metal accumulation bioindicators.Pastoral areas are the key difficulty in China's pursuit of common prosperity and a key region for China to build the northern ecological safety barrier and to realize the Two Centenary Goals. It is of great significance to scientifically evaluate the quality of rural life (QRL), measure the relative poverty level (RPL), and identify the relatively poor areas, making it possible to dock poverty elimination with rural revitalization. Based on the socio-economic data of 18 pastoral areas in Inner Mongolia, this paper draws on spatial layout theory to evaluate QRL and measures RPL by the natural breakpoint method and then identifies the relatively poor areas in Inner Mongolia. The results show that (1) the QRLs of pastoral areas in Inner Mongolia were unbalanced and highly polarized. The mean score of QRLs was 0.2598. Eleven (61.11%) of the counties/banners had a QRL smaller than the mean score. On the spatial layout of QRLs, the western areas were stronger than the central areas. High QRL counties/banners are mnism against large-scale returning to poverty, aiming to lower composite RPL. The research results provide empirical reference and implementation path for consolidating the results of poverty eradication and facilitating rural revitalization.In anthropogenic soils, there have been relatively limited studies focusing on Cr and Ni contaminants because they exhibit less toxic effects to overall ecosystem and human health than other metal contaminants. In recent years, however, soil contamination with Cr and Ni has become a serious concern in several parts of the world because of the continuously increasing concentrations of these metals due to accelerated industrialization and urbanization. To investigate the status of soil contamination with Cr and Ni by anthropogenic activities, relevant global data sets in different land-use types reported by several studies were reviewed. This review presents the significant work done on Cr and Ni concentrations in roadside, central business district (CBD), and industrial soils in 46 global cities and evaluated their correlation by global data in the past few years. The highest concentrations of Cr and Ni were observed in industrial soils. Furthermore, a significant relationship was found between Cr and Ni concentrations in the soils, which might be because both metals are released from the same sources or anthropogenic activity processes. We also discuss the state of knowledge about the chemistry and distribution of Cr and Ni in the soil environment to understand how their processes such as redox reaction, precipitation-dissolution, and sorption-desorption affect the remediation of Cr- and Ni-contaminated soils using in situ immobilization technology. https://www.selleckchem.com/products/fg-4592.html Application of organic and inorganic immobilizing agents (e.g., lime, compost, and sulfur) for the clean-up of Cr- and Ni-contaminated soils has received increasing interest from several researchers worldwide. Several immobilizing agents have been suggested and experimentally tested with varying degrees of achievement in Cr- and Ni-contaminated soils. Overall, the use of sulfur-containing amendments and pH-increasing materials could be considered the best options for the remediation of co-contamination of Cr and Ni in soil.Anthropogenic and natural factors lead to substantial environmental degradation. This shift is aligned with the country's overall development, resulting in high demand for energy resources and a dramatic shift in human activities that contribute to haze pollution. Some of the countries in the South Asian region are ranked between one and twenty on the list of countries with the highest levels of PM2.5 pollution. The member countries have taken many steps to tackle global warming, but concern about haze pollution was found limited. Moreover, very little research was conducted on haze pollution, which led us to conduct this research in this region. This study used the panel data from 1998 to 2018 and a set of econometric models like long-term cointegrating relationship, fully modified ordinary least squares, and vector error-correction model Granger causality tests to examine the major drivers like anthropogenic and natural factors that might elevate haze pollution. Furthermore, our empirical results depict that (1) there is a long-term cointegrating relation between haze and the factors studied. (2) Energy consumption, urbanisation, and economic growth are the primary drivers of environmental degradation. (3) Rainfall has the most substantial influence on reducing haze pollution. The study concluded that (a) if the countries continue to develop at the same pace, all factors studied will continue to drive haze pollution to rise. (b) A decrease in PM2.5 pollution requires improvements in regional rainfall through vegetation, reducing reliance on fossil fuel-based energy sources, and increasing environmental education. (c) Slowing down the drive for urbanisation would not be cost-effective in reducing haze pollution in the region in the short run. Thus, reducing haze by adjusting the factors studied would not be easy in the short run and require the careful adoption of long-term policies.Over the last few decades, the globe is facing tremendous effects due to the unnecessary piling of municipal solid waste among which food waste holds a greater portion. This practice not only affects the environment in terms of generating greenhouse gas emissions but when left dumped in landfills will also trigger poverty and malnutrition. This review focuses on the global trend in food waste management strategies involved in the effective utilization of food waste to produce various value-added products in a microbiology aspect, thereby diminishing the negative impacts caused by the unnecessary side effects of non-renewable energy sources. The review also detailed the efficiency of microorganisms in the production of various bio-energies as well. Further, recent attempts to the exploitation of genetically modified microorganisms in producing value-added products were enlisted. This also attempted to address food waste valorization techniques, the combined applications of various processes for an enhanced yield of different compounds, and addressed various challenges. Further, the current challenges involved in various processes and the effective measures to tackle them in the future have been addressed. Thus, the present review has successfully addressed the circular bio-economy in food waste valorization.This study was carried out during two consecutive seasons, 2020 and 2021, on 12-year-old mango (Mangifera indica L.). cv. Ewaise grown in region Idku, El Beheira Governorate, Egypt. The trees were planted at 5 × 4 m apart and grafted on "Sokary" root stock to study the influence of zeolite and biochar on growth, yield, and fruit quality of "Ewaise" mango cultivar irrigated by agricultural drainage water. The trees were treated by the following treatments zeolite or biochar solely at 1, 2, and 3 kg for tree and their different combinations such as 1 kg zeolite + 1 kg biochar; 1 kg zeolite + 2 kg biochar; 1 kg zeolite + 3 kg biochar; 2 kg zeolite + 1 kg biochar; 2 kg zeolite + 2 kg biochar; 2 kg zeolite + 3 kg biochar; 3 kg zeolite + 1 kg biochar; 3 kg zeolite + 2 kg biochar; and 3 kg zeolite + 3 kg biochar as well as control zero soil application. The obtained results showed that the soil application of zeolite or biochar gave a positive effect on improving the soil characteristics which reflects on the tree trunk thickness, shoot length and thickness, number of inflorescences, yield in kg per tree, and fruit quality. The greatest positive effect on the previous mentioned parameters was obtained by the combined application of the soil application of 2 kg zeolite + 3 kg biochar; 2 kg zeolite + 2 kg biochar; 3 kg zeolite + 2 kg biochar; and 3 kg zeolite + 3 kg biochar over the rest-applied treatments or control in the two seasons.Education plays a significant role in the development of economies. This study empirically contributes to the literature by examining the impacts of higher education on CO2 emissions of BRICS economies over the period 1998-2020. For empirical analysis, we used the ARDL bound testing approach. The findings of the study show that higher education significantly and negatively contributed to the CO2 emissions of China and confirm the education-CO2-led hypothesis in the long run. The results of the study also reveal that higher education in Russia, India, and South Africa exerts a positive impact on CO2 emissions in the long run and rejects the education-CO2-led hypothesis. Moreover, financial inclusion has a negative impact on CO2 emissions in China, Russia, and South Africa, while financial inclusion positively affects CO2 emissions in only India in the long run. Based on findings, authorities should extend financial and social support for higher academic activities aimed at the mitigation of environmental pollution. Policymakers should also consider the synergy influence of financial inclusion in designing carbon mitigation policies.Following the EPA recommended method, a chronic diet risk assessment for pesticides was recently performed for adults and children in the Iranian population. The National Theoretical Maximum Daily Intake (NTMDI) for 32 pesticides was computed using the theoretical maximum residue limits (MRLs) of food consumption regulations and data from the comprehensive database of the Iranian Research Institute of Plant Protection (IRIPP). The risk was assessed by comparing TMDI with the acceptable daily intakes (ADI) evaluated by FAO. From 32 investigated pesticides, 10 pesticides had TMDI > 65% of the ADI. Some of these ADI-exceeding compounds (spirodiclofen, abamectin, trifloxystrobin, spiromesifen, fipronil, difenoconazole, tetraconazole) were found in citrus, cucumber, grapes, tomato, and potato as the foods that have played the most roles in the consumption of these pesticides. Furthermore, a probabilistic risk assessment was performed to estimate the contingency of extravagance of the ADI. In the current research, only cyazofamid in potato for children consumers exceeded the 1 of the HQ. However, carcinogenic risk (CR) due to spirodiclofen in citrus fruit and difenoconazole in tomato was higher than the 1E-6 value; therefore, consumers were at considerable carcinogenic risk in these commodities. This scrutiny is essential for improving the activities' risk assessment, regulation, and surveillance.This study aims to find the interaction between ionome and metabolome profiles of Pteris vittata L., an arsenic hyperaccumulator plant, to reveal its metal tolerance mechanism. Therefore, at the Pb-Zn mining sites located in Thai Nguyen province, Vietnam, where these species dominate, soil and plant samples were collected. Their multi-element compositions were analyzed using inductively coupled plasma mass spectrometry (ICP-MS) and thus referred to as the "ionomics" approach. In parallel, the widely targeted metabolomics profiles of these plant samples were performed using liquid chromatography-tandem mass spectrometry (UPLC-QqQ-MS). Nineteen elements, including both metals and nonmetals, were detected and quantified in both tissues of thirty-five plant individuals. A comparison of these elements' levels in two tissues showed that above-ground parts accumulated more As and inorganic P, whereas Zn, Pb, and Sb were raised mostly in the under-ground samples. The partial least squares regression (PLSR) model predicting the level of each element by the whole metabolome indicated that the enhancement of flavonoids content plays an essential contribution in adaptation with the higher levels of Pb, Ag, and Ni accumulated in the aerial part, and Mn, Pb in subterranean part.

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A financial storm is brewing! Discover the impact of bank failures & the rise of BRICs. Tune in to our FREE docu series!

https://www.brighteon.com/dd443697-3138-4168-a275-14f26cc82487

#FinancialSurvival #Gold #Silver #Dollarization #BRICs #Crypto #FinanceTips #Economy #Investing #MoneyMatters

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The aim of the article is to compare health system outcomes in the BRICS countries, assess the trends of their changes in 2000-2017, and verify whether they are in any way correlated with the economic context. The indicators considered were nominal and per capita current health expenditure, government health expenditure, gross domestic product (GDP) per capita, GDP growth, unemployment, inflation, and composition of GDP. The study covered five countries of the BRICS group over a period of 18 years. We decided to characterize countries covered with a dataset of selected indicators describing population health status, namely life expectancy at birth, level of immunization, infant mortality rate, maternal mortality ratio, and tuberculosis case detection rate. We constructed a unified synthetic measure depicting the performance of individual health systems in terms of their outcomes with a single numerical value. Descriptive statistical analysis of quantitative traits consisted of the arithmetic mean (xsr), stand system outcomes in BRICS countries. More research should be recommended to find them and determine to what extent and how exactly they affect health system outcomes. Copyright © 2020 Romaniuk, Poznańska, Brukało and Holecki.The burden of heart failure is disproportionately higher in African Americans, with a higher prevalence seen at an early age. Examination of racial differences in left ventricular mass (LVM) in childhood may offer insight into risk for cardiac target organ damage (cTOD) in adulthood. Central hemodynamic load, a harbinger of cTOD in adults, is higher in African Americans. The purpose of this study was to examine racial differences in central hemodynamic load and LVM in African American and non-Hispanic white (NHW) children. Two hundred sixty-nine children participated in this study (age, 10 ± 1 years; n = 149 female, n = 154 African American). Carotid pulse wave velocity (PWV), forward wave intensity (W1) and reflected wave intensity (negative area, NA) was assessed from simultaneously acquired distension and flow velocity waveforms using wave intensity analysis (WIA). Wave reflection magnitude was calculated as NA/W1. LVM was assessed using standard 2D echocardiography and indexed to height as LVM/[height (2.16) + 0.09]. A cutoff of 45 g/m (2.16) was used to define left ventricular hypertrophy (LVH). LVM was higher in African American vs. NHW children (39.2 ± 8.0 vs. 37.2 ± 6.7 g/m (2.16), adjusted for age, sex, carotid systolic pressure and socioeconomic status; p 0.05). NA/W1 was higher in African American vs. NHW children (8.5 ± 5.3 vs. 6.7 ± 2.9; p less then 0.05). Adjusting for NA/W1 attenuated racial differences in LVM (38.8 ± 8.0 vs. 37.6 ± 7.0 g/m (2.16); p = 0.19). In conclusion, racial differences in central hemodynamic load and cTOD are present in childhood. African American children have greater wave intensity from reflected waves and higher LVMI compared to NHW children. WIA offers novel insight into early life origins of racial differences in central hemodynamic load and cTOD. Copyright © 2020 Heffernan, Lefferts, Atallah-Yunes, Glasgow and Gump.Background Several non-invasive markers have been reported as being effective for the assessment of fibrosis in adults with chronic viral hepatitis. https://www.selleckchem.com/products/sn-38.html The infantile liver is more susceptible to cholestasis, and it is important to promptly evaluate liver fibrosis to guide the clinical treatment. However, the clinical value of these markers in infants with cholestasis remains unknown. Aim To investigate the correlation between serum laminin (LN), hyaluronic acid (HA), procollagen III N-terminal peptide (PIIINP) level, and liver fibrosis stage in infants with cholestasis. Methods One hundred and thirty-seven term infants with cholestasis were included. Laparoscopic exploration and cholangiography were performed to diagnose or rule out biliary atresia. Serum LN, HA, and PIIINP were measured prior to laparoscopic exploration. Liver biopsy was performed for all patients. Liver fibrosis was staged on a five-point scale (F0-F4) according to the METAVIR scoring system. The correlation between serum markers and liver fibor predicting liver fibrosis stage, especially cirrhosis. Its assessment is a simple and non-invasive diagnostic method for liver fibrosis in infants with cholestasis. Copyright © 2020 Wang, Pan, Zhao, Chen, Chen and Xia.Introduction Early rescue surfactant is the most effective way of administering surfactant but many infants still receive surfactant later. Our aim was to explore the association between timing of surfactant administration and the development of patent ductus arteriosus and other neonatal morbidities. Materials and method This retrospective study analyzed 819 preterm infants under 30 weeks of gestational age and under 1,500 g. Results Five hundred and ninety three infants received surfactant during the study period, of these 365 received it within 2 h of life (early group) and 228 received it after two h (late group). Patent ductus arteriosus was detected in 175 (48%) of the early group and 168 (74%) of the late group, p = 0.001. Multinominal logistic regression analysis demonstrated that receiving surfactant after 2 h of life has a OR 3.5 (2.2-5.64 95 % CI) and a p-value of 0.001 for developing patent ductus arteriosus. Conclusion In this study population we observed that late surfactant administration is associated with increased risk of patent ductus arteriosus. Copyright © 2020 Canpolat, Kadıoğlu Şimşek, Webbe, Büyüktiryaki, Karaçağlar, Elbayiyev and Kanmaz Kutman.Purpose To evaluate the diagnosis and treatment methods of hypospadias with megameatus intact prepuce (MIP). Materials and Methods A retrospective analysis was performed in 27 MIP children, 13 of whom underwent tubularized incised plate urethroplasty (TIP procedure), 7 underwent the Duplay procedure, 5 underwent the Mathieu procedure, 1 underwent meatal advancement and glanuloplasty (MAGPI procedure), and 1 underwent the glans approximation procedure (GAP). The patients were followed for 6-36 months to evaluate the surgical outcomes by the Pediatric Penile Perception Score (PPPS). Results A total of 27 patients with a mean age of 8.12 ± 3.0 years were enrolled in this study, and 25 cases (25/27, 92.6%) were accidentally discovered during the first visit for phimosis. The patients had a formed urethra of 0.5 to 1.5 cm. Complications occurred in 4 of the 27 patients (14.81%) 2 patients with urethral fistula and 2 patients with meatal stenosis. One patient had a case of self-healed urethral fistula, and the remaining 3 patients underwent reoperation.

05 relative to each other. G4 (32.77°C) and G5 (35.17°C) presented statistically significant differences between each other and among the other groups. All samples presented Ni, Ti, Cu and Al in different concentrations.

The chemical concentration of the elements that compose the alloy significantly influenced the thermodynamic and mechanical properties.
The chemical concentration of the elements that compose the alloy significantly influenced the thermodynamic and mechanical properties.
To assess the influence of elastomeric ligatures, subjected to a previous in vitro pigmentation process using different substances, on smile aesthetics during orthodontic treatment, from the perception of students and professionals.

Eight elastomeric ligatures of five commercial brands (3M/Unitek, American Orthodontics, Morelli, Ortho Technology, and Orthometric) (n=8) were immersed in coffee, Coca-Cola, and red wine for one minute per day, for 28 days; and another group of ligatures was immersed in artificial saliva. All samples were photographed and subsequently analyzed using the Adobe Photoshop software, by the RGB method. Afterwards, the pigmented ligatures were inserted in a patient wearing orthodontic brackets, and zoomed photographs of the smile were taken and presented to 40 evaluators, who filled in a satisfaction scale sheet to express their opinion on the smile aesthetics of each photograph. The color data were subjected to analysis of variance (ANOVA) and Tukey tests.

The substance with the highest pigmentation potential was coffee (p< 0.05) followed by red wine (p< 0.05). Comparison among the brands used in this study showed that American Orthodontics and Orthometric had the lowest degree of pigmentation when immersed in coffee and red wine (p< 0.05), respectively. However, the brand that showed the highest level of satisfaction among the evaluators was Ortho Technology.

The presence of pigmented elastomeric ligatures affected smile aesthetics, when compared with the control group.
The presence of pigmented elastomeric ligatures affected smile aesthetics, when compared with the control group.
A side effect observed in cases treated with extractions is the instability of orthodontic space closure.

The aim of this study was to investigate the influence of gingival invagination, presence of third molars and facial pattern, on the stability of orthodontic space-closure in the maxillary arch.

Ninety-nine subjects (41 male and 58 female) with Class I malocclusion treated with four premolars extraction were evaluated. Extraction sites reopening and gingival invaginations were evaluated in scanned dental models in the posttreatment and 1-year posttreatment stages (mean age 16.1 years). Third molars presence was evaluated at 1-year posttreatment panoramic radiographs, and the facial pattern (SN.GoGn) was evaluated in the initial lateral headfilms. Multiple logistic regression analysis was used to estimate the influence of the aforementioned independent variables on the frequency of extraction space reopening.

Space reopening was observed in 20.20% of the subjects 1-year post-debonding. Gingival invaginations were present in 25.73% of quadrants after debonding and in 22.80% 1-year posttreatment. The mean pre-treatment SN.GoGn was 35.64 degrees (SD=5.26). No significant influence was observed of the three independent variables on the instability of extraction site closure.

The presence of gingival invaginations, third molars and facial growth pattern do not seem to influence maxillary extraction sites reopening.
The presence of gingival invaginations, third molars and facial growth pattern do not seem to influence maxillary extraction sites reopening.
Schistosomiasis is a disease caused by Schistosoma. Due to its complex life cycle, evolutionary position and sexual dimorphism, schistosomes have several mechanisms of gene regulation. MicroRNAs (miRNAs) are short endogenous RNAs that regulate gene expression at the post-transcriptional level by targeting mRNA transcripts.

Here, we tested 12 miRNAs and identified their putative targets using a computational approach.

We performed the expression profiles of a set of miRNAs and their putative targets during the parasite's life cycle by quantitative reverse transcription-polymerase chain reaction (qRT-PCR).

Our results showed differential expression patterns of the mature miRNAs sma-miR-250; sma-miR-92a; sma-miR-new_4-3p; sma-miR-new_4-5p; sma-miR-new_5-5p; sma-miR-new_12-5p; sma-miR-new_13-3p and sma-miR-new_13-5p. https://www.selleckchem.com/products/ki20227.html Interestingly, many of the putative target genes are linked to oxidative phosphorylation and are up-regulated in adult-worms, which led us to suggest that miRNAs might play important roles in the post-transcriptional regulation of genes related to energetic metabolism inversion during parasite development. It is noteworthy that the expression of sma-miR-new_13-3p exhibited a negative correlation on SmNADHubiquinone oxidoreductase complex I.

Our analysis revealed putative miRNA genes related to important biological processes, such as transforming growth factor beta (TGF-β) signaling, proteasome regulation, glucose and lipid metabolism, immune system evasion and transcriptional regulation.
Our analysis revealed putative miRNA genes related to important biological processes, such as transforming growth factor beta (TGF-β) signaling, proteasome regulation, glucose and lipid metabolism, immune system evasion and transcriptional regulation.Our objective was to estimate the prevalence of excess weight and obesity, according to sex and income in the RPS Brazilian Birth Cohort Consortium (Ribeirão Preto, Pelotas, and São Luís). Participants in the Ribeirão Preto (1978/1979 and 1994), Pelotas (1982, 1993 and 2004) and São Luís (1997/1998) birth cohorts were included in different follow-ups from 7 years old onwards. Excess weight (overweight and obesity) were assessed by body mass index. The highest prevalences were observed in Ribeirão Preto (excess weight 27.7% at 9-11 and 47.1% at 22-23 years; obesity 8.6% at 9-11 and 19.8% at 22-23 years) while the smallest was in São Luís (excess weight 5.4 to 7-9 and 17.2% at 18-19 years; obesity 1.8% at 7-9 and 3.6% at 18-19 years). The younger the cohort, the greater the prevalence of excess weight and obesity when comparing similar age groups. Increases in obesity prevalence were greater than in excess weight prevalence. Women had lower excess weight prevalence in older cohorts and higher obesity prevalence in younger cohorts. Higher excess weight and obesity prevalence were observed in higher income children and adolescents, and in poorer adults. Differences in the prevalence of excess weight and obesity evidenced that individuals from younger cohorts are more exposed to this morbidity, as well as those who were born in the most developed city, low-income adults as well as children and adolescents belonging to families of the highest income tertile. Therefore, the results of this study indicate the need to prioritize actions aimed at younger individuals.The Brazilian legislation does not provide for a periodic review of the registration of pesticides and, even nowadays, products banned in other countries are still used. Based on the pesticide active substances registered in the country, the present study investigated the international regulatory situation in the following member countries Organization for Economic Co-operation and Development (OECD), European Community, and the BRICS (Brazil, Russia, India, China, and South Africa). Moreover, we sought to relate the main chronic effects to human health and the environment of the most commercialized pesticide active substances in Brazil in lists of classification of carcinogenic potential (US Environmental Protection Agency - USEPA and International Agency for Research on Cancer - IARC), endocrine disruption, and candidates for substitution, both from the European Community. A total of 399 pesticide active substances registered in Brazil for agricultural use were identified, excluding microbiological and biole reduction of the use of pesticides.Fertility reduction is a phenomenon observed in demographic transition. The demographic changes noted in female fertility represent a need for adjustment on health services regarding female health and family planning support. Thus, this study aimed to perform a descriptive analysis by tracing the sociodemographic profile of primiparous mothers belonging to nine Brazilian birth cohorts, in three cities from different states. Standardized questionnaires were applied to assess reproductive characteristics and covariables. Primiparous mothers were defined as women whose child included in birth cohorts was their firstborn child. Sample description was performed using analysis of variance (continuous variables) and chi-square (categorical variables). In total, 44,615 women were included in the analyses and 41.8% (95%CI 41.3; 42.2) were categorized as primiparous. The primiparity rates were the lowest in Ribeirão Preto (São Paulo State) 1978 (32%; 95%CI 30.9; 33.1) and the highest in most recent cohorts, reaching up to 50% of the participants (São Luís - Maranhão State 2010 47.2%; 95%CI 45.8; 48.6; Ribeirão Preto 2010 50.2%; 95%CI 49.1; 51.4); Pelotas (Rio Grande do Sul State) 2015 49.4% (95%CI 47.9; 50.9). Primiparous mothers' age and schooling increased over the years in all cohorts. Maternal age at the first childbirth behaved similarly in the three studied cities. There was an increase in the proportion of first-time mothers that were older, higher educated and belonged to richer income groups. Also, the proportion of teenage mothers (aged 15 years or younger) increased until the early 2000's and started decreasing around the years 2010, especially among women in the poorer income groups.This article discusses viral hepatitis, a theme addressed by the Clinical Protocol and Therapeutic Guidelines to Comprehensive Care for People with Sexually Transmitted Infections and, more precisely, by the Clinical Protocols and Therapeutic Guidelines for Hepatitis B and Hepatitis C and Coinfections, published by the Brazilian Ministry of Health. Besides the broad spectrum of health impairment, hepatitis A, B, and C viruses also present different transmission forms, whether parenteral, sexual, vertical, or fecal-oral. Among the strategies suggested for the control of viral hepatitis, in addition to behavioral measures, are expanded diagnosis, early vaccination against hepatitis A and hepatitis B viruses, and access to available therapeutic resources. Considering vertical transmission of the hepatitis B and hepatitis C viruses, screening for pregnant women with chronic hepatitis B and C is an essential perinatal health strategy, indicating with precision those who can benefit from the prophylactic interventions. Viral hepatitis A, B, and C are responsible for more than 1.34 million deaths worldwide every year, from which 66% are the result of hepatitis B, 30% of hepatitis C, and 4% of hepatitis A.This article addresses human papillomavirus (HPV) infection, one of the topics covered by the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health. The Protocol and Guidelines have been developed based on scientific evidence and validated in discussions with specialists. This article presents epidemiological and clinical aspects and guidelines for health service managers and health workers about diagnosing and treating people with papillomavirus infection. This theme is a significant public health issue since it is the most prevalent sexually transmitted infection globally, capable of triggering the oncogenic process of cervical cancer and the possibility of anogenital warts. Important information is presented for gaining knowledge about HPV and action strategies for infection prevention and control, provision of quality care, and effective treatment of the disease. Infection by the human papillomavirus is the sexually transmitted infection of the highest contagion, superior to genital herpes and HIV.